The Relationship Between Migraine and Atopic Disorders—the Contribution of Pulmonary Function Tests and Immunological Screening

Lee²,

et al. 2013

Journal of Asthma

Section: Discussionmentioning

confidence: 94%

“…Asthma patients with headache, especially daily headache, may have a lower quality of life than those without headache [10,11]. Although there have been sufficient studies showing an association between asthma and migraine, the relationship between asthma and daily headache has not been clarified [12][13][14][15].…”

Section: Introductionmentioning

confidence: 98%

Is daily headache related to asthma? Results from a population-based survey

Lee²,

et al. 2013

Journal of Asthma

“…[34][35][36] Migraine has been linked to a hypersensitive immune system. 37 However, Davey and associates 35 claim that the link appears to be independent of allergic mechanisms.…”

mentioning

confidence: 99%

Comorbidity in Migraine with Functional Somatic Syndromes, Psychiatric Disorders and Inflammatory Diseases: A Matter of Central Sensitization?

Grassini

Nordin

2015

Behavioral Medicine

To approach the questions as to why migraine appears to be associated with functional somatic syndromes (FSSs) and whether central sensitization may be an underlying mechanism, the present study investigated (a) comorbidity with diagnoses of three FSSs, three psychiatric disorders, and three inflammatory diseases, (b) degree of mental health problems (stress, burnout, anxiety, depression and somatization), and (c) prevalence of ten cognitive/affective and nine airway symptoms in persons with migraine in the general population. From a randomized and stratified Swedish adult sample, questionnaire data were analyzed from 151 individuals with a diagnosis of migraine and 3,255 without migraine. The results showed (a) significant comorbidity in migraine with all FSSs, psychiatric disorders and inflammatory diseases, (b) significantly elevated scores on stress, burnout, anxiety, depression, and somatization, and (c) relatively high prevalence rates on almost all symptoms. Taken together, the results motivate future study of central sensitization as a mechanism underlying migraine.

“…Another common feature of asthma and migraine is the presence of atopic characteristics that can be observed in patients. In a previous study, the prevalence of atopy in migraine patients was found to be near that in asthma patients [6].…”

Section: Introductionmentioning

confidence: 99%

Presence of Headache and Migraine in Asthma Patients

Turan¹,

Susuz²,

Turan³

2017

Turk Thorac J

OBJECTIVES:Migraine is a diseases characterized with severe headaches, with neurological and systemic findings. The purpose of this study is to investigate the prevalence of migraine and to examine whether there is a relationship between atopic disorders, parental history and migraine in asthma patients. MATERIAL AND METHODS:A total of 288 asthma outpatients, who had the diagnosis by an early or late test of reversibility showing a reversible airway obstruction according to hospital database were included. The presence of headache, atopic symptoms and parental history about asthma, atopic disorders and migraine were asked. The patients with headache were consultated by neurology department and investigated about the presence of migraine. The diagnosis of migraine headache was made if patients fulfilled the International Headache Society (IHS) criteria. RESULTS:60.4% of patients described a headache. There were 94 patients (32.6%) with headaches meeting the IHS criteria for migraine. Only 12 patients had migraine with aura. There were atopic symptoms in 86.8% of patients. According to parental history, there were asthma in 47.9%, atopic symptoms in 39.6% and migraine in 22.2% of parents. Patients with atopic symptoms were found to have significantly high rate of headaches (65.3%) "p=0.007". The prevalence of migraine was significantly high in patients with parental atopic symptoms (54%) "p=0.002". Multiple logistic regression analysis identified that gender, parental history of asthma, allergia and migraine, and smoking were independent risk factors for presence of migraine in asthmatics. CONCLUSION:There is a high prevalence of migraine headaches in patients with asthma. The coexistence of asthma and headaches may be related with a similar pathophysiological mechanism; parental history, common genetic compounds and smoking may play role in this mechanism. The headaches in asthma patients, atopic symptoms and family history should be questioned, and clinicians should be careful about the presence of migraine.