The Relationship between Malnutrition and Subjective Taste Change Experienced by Patients with Cancer Receiving Outpatient Chemotherapy Treatment

Özkan, İlknur; Taylan, Seçil; Eroğlu, Nermin; Kolaç, Nurcan

doi:10.1080/01635581.2021.1957485

Cited by 9 publications

(17 citation statements)

References 37 publications

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“…Previous findings on the association between TA and malnutrition are limited and controversial. One study found that half of patients with TAs were malnourished or at risk of malnutrition, and malnourished patients had more severe taste changes [ 16 ], and TAs have a serious effect on eating behaviors among cancer patients which might lead to nutritional deficiencies [ 7 , 10 ]. In contrast, a recent study found no statistically significant link between malnutrition and weight loss and taste and smell alterations [ 8 ], and dietary habits were not directly related to taste changes during chemotherapy [ 31 ].…”

Section: Discussionmentioning

confidence: 99%

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Taste alteration and its relationship with nutritional status among cancer patients receiving chemotherapy, cross-sectional study

Al-Amouri,

Badrasawi

2024

PLoS ONE

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The aim of this study is to determine the prevalence of taste alterations (TAs) during chemotherapy and their association with nutritional status and malnutrition. In addition to the associated factors with TA, including sociodemographic health-related factors and clinical status, and to investigate coping strategies to manage TA. A multicenter cross-sectional design study was conducted on 120 cancer patients aged at least 18 who had been undergoing at least one round of chemotherapy. TAs were evaluated using the chemotherapy-induced taste alteration scale (CiTAS), the malnutrition universal screening tool (MUST) was used for nutritional screening, the antineoplastic side effects scale (ASES) was used for subjective assessment of chemotherapy side effects, and the Charlson comorbidity index (CCI) was used for comorbidity assessment. SPSS21 software was used to analyze the data, and the independent T-test and one-way ANOVA test were used to determine the association between TAs and a variety of related variables. The prevalence of TAs was 98.3%. Among participants, 48.3% were at low risk of malnutrition, 20% at medium risk, and 31.7% at high risk. Malnutrition risk was associated with taste disorders (p<0.05). Patients’ age, gender, educational level, and physical status were associated with TAs (p<0.05). Type of cancer, chemotherapy regimen, and number of chemotherapy cycles were also associated with TAs (p<0.05). A variety of antineoplastic side effects were associated with TAs (p<0.05), including nausea, vomiting, dry mouth, sore mouth and throat, excessive thirst, swallowing difficulty, appetite changes, weight loss, dizziness, lack of energy, disturbed sleep, anxiety, and difficulty concentrating. TAs were associated with an increased number of comorbidities, and individuals with diabetes, pulmonary diseases, and hypertension were associated with TAs (P<0.05). Patients in this study rarely practice self-management strategies to cope with TAs. A high prevalence (98.3%) of TAs in cancer patients receiving chemotherapy was found, and it was linked to a variety of negative outcomes. Chemotherapy-induced TAs are an underestimated side effect that requires more attention from patients and health care providers.

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Section: Discussionmentioning

confidence: 99%

“…The sample size was estimated using the Coshrans’ formula for cross-sectional studies to determine the prevalence of taste changes. The prevalence of taste alteration was derived from a prior study conducted by Özkan et al [ 16 ]. It was 63%, with an anticipated difference of 10%, an alpha of 0.05, and a power of 80%.…”

Section: Methodsmentioning

confidence: 99%

Taste alteration and its relationship with nutritional status among cancer patients receiving chemotherapy, cross-sectional study

Al-Amouri,

Badrasawi

2024

PLoS ONE

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“…A cross‐sectional study indicated that hospitalized patients with cancer and GLIM‐defined malnutrition were more likely to present anxiety and depression assessed using the Hospital Anxiety and Depression Scale 34 . Another cross‐sectional study in patients with cancer receiving chemotherapy showed that patients with malnutrition or at risk of malnutrition evaluated using the Mini Nutritional Assessment tool had more severe subjective taste alteration, which was assessed utilizing the Chemotherapy‐induced Taste Alteration Scale 35 . The differences in the results may be due to the different study designs, participants' characteristics and assessment methods used to evaluate the symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…They received one fraction of intensity-modulated radiation every weekday. RT was delivered in 31.0 ± 2.2 [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] fractions with a total radiation dose of 65.3 ± 5.0 (36-75) Gy. The patients received 12.38 ± 2.14 fractions of RT at T 2 and 28.78 ± 2.68 fractions at T 3 .…”

Section: General Information Nutritional Risk and Nutritional Statusmentioning

confidence: 99%

“…34 Another cross-sectional study in patients with cancer receiving chemotherapy showed that patients with malnutrition or at risk of malnutrition evaluated using the Mini Nutritional Assessment tool had more severe subjective taste alteration, which was assessed utilizing the Chemotherapy-induced Taste Alteration Scale. 35 The differences in the results may be due to the different study designs, participants' characteristics and assessment methods used to evaluate the symptoms. The predictive effect of nutritional risk and malnutrition on these three NIS clusters in patients with HNC undergoing RT should be explored in future studies.…”

Section: T a B L Ementioning

confidence: 99%

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Predictive effect of pretreatment nutritional risk and GLIM‐defined malnutrition on the nutrition impact symptom clusters in patients with head and neck cancer undergoing radiotherapy

Wang

Zhang

et al. 2022

Head & Neck

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Background Evidence supporting predictive effects of pretreatment nutritional risk and nutritional status on nutrition impact symptom (NIS) clusters during radiotherapy in patients with head and neck cancer (HNC) is insufficient. Methods At baseline (T1), we collected severity and interference of NIS (Head and Neck Patient Symptom Checklist), nutritional risk, and nutritional status. During (T2) and at the end of radiotherapy (T3), we re‐evaluated NIS. Symptom clusters were identified by exploratory factor analysis using mean scores of NIS severity at T2 and T3. Predictive effects were explored by generalized estimating equations. Results Five hundred thirty‐seven patients were recruited and 334 of them completed. Four clusters were identified; the oropharyngeal symptom cluster was the most severe and had the greatest interference with diet. Patients with pretreatment nutritional risk or malnutrition experienced more severe oropharyngeal symptom cluster. Conclusions Pretreatment nutritional risk or malnutrition could predict the oropharyngeal symptom cluster in patients with HNC undergoing radiotherapy.

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Taste alterations in patients following hematopoietic stem cell transplantation: A qualitative study

Chen,

Fang,

Liu

et al. 2023

Asia-Pacific Journal of Oncology Nursing

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The Relationship between Malnutrition and Subjective Taste Change Experienced by Patients with Cancer Receiving Outpatient Chemotherapy Treatment

Cited by 9 publications

References 37 publications

Taste alteration and its relationship with nutritional status among cancer patients receiving chemotherapy, cross-sectional study

Taste alteration and its relationship with nutritional status among cancer patients receiving chemotherapy, cross-sectional study

Predictive effect of pretreatment nutritional risk and GLIM‐defined malnutrition on the nutrition impact symptom clusters in patients with head and neck cancer undergoing radiotherapy

Taste alterations in patients following hematopoietic stem cell transplantation: A qualitative study

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