The relationship between nutrition and depression in the life process: A mini-review

Ekinci, Gülseren Nur; Şanlıer, Nevin

doi:10.1016/j.exger.2022.112072

Cited by 38 publications

(27 citation statements)

References 80 publications

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“…Furthermore, there exists a notion that the influence of depressive symptoms on dietary exclusions might not be as pronounced as the impact of exclusions on the manifestation of depressive symptoms [ 101 ]. The influence of nutrients on mood disorders underscores the interconnectedness between individuals’ mental well-being and their nutritional status, the quality of their diet, and adequate intake of essential vitamins and minerals [ 102 ].…”

Section: Discussionmentioning

confidence: 99%

Exploring the Relationship between Mood Disorders and Coexisting Health Conditions: The Focus on Nutraceuticals

Mechlińska,

Wiglusz,

Słupski

et al. 2023

Brain Sciences

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Major depressive disorder and bipolar disorder are the leading causes of global disability. Approximately 50% of patients fail to attain remission, prompting a pronounced focus on the significance of dietary patterns and specific nutrients within the pathophysiology of mood disorders. The connection between chronic diseases and mood disorders follows a bidirectional pattern: physical ailments are interrelated with affective disorders, and, concurrently, mood symptoms often precede chronic diseases and have the potential to worsen their prognosis. Nutraceuticals affect factors that could potentially impact the onset of mood disorders: monoamines and brain-derived neurotrophic factor (BDNF) concentrations, neuroinflammation, oxidative stress, and sleep quality. Furthermore, mood disorders rarely manifest in isolation. Typically, such patients concurrently experience other mental disorders or somatic comorbidities: obesity, hypertension, diabetes, polycystic ovary syndrome (PCOS), etc., where providing nutritional support is also pertinent. To optimize the therapeutic approach for individuals with mood disorders, incorporating nutritional support may not solely ameliorate symptoms stemming directly from the mental condition, but also indirectly through interventions targeting comorbidities.

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Section: Discussionmentioning

confidence: 99%

Exploring the Relationship between Mood Disorders and Coexisting Health Conditions: The Focus on Nutraceuticals

Mechlińska,

Wiglusz,

Słupski

et al. 2023

Brain Sciences

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“…Kiwi, mango, avocado, peanut, almond, sunflower, wheat germ oil, shellfish, and goose meat are vitamin E-rich fruits. Depressive symptoms decrease with vitamin E[ 50 ]. Furthermore, Individuals with depression have been found to have reduced levels of minerals such as zinc, iron, phosphorus, calcium, magnesium, potassium, and sodium.…”

Section: Overview Of Tcmmentioning

confidence: 99%

Exploring the transformative impact of traditional Chinese medicine on depression: Insights from animal models

Yang,

Chen,

Xie

2024

World J Psychiatry

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Depression, a prevalent and complex mental health condition, presents a significant global health burden. Depression is one of the most frequent mental disorders; deaths from it account for 14.3% of people worldwide. In recent years, the integration of complementary and alternative medicine, including traditional Chinese medicine (TCM), has gained attention as a potential avenue for addressing depression. This comprehensive review critically assesses the efficacy of TCM interventions in alleviating depressive symptoms. An in-depth look at different research studies, clinical trials, and meta-analyses is used in this review to look into how TCM practices like herbal formulations, acupuncture, and mind-body practices work. The review looks at the quality of the evidence, the rigor of the methods, and any possible flaws in the current studies. This gives us an idea of where TCM stands right now in terms of treating depression. This comprehensive review aims to assess the efficacy of TCM interventions in alleviating depressive symptoms. In order to learn more about their possible healing effects, the study also looks into how different types of TCM work, such as herbal formulas, acupuncture, and mind-body practices.

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“…Folic acid is involved in the synthesis and metabolism of neurotransmitters associated with depression (serotonin, dopamine, norepinephrine). In addition, it plays a vital role in the regeneration of tetrahydrobiopterin (BH4), a cofactor essential for the formation of neurotransmitters [89].…”

Section: Vitamin B9 (Folic Acid)mentioning

confidence: 99%

Dietary Nutrient Deficiencies and Risk of Depression (Review Article 2018–2023)

2023

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Depression is classified as one of the most common mental disorders. Its prevalence has recently increased, becoming a growing public health threat. This review focuses on clarifying the role and importance of individual nutrients in the diet and the impact of nutrient deficiencies on the risk of depression. Deficiencies in nutrients such as protein, B vitamins, vitamin D, magnesium, zinc, selenium, iron, calcium, and omega-3 fatty acids have a significant impact on brain and nervous system function, which can affect the appearance of depressive symptoms. However, it is important to remember that diet in itself is not the only factor influencing the risk of or helping to treat depression. There are many other aspects, such as physical activity, sleep, stress management, and social support, that also play an important role in maintaining mental health. The data review observed that most of the available analyses are based on cross-sectional studies. Further studies, including prospective cohort, case-control studies, are recommended to draw more reliable conclusions.

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The relationship between nutrition and depression in the life process: A mini-review

Cited by 38 publications

References 80 publications

Exploring the Relationship between Mood Disorders and Coexisting Health Conditions: The Focus on Nutraceuticals

Exploring the Relationship between Mood Disorders and Coexisting Health Conditions: The Focus on Nutraceuticals

Exploring the transformative impact of traditional Chinese medicine on depression: Insights from animal models

Dietary Nutrient Deficiencies and Risk of Depression (Review Article 2018–2023)

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