The relationship between polycystic ovary syndrome and coronary heart disease: a bibliometric analysis

Abstract

BackgroundPolycystic ovary syndrome (PCOS) is one of the most common gynecological endocrine diseases for women of puberty and reproductive age. PCOS can affect women’s health for the rest of their lives since the incidence of coronary heart disease (CHD) may increase in the perimenopausal and senile periods among PCOS women compared with non-PCOS women.MethodA literature retrieval based on the Science Citation Index Expanded (SCI-E) database. All obtained records results were downloaded in plain text format for subsequent analysis. VOSviewer v1.6.10, Citespace and Microsoft Excel 2010 software were utilized for analyzing the following terms: countries, institutions, authors, journals, references and keywords.ResultsThere were 312 articles retrieved from January 1, 2000 to February 8, 2023, and the frequency of citations was 23,587. The United States, England, and Italy contributed the majority of the records. Harvard University, the University of Athens, and Monash University were the top 3 most productive institutions with publications on the relationship between PCOS and CHD. Journal of clinical endocrinology & metabolism ranked first with the highest publications (24 records), followed by Fertility and sterility (18 records). The keywords were divided into six clusters in the overlay keywords network: (1) the correlation between CHD risk factors and PCOS women; (2) the relationship between cardiovascular disease and female reproductive system hormone secretion; (3) the interaction between CHD and metabolic syndrome; (4) the relationship between c-reactive protein and endothelial function and oxidative stress in PCOS patients; (5) the potential positive effect of metformin on reducing CHD risk factors in PCOS patients; (6) the study of serum cholesterol and body-fat distribution in patients with CHD in PCOS. Oxidative stress, genome-wide association, obesity, primary prevention, and sex difference were main hotspots in this field in recent five years according to the keyword citation burst analysis.ConclusionThe article obtained the hotspots and trends and provided a reference for subsequent research on the association between PCOS and CHD. Moreover, it is hypothesized that oxidative stress and genome-wide association were frontier hotspots in studies that explore the relationship between PCOS and CHD, and prevention research may be valued in the future.

Quality of Life of Women with Polycystic Ovary Syndrome

“…Some women with PCOS are turning to cosmetic procedures like laser hair removal. Given the potential risk of embolic complications with oral contraceptives, it is essential to approach patients individually, selecting the safest contraception type while considering contraindications and assessing risk factors for heart disease [42][43][44][45][46]. Therefore, comprehensive care is vital, tailoring treatment based on accompanying symptoms, conditions, and expected outcomes.…”

Knowledge mapping and global trends in the field of low-intensity pulsed ultrasound and endocrine and metabolic diseases: a bibliometric and visual analysis from 2012 to 2022

“…It offers a comprehensive and systematic assessment of the present research status, while also identifying potential avenues for future research within targeted fields. Bibliometrics effectively integrates information throughout the research process, enhances understanding, and assists in the deepening of knowledge regarding specific research areas ( 17 , 18 ). It has been noted that there is currently a lack of bibliometric analysis focusing on the recent cooperation and research trends of LIPUS, with a focus on endocrinology and metabolism.…”

Trends in metabolic dysfunction in polycystic ovary syndrome: a bibliometric analysis

“…Bibliometric analysis is based on mathematical and statistical methods to analyze all articles published on a research topic over a period of time, providing an overview of research categories or topics, co-authorship, keyword frequency and the most cited articles or journals, which is exactly what is needed to reveal the frontiers and hotspots of research into metabolic dysfunction in PCOS ( 12 , 13 ). Previous articles have been published on different aspects related to PCOS, which are coronary heart disease, insulin resistance and infertility ( 14 – 16 ). This is the first bibliometric analysis of PCOS metabolic dysfunction in the last ten years (2012–2021) to investigate the current status of research in this field.…”