The relationship between multiple sclerosis and neuropsychiatric syndromes

Fatigue and Affective Manifestations in Multiple Sclerosis—A Cluster Approach

“…In addition to fatigue, affective symptoms are particularly worrisome in this population. The last century has witnessed a growing literature on the existence of a potential link between MS and psychiatric manifestations [4]. Among these manifestations, anxiety and depression are of particular interest, could respectively affect 41%-50% of MS patients, and would be responsible for a deep suffering [5].…”