The Relationship between Fluoride Concentration and the Caries Frequency of Different Tooth Surfaces in a High Fluoride Area

Candeli, A; Scavizzi, Ferdinando; Marci, F

doi:10.1159/000259628

Cited by 7 publications

(5 citation statements)

References 4 publications

(5 reference statements)

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“…This finding is consistent with the different fluoride content in each surface type (i.e. occlusal vs. smooth) [Candeli et al, 1970] and has been replicated in experimental studies of both fluoride mouthrinses [Ripa et al, 1985] and varnishes [Koch and Petersson, 1975]. However, evidence is lacking with regard to the caries-preventive efficacy of FV among different types of primary teeth, based either on tooth anatomy or existing pathology.…”

supporting

confidence: 79%

Surface-Specific Efficacy of Fluoride Varnish in Caries Prevention in the Primary Dentition: Results of a Community Randomized Clinical Trial

Divaris¹,

Preisser²,

Slade

2012

Caries Res

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Objectives: Fluoride varnish (FV) is efficacious in caries prevention although its effects among different tooth surfaces are poorly understood. This study sought to determine the extent to which caries-preventive effects of a community intervention that included FV application among preschool-aged children varied according to primary tooth anatomy and baseline tooth pathology. Methods: Secondary analysis was undertaken of data from a community-randomized controlled trial among 543 3- to 5-year-old Aboriginal children in 30 Northern Territory Australian communities. Children in intervention communities received community health promotion and FV application once every 6 months. Net caries (d₃mfs) risk and 95% confidence limits (CL) were estimated for the control and intervention arms, and stratified according to tooth anatomy/location and baseline pathology (sound, enamel opacity, hypoplastic defect or precavitated carious lesion). The intervention’s efficacy was quantified using generalized estimating equation modeling accounting for study design and clustering. The assumption of efficacy homogeneity was tested using a Wald χ² test with a p < 0.2 criterion and post hoc pairwise comparisons. Results: The intervention resulted in a 25% reduction (relative risk, RR = 0.75; 95% CL = 0.71, 0.80) in the 2-year surface-level caries risk. There was substantial heterogeneity in FV efficacy by baseline surface pathology: RRs were 0.73 for sound, 0.77 for opaque, 0.90 for precavitated, and 0.92 for hypoplastic surfaces. Among sound surfaces, maxillary anterior facials received significantly more benefit (RR = 0.62) compared to pits and fissures (RR = 0.78). Conclusion: The intervention had greatest efficacy on surfaces that were sound at baseline. Among those sound surfaces, maxillary anterior facials received most caries-preventive benefit.

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supporting

confidence: 79%

Surface-Specific Efficacy of Fluoride Varnish in Caries Prevention in the Primary Dentition: Results of a Community Randomized Clinical Trial

Divaris¹,

Preisser²,

Slade

2012

Caries Res

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“…N01-DE-12432. dalia et al, 1961;Candeli et al, 1970;De Paola et al, 1975;Bischoff et al, 1976;Keene et al, 1975;Englander and Mell berg, 1976;Poulsen and Larsen, 1975;Van der Merwe et al, 1977;Richards et al, 1977], Schamschula et al [1979] suggested that surface fluoride changes due to wear, pre vious caries challenge, or topical fluoride exposure might mask the true effect within a community, and in a small sample (n = 36) he found a significant correlation be tween caries and fluoride levels at enamel depths greater than 4 urn.…”

mentioning

confidence: 98%

The Relationship between Dental Caries and Tooth Enamel Fluoride

Mellberg

Ripa²,

Leske

et al. 1985

Caries Res

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Four thin layers of enamel totaling approximately 8 μm were removed from each of two bicuspids in 215 subjects, age 14–24 years, and analyzed for fluoride. The concentration of fluoride in the outer layers decreased significantly with subjects’ age. A small but statistically significant correlation between enamel fluoride and DMFS of individual subjects was found. Correlations were somewhat stronger in the outer enamel layers and in subjects from nonfluoridated areas.

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“…In several of these studies no significant correlation could be established between dental caries experience and enamel F concentration [Candeli et al, 1970;Keene et al, 1975;Poulsen and Larsen, 1975;Bischoff et al, 1976;Richards et al, 1977;Van der Merwe et al, 1977;Retief et al, 1979a;Nasir et al, 1985]. In another study no significant association between the F concentration in surface enamel and den tal caries was obtained but significant in verse correlations between DM FT and the F concentrations in the subsurface enamel layers were recorded [Schamschula et al, 1979).…”

mentioning

confidence: 98%

Relationship between Enamel Fluoride Concentration and Dental Caries Experience

1987

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Enamel biopsies for F analysis were performed on the mesial, buccal, distal and lingual surfaces of contralateral pairs of premolars extracted from 104 10- to 14-year-old children. Five successive etchings, each of 5 s duration, were carried out on the mesial and buccal surfaces with 2 M HClO₄, and 5 successive etchings, each of 2 s duration, were performed on the distal and lingual surfaces using 0.5 M HClO₄. The F concentrations were adjusted to standardized depths and the F concentrations at individual and cumulative etch depths determined. The caries experience of the children was expressed as filled teeth (FT) or filled surfaces (FS). Highly significant correlations (p = 0.0001) between age and FT and FS were obtained. No significant relationship between dental caries experience and enamel F concentration was established in the present study except for a significant correlation between dental caries and the enamel F concentration in the outermost 10 μm on the buccal aspects of the premolar teeth.

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The Relationship between Fluoride Concentration and the Caries Frequency of Different Tooth Surfaces in a High Fluoride Area

Cited by 7 publications

References 4 publications

Surface-Specific Efficacy of Fluoride Varnish in Caries Prevention in the Primary Dentition: Results of a Community Randomized Clinical Trial

Surface-Specific Efficacy of Fluoride Varnish in Caries Prevention in the Primary Dentition: Results of a Community Randomized Clinical Trial

The Relationship between Dental Caries and Tooth Enamel Fluoride

Relationship between Enamel Fluoride Concentration and Dental Caries Experience

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