The relationship between negative symptoms, social cognition, and social functioning in patients with first episode psychosis

García-López, María Ángeles; Alonso-Sánchez, Miguel; Leal, Itziar; Martín-Hernández, David; Caso, Javier R.; Díaz‐Caneja, Covadonga M.; Andreu-Bernabeu, Álvaro; Arango, Celso; Rodríguez‐Jiménez, Roberto; Sánchez-Pastor, Luis; Dı́az-Marsá, Marina; Mellor-Marsá, Blanca; Ibáñez, Ángela; Malpica, Norberto; Bravo-Ortiz, María-Fé; Baca‐García, Enrique; Ayuso-Mateos, José Luís; Izquierdo, Ana; Leza, Juan C.; Ayora, Miriam; Boi, Sara; Nuñez-Doyle, Aggie; Jiménez-Rodríguez, Olga; Albea, Julia García; Quijano, Jose Rodríguez; Sáiz-Ruiz, Jerónimo; León-Quismondo, Leticia; Muñoz-Sanjosé, Ainoa; Vidal-Villegas, Paz; García, Lucia Albarracin; Barrigon-Esteve, Maria Luisa; Torío, Iosune

doi:10.1016/j.jpsychires.2022.08.004

Cited by 11 publications

(4 citation statements)

References 81 publications

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“…26 Overall, these results further support the association between NS and cognitive impairment in individuals with SCZ. 27,28 A significant negative correlation has been reported between NS and prior cognitive functioning, and this correlation has been associated with poorer daily functioning [29][30][31][32] . However, there is limited research exploring how NS specifically impact cognitive functioning subfields.…”

Section: Discussionmentioning

confidence: 99%

Decline in Working Memory in Stable Schizophrenia May Be Related to Attentional Impairment: Mediating Effects of Negative Symptoms, a Cross-Sectional Study

Du,

Meng,

et al. 2024

NDT

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Background Schizophrenia (SCZ) is a severe mental illness, Cognitive deficits and negative symptoms (NS) are prevalent in individuals with SCZ and are crucial indicators of functional recovery. It is well known that cognitive symptoms and negative symptoms are interrelated and that negative symptoms can affect the ability to take cognitive tests. However, the specific relationship between attention, working memory (WM), and NS in stable SCZ remains unclear. This study aims to explore these associations and provide valuable insights for the subsequent treatment of SCZ. Methods We conducted a comprehensive assessment of 145 patients with stable SCZ using the Chinese Brief Neurocognitive Suite of Tests (C-BCT) and the Positive and Negative Symptom Scale (PANSS). Results Patients with abnormal cognition exhibited significantly higher PANSS total scores, cognitive symptom scores, and NS than those with normal cognition (P<0.05). Pearson’s correlation analysis revealed significant positive correlations between digital breadth(DB) and continuous operation(CO) (r=0.389, P<0.001), as well as a significant negative correlation between DB and NS (r=−0.291, P<0.001). Moreover, CO showed a negative correlation with NS (r=−0.173, P<0.05). However, no significant correlations were found between the digital breadth-anterograde score and CO or NS (r=0.148, P>0.05; r=−0.068, P>0.05). Notably, NS were identified as a mediator in the relationship between attention and WM (effect size=0.024). Conclusion Our findings highlight significant associations between WM, attention, and NS in individuals with stable SCZ. Moreover, attention not only directly impacts WM but also indirectly influences it through NS. Addressing cognitive deficits and NS in the treatment of SCZ may lead to improved overall outcomes for affected individuals.

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Section: Discussionmentioning

confidence: 99%

Decline in Working Memory in Stable Schizophrenia May Be Related to Attentional Impairment: Mediating Effects of Negative Symptoms, a Cross-Sectional Study

Du,

Meng,

et al. 2024

NDT

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“…A signi cant negative correlation has been reported between negative symptoms and prior cognitive functioning, and this correlation has been associated with poorer daily functioning [22][23][24] . However, there is limited research exploring how negative symptoms speci cally impact cognitive functioning sub elds.…”

Section: Discussionmentioning

confidence: 99%

Decline in working memory in stable schizophrenia may be related to attentional impairment: mediating effects of negative symptoms

Du,

Meng,

et al. 2023

Preprint

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Objective: Cognitive deficits and negative symptoms are prevalent in individuals with schizophrenia and are crucial indicators of functional recovery. However, the specific relationship between attention, working memory, and negative symptoms in stable schizophrenia remains unclear. This study aims to explore these associations and provide valuable insights for the subsequent treatment of schizophrenia. Methods: We conducted a comprehensive assessment of 145 patients with stable schizophrenia using the Chinese Brief Neurocognitive Suite of Tests (C-BCT) and the Positive and Negative Symptom Scale (PANSS). Results: Patients with abnormal cognition exhibited significantly higher PANSS total scores, cognitive symptom scores, and negative symptom scores than those with normal cognition（P<0.05）.Pearson's correlation analysis revealed significant positive correlations between digital breadth and sustained operation（r=0.389，P<0.001）,as well as a significant negative correlation between digital breadth and negative symptoms（r=-0.291，P<0.001）.Moreover, continuous manipulation showed a negative correlation with negative symptoms（r=-0.173，P<0.05）.However, no significant correlations were found between the digital breadth conformity score and persistent manipulation or negative symptoms（r=0.148，P>0.05；r=-0.068，P>0.05）. Notably, negative symptoms were identified as a mediator in the relationship between attention and working memory (effect size=0.024). Conclusion: Our findings highlight significant associations between working memory, attention, and negative symptoms in individuals with stable-phase schizophrenia. Moreover, attention not only directly impacts working memory but also indirectly influences it through negative symptoms. Addressing cognitive deficits and negative symptoms in the treatment of schizophrenia may lead to improved overall outcomes for affected individuals.

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“…In more severe cases, negative changes in cognition become a manifestation of negative changes to their identity. Negative changes in cognitive traits are also followed by continuously negative moods such as fear, anger, guilt, excessive shame and so on which give negative impacts such as suicidal ideation (Collett et al, 2016), decreased interest or participation in any activity, feeling alienated from others, or refusing to feel positive emotions when interacted with family or close friends (Besser et al, 2022;García-López et al, 2022).…”

Section: Posttraumatic Stress Disorder In Children: Conceptual Framew...mentioning

confidence: 99%

Reduce Students Post-Traumatic Stress Disorder Symptoms with Traditional Games: Play Therapy Based on Local Wisdom

Rusmana,

Hidayah,

Asrowi

et al. 2023

INT J INSTRUCTION

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The covid-19 epidemic, which has psychological effects on kids such anxiety and distress, served as the impetus for this study. The goal of the study was to determine whether typical game-based play therapy may help children with PTSD symptoms. In particular, the research would evaluate the instrument and reveal the effectiveness of the therapy in terms of the significance and nature of change. The study employed an experimental one-group pretest-posttest design, with elementary school sixth-graders meeting the inclusion criteria of having experienced traumatic events during the covid-19 pandemic. The diagnostic criteria instrument for PTSD symptoms was utilized. The processes for group therapy consisted of beginning a group, transition stage, performing stage, and termination stage. The analysis was conducted employing the RASCH model and the WINSTEP application. The results showed that the instrument had invalid items and was removed before analyzing the effectiveness of play therapy based on traditional games. Traditional game-based play therapy can alleviate PTSD symptoms in most students, although other students' PTSD symptoms remain unaffected. It is anticipated that future studies will explore the factors that influence the effectiveness of traditional game-based play therapy.

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The relationship between negative symptoms, social cognition, and social functioning in patients with first episode psychosis

Cited by 11 publications

References 81 publications

Decline in Working Memory in Stable Schizophrenia May Be Related to Attentional Impairment: Mediating Effects of Negative Symptoms, a Cross-Sectional Study

Decline in Working Memory in Stable Schizophrenia May Be Related to Attentional Impairment: Mediating Effects of Negative Symptoms, a Cross-Sectional Study

Decline in working memory in stable schizophrenia may be related to attentional impairment: mediating effects of negative symptoms

Reduce Students Post-Traumatic Stress Disorder Symptoms with Traditional Games: Play Therapy Based on Local Wisdom

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