“…On the other hand the 7-day regime may be too short to capture longer-term effects resulting from, for example neuroprotection, free-radical scavenging properties. Whilst the modulation of mood per se by extended treatment with ginseng has received little attention, the related constructs of 'quality of life' and 'well-being', which include a consideration of mood, have been investigated in a number of placebo-controlled trials, when administered alone (Sotaniemi et al, 1995;Wiklund et al, 1999;Cardinal and Engles, 2001;Ellis and Reddy, 2002) and in conjunction with vitamins and minerals (Wiklund et al, 1994;Neri et al, 1995;Ussher et al, 1995;Caso Marasco et al, 1996;Ussher and Swann, 2000). Effects have been evaluated using doses ranging from 80 to 400 mg in populations of various ages and stress levels (Wiklund et al, 1994;Neri et al, 1995;Sotaniemi et al, 1995;Ussher et al, 1995;Caso Marasco et al, 1996;Ussher and Swann, 2000;Cardinal and Engles, 2001;Ellis and Reddy, 2002), with study duration ranging between 2 and 9 months (see Coleman et al, 2003 for review).…”