The relationship between cognition and functioning in schizophrenia: A semi-systematic review

Kharawala, Saifuddin; Hastedt, Claudia; Podhorná, Jana; Shukla, Hemlata; Kappelhoff, Bregt S; Harvey, Philip D.

doi:10.1016/j.scog.2021.100217

Cited by 41 publications

(39 citation statements)

References 62 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As said before, MMN is an index of basic cognitive processes, which are usually impaired in subjects with schizophrenia [46][47][48][49]. Our results concerning the association between MMN and functioning might be interpreted in the light of the influence of deficits in cognitive processes on functioning in subjects with schizophrenia, a finding which has been extensively reported in literature [49,145,146]. This relationship is complex and mostly indirect, with many variables, such as social cognition, negative symptoms, and functional capacity, acting as mediators and moderators in the pathway from cognitive impairment to functioning [66][67][68][69]145,147].…”

Section: Discussionsupporting

confidence: 81%

“…Our results concerning the association between MMN and functioning might be interpreted in the light of the influence of deficits in cognitive processes on functioning in subjects with schizophrenia, a finding which has been extensively reported in literature [49,145,146]. This relationship is complex and mostly indirect, with many variables, such as social cognition, negative symptoms, and functional capacity, acting as mediators and moderators in the pathway from cognitive impairment to functioning [66][67][68][69]145,147]. Moreover, cognitive deficits are associated with everyday life skills, independent living, and occupational functioning [145].…”

Section: Discussionsupporting

confidence: 72%

“…This relationship is complex and mostly indirect, with many variables, such as social cognition, negative symptoms, and functional capacity, acting as mediators and moderators in the pathway from cognitive impairment to functioning [66][67][68][69]145,147]. Moreover, cognitive deficits are associated with everyday life skills, independent living, and occupational functioning [145]. This is in line with our results, which provide a deeper knowledge about the impact of basic cognitive processes alterations, as indexed by MMN amplitude reduction, on functioning in subjects with schizophrenia.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Mismatch Negativity and P3a Impairment through Different Phases of Schizophrenia and Their Association with Real-Life Functioning

Giordano

Giuliani

Perrottelli

et al. 2021

JCM

View full text Add to dashboard Cite

Impairment in functioning since the onset of psychosis and further deterioration over time is a key aspect of subjects with schizophrenia (SCZ). Mismatch negativity (MMN) and P3a, indices of early attention processing that are often impaired in schizophrenia, might represent optimal electrophysiological candidate biomarkers of illness progression and poor outcome. However, contrasting findings are reported about the relationships between MMN-P3a and functioning. The study aimed to investigate in SCZ the influence of illness duration on MMN-P3a and the relationship of MMN-P3a with functioning. Pitch (p) and duration (d) MMN-P3a were investigated in 117 SCZ and 61 healthy controls (HCs). SCZ were divided into four illness duration groups: ≤ 5, 6 to 13, 14 to 18, and 19 to 32 years. p-MMN and d-MMN amplitude was reduced in SCZ compared to HCs, independently from illness duration, psychopathology, and neurocognitive deficits. p-MMN reduction was associated with lower “Work skills”. The p-P3a amplitude was reduced in the SCZ group with longest illness duration compared to HCs. No relationship between P3a and functioning was found. Our results suggested that MMN amplitude reduction might represent a biomarker of poor functioning in SCZ.

show abstract

Section: Discussionsupporting

confidence: 81%

Section: Discussionsupporting

confidence: 72%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Mismatch Negativity and P3a Impairment through Different Phases of Schizophrenia and Their Association with Real-Life Functioning

Giordano

Giuliani

Perrottelli

et al. 2021

JCM

View full text Add to dashboard Cite

show abstract

“…Neuropsychologische Defizite sind bei Menschen mit erhöhtem Risiko für eine Psychose oft bereits vorhanden und zählen zu jenen Faktoren, welche die Vulnerabilität für die Manifestation einer Psychose erhöhen [5] und das Zurechtkommen in der realen Welt prädizieren [6]. Soziale Kognition wurde als grundlegender Mediator identifiziert, welcher den Zusammenhang zwischen Neurokognition und funktionalem Outcome vermittelt [5].…”

Section: » Psychotische Erfahrungen Gehen Mit Einschränkungen Der Soz...unclassified

“…Soziale Kognition wurde als grundlegender Mediator identifiziert, welcher den Zusammenhang zwischen Neurokognition und funktionalem Outcome vermittelt [5]. Vor allem die Negativsymptomatik (Affektverflachung, Alogie, Avolition, Asozialität, Anhedonie) zeigte sich für den Zusammenhang zwischen Kognition und Outcome verantwortlich [6].…”

Section: » Psychotische Erfahrungen Gehen Mit Einschränkungen Der Soz...unclassified

Affektregulation und soziale Kognition bei Psychose

Steinmair

Masic

Schwigon

et al. 2022

psychopraxis. neuropraxis

View full text Add to dashboard Cite

ZusammenfassungGelingende soziale Interaktionen sind für das Wohlbefinden eine entscheidende Komponente; Sozialität ist ein Merkmal menschlicher Gruppen. Psychose und Begegnung im sozialen Umfeld stellen eine Herausforderung an die Beziehungsgestaltung dar. Subtile Interventionen von TherapeutInnenseite können eine erfolgreiche Interaktion bewirken. Entscheidend ist die Berücksichtigung der Affektregulation.

show abstract

Validation of a modified Chinese‐language version of the Davos Assessment of Cognitive Biases Scale (MCL‐DACOBS) in a sample of Chinese patients with schizophrenia

Chen

Tian

et al. 2023

Brain and Behavior

View full text Add to dashboard Cite

IntroductionThe Davos Assessment of Cognitive Biases Scale (DACOBS) is widely used to assess cognitive biases in patients who have schizophrenia. However, the lack of a modified Chinese‐language version of the DACOBS (MCL‐DACOBS) precludes Chinese schizophrenic patients from treatment aimed at normalizing cognitive biases, impacting their prognosis. Here, we aimed to produce a DACOBS for China and test the validity and reliability of the resultant MCL‐DACOBS.MethodsEighteen researchers collaborated to develop the MCL‐DACOBS: A total of 15 researchers modified and translated the English version of the DACOBS, 1 native‐English‐speaking researcher back‐translated the scale, and 2 Chinese sinologists localized and optimized the language of the MCL‐DACOBS. Forty‐two volunteers checked the scale items’ comprehensibility, and the two sinologists performed further localization and optimization based on their feedback. The final version of the MCL‐DACOBS used in this study was thus derived from the harmonized English‐language version of the scale. Confirmatory factor analyses (CFAs) were used to examine the best latent structure of the MCL‐DACOBS. Cronbach's α and intraclass correlation coefficients (ICCs) were used to check the reliability. The discriminative ability of the MCL‐DACOBS was assessed according to the area under the receiver operating characteristic curve.ResultsThe CFA showed that all items loaded onto factors with loadings >0.400. A two‐factor structure showed a good model fit (root mean square error of approximation = .018, Tucker–Lewis index = .978, comparative fit index = .984). Promax rotation demonstrated that each item had a high factor load (0.432–0.774). Cronbach's α coefficient and ICC for the MCL‐DOCABS were .965 and .957, respectively, indicating that the scale has ideal reliability.ConclusionThe MCL‐DACOBS has good validity and good reliability, and its psychometric properties indicate that it is a valid tool for measuring cognitive biases in Chinese patients with schizophrenia.

show abstract

The relationship between cognition and functioning in schizophrenia: A semi-systematic review

Cited by 41 publications

References 62 publications

Mismatch Negativity and P3a Impairment through Different Phases of Schizophrenia and Their Association with Real-Life Functioning

Mismatch Negativity and P3a Impairment through Different Phases of Schizophrenia and Their Association with Real-Life Functioning

Affektregulation und soziale Kognition bei Psychose

Validation of a modified Chinese‐language version of the Davos Assessment of Cognitive Biases Scale (MCL‐DACOBS) in a sample of Chinese patients with schizophrenia

Contact Info

Product

Resources

About