The Relationship between Phospholipases A<sub>2</sub> and C in Signal Transduction

Lapetina, Eduardo G.; Crouch, Michael F.

doi:10.1111/j.1749-6632.1989.tb22606.x

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Cited by 8 publications

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Growth factor second messenger systems: Oncogenes and the heterotrimeric GTP‐;binding protein connection

Crouch

Hendry

1993

Medicinal Research Reviews

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We feel that there is now compelling evidence that the GTP-binding proteins play more than just a coordinating role in the actions of both tyrosine kinase and nontyrosine kinase receptor signal transduction. These similarities appear to represent just a small component of the convergence in the signaling pathways for structurally dissimilar receptor subsets. Future years will see further understanding of the intricacies of these G-protein-proto-oncogene interactions, and the extension into the potential role in growth factor action played by the expanding number of known members of this G-protein family.

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