The relationship between Gensini score and ST-segment resolution in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Zencirci, Aycan Esen; Zencirci, Ertuğrul; Değirmencioğlu, Aleks; Karakuş, Gültekin; Uğurlucan, Murat; Gündüz, Sabahattin; Özden, Kıvılcım; Erdem, Abdullah; Karadeniz, Fatma Özpamuk; Ekmekçi, Ahmet; Erer, Hatice Betül; Sayar, Nurten; Eren, Mehmet

doi:10.5603/kp.a2013.0355

Cited by 10 publications

(8 citation statements)

References 21 publications

(23 reference statements)

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“…Although different conclusions have been reached in earlier studies about the use of Gensini score in patients with Abbreviations as in Table 1 STEMI, recently, in their study, Zencirci et al [14] showed that the Gensini score plays an important role in inadequate resolution of ST segment in patients with STEMI undergoing primary percutaneous coronary intervention (PCI) [14]. On the other hand, SYNTAX score was defined initially for stable or unstable angina but then myocardial infarction SYNTAX score was defined for patients with STEMI treated with primary PCI in large-scale studies, and it was shown to be convenient and useful [15].…”

Section: Discussionmentioning

confidence: 87%

The relationship between fragmented QRS complexes and SYNTAX and Gensini scores in patients with acute coronary syndrome

et al. 2015

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Section: Discussionmentioning

confidence: 87%

The relationship between fragmented QRS complexes and SYNTAX and Gensini scores in patients with acute coronary syndrome

et al. 2015

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“…The left anterior descending (LAD) is the most commonly affected artery in both patient groups. Younger patients frequently present with single-vessel CAD 12,13 , fewer coronary lesions 12 and lower lesion complexity, as estimated by the Gensini score 11 which is a strong predictor of successful restoration of myocardial perfusion 14 as well as short and long-term adverse cardiovascular events 15 16 . Moreover, Gensini score was an independent predictor of long-term mortality in elderly individuals 17 .…”

Section: Coronary Plaque Featuresdifferences Between Elderly and Youn...mentioning

confidence: 99%

Risk factors profile of young and older patients with myocardial infarction

Sagris

Antonopoulos

Theofilis

et al. 2021

Cardiovascular Research

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Myocardial infarction (MI) among young adults (< 45 years) represents a considerable proportion of the total heart attack incidents. The underlying pathophysiologic characteristics, atherosclerotic plaque features and risk factors profile differ between young and older patients with MI. This review article discusses the main differences between the younger and elderly MI patients as well as the different pathogenic mechanisms underlying the development of MI in the younger. Young patients with MI often have eccentric atherosclerotic plaques with inflammatory features but fewer lesions, and are more likely to be smokers, obese, and have poor lifestyle, such as inactivity and alcohol intake. Compared to older MI patients, younger are more likely to be men, have familial-combined hyperlipidemia and increased levels of lipoprotein-a. In addition, MI in younger patients may be related to use of cannabis, cocaine use and androgenic anabolic steroids. Genomic differences especially in the pathways of coagulation and lipid metabolism have also been identified between young and older patients with MI. Better understanding of the risk factors and the anatomic and pathophysiologic processes in young adults can improve MI prevention and treatment strategies in this patient group. Awareness could help identify young subjects at increased risk and guide primary prevention strategies. Additional studies focusing on gene pathways related to lipid metabolism, inflammation and coagulation are needed.

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“…Hastalar GS'ye göre iki sınıfa bölündü: grup 1 (GS <32 olanlar, hafif KAH) ve grup 2 (GS ≥32 olanlar, ciddi KAH) (12). 11 (10)(11)(12)(13)(14) 11 (10)(11)(12)(13)(14) 0.846…”

Section: Koroner Anjiyografiunclassified

“…Çalışma gruplarının biyokimyasal ve ekokardiyografik özellikleri Tablo 2'de gösterilmektedir. Grup 2'deki hastalarda vWF (140 IU [101-149]'e karşın 120 IU [100-134], P=0.010), BK (10.5[8][9][10][11][12][13][14][15]'e karşın 9.7[7-12.3], P = 0.032), CRP (20 mg/dL'e karşın 11 mg/dL [4-37], P=0.038) ve ESH (20[14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29]'e karşın 14[10][11][12][13][14][15][16][17][18][19][20][21][22][23], P=0.007) anlamlı olarak daha yüksek idi. Yapılan korelasyon analizinde, gensini skoru ile vWF (r = 0.228, p = 0.007) ve ESH (r = 0.222, p = 0.010) arasında pozitif yönde korelasyon olduğu görüldü (Tablo 3).…”

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The Relationship between Plasma von Willebrand Factor Level and Severity of Coronary Artery Disease in Patients with Acute Coronary Syndrome

Taşçanov

Gungoren

2019

Harran Üniversitesi Tıp Fakültesi Dergisi

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Araştırma Makalesi/ Research Article Öz. Amaç: Koroner arter hastalığının yaygınlığını ve ciddiyetini değerlendirmek için anjiyografik bir skorlama sistemi olan Gensini skoru kullanılmaktadır. Yüksek Gensini skoru ve vonWillebrand faktör düzeyi akut koroner sendromlu hastalarda kötü kardiyak olaylar ile ilişkilidir. Bu çalışmada akut koroner sendromlu hastalarda Gensini skoru ile vonWillebrand faktör düzeyi arasındaki ilişkiyi araştırmayı planladık. Materyal ve Metot: Çalışmaya akut koroner sendrom tanısıyla koroner anjiyografi yapılan 141 hasta dahil edildi. Gensini skoru <32 olan hastalar grup 1, gensini skoru ≥ 32 olan hastalar ise grup 2 olarak tanımlandı. Her iki grup, anjiyografik özellikler ve plazma vonWillebrand faktör düzeyleri açısından karşılaştırıldı Bulgular: Grup 1 hastalar ile karşılaştırıldıklarında, grup 2 hastalarda vonWillebrand faktör düzeyi anlamlı olarak daha yüksek idi (140 IU [101-149]'e karşın 120 IU [100-134], P=0.010). Korelasyon analizinde gensini skoru ile vWF arasında pozitif bir korelasyon mevcuttu (r = 0.228, p = 0.007). Çok değişkenli lojistik regresyon analizinde, vWF yüksek Gensini skorunun bağımsız bir öngördürücüsü olarak tespit edildi (odds oranı, 1.013; % 95 güven aralığı, 1.002-1.026, P <0.027). vonWillebrand faktör sınır değerinin ≥ 128 IU alınması, % 59 duyarlılık ve % 63 özgüllük ile yüksek gensini skorunu öngördü. Sonuç: Akut koroner sendromlu hastalarda yüksek von Willebrand faktör seviyesi bağımsız olarak yüksek gensini skoru ile ilişkilidir.

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The relationship between Gensini score and ST-segment resolution in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Abstract: GS-pPCI and high thrombus burden play an important role in predicting inadequate STR in patients with STEMI treated with pPCI.

Cited by 10 publications

References 21 publications

The relationship between fragmented QRS complexes and SYNTAX and Gensini scores in patients with acute coronary syndrome

The relationship between fragmented QRS complexes and SYNTAX and Gensini scores in patients with acute coronary syndrome

Risk factors profile of young and older patients with myocardial infarction

The Relationship between Plasma von Willebrand Factor Level and Severity of Coronary Artery Disease in Patients with Acute Coronary Syndrome

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