The relationship between clinical symptoms and pollen count in pollinosis

Sack, S.Senior; Golan, Harry G.

doi:10.1016/s0021-8707(42)90168-0

Cited by 7 publications

(4 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A high proportion of the patients, irrespective of their clinical sensitivity, continued to have symptoms late in the pollen season, v^-hen the pollen counts were low. High symptoms in relation to pollen counts late in the ragweed season have been reported previously (Lichenstein et ai, 1966;Sack & Golan, 1942). A probable explanation for this phenomenon would be a decreased nasal threshold after the environmental exposure to pollen, 'the priming of the end organ" suggested by Connell (1968).…”

Section: Discussionmentioning

confidence: 63%

“…The importance of a quantitative pollen count in obtaining the clinical history of the patients and in the evaluation of the treatment of respiratory allergic diseases has been emphasized (Norman, 1969;Davies, 1975). A good correlation between the symptoms of the patients and the pollen counts has been found in a number of studies (Sack & Golan, 1942;Lowell &Frankhn. 1963;Brown & Ipsen, 1968;Norman, Winkenwerder & Lichtenstein, 1968).…”

Section: Introductionmentioning

confidence: 61%

See 1 more Smart Citation

The seasonal symptoms of hyposensitized and untreated hay fever patients in relation to birch pollen counts: correlations with nasal sensitivity, prick tests and RAST

Viander

Koivikko

1978

Clin Experimental Allergy

109

View full text Add to dashboard Cite

A 2 year prospective study of thirty-eight birch pollen-sensitive hay fever patients under specilic immunotherapy and of nineteen untreated control patients showed a significant correlation between the total seasonal symptom scores of the patients and their clinical sensitivities assessed by the RAST and a graded nasal test. The agreement between a positive nasal test and a positive RAST was 74%. In the early season with low pollen counts the onset of symptoms was significantly associated with high sensitivity of the patients, while many patients showed symptoms in the late season irrespective of their nasal and RAST sensitivity. About 90% of both the treated and the untreated patients reported mild symptoms when the pollen count exceeded 80/m^ in the early season. 80% of them still had symptoms when the count was below 30/m^ in the late pollen season. Although hyposensitization therapy had no effect on the occurrence of the mild symptoms, the treated patients had severe symptoms significantly less often than the untreated ones on days with high pollen counts.

show abstract

Section: Discussionmentioning

confidence: 63%

Section: Introductionmentioning

confidence: 61%

The seasonal symptoms of hyposensitized and untreated hay fever patients in relation to birch pollen counts: correlations with nasal sensitivity, prick tests and RAST

Viander

Koivikko

1978

Clin Experimental Allergy

109

View full text Add to dashboard Cite

show abstract

“…The HRQL is an important aspect that should be taken into account in the clinical follow up and is recommended to be included in clinical studies [7]. Atmospheric pollen counts are considered to be positively correlated with allergic symptomatology [8]. This has then been confirmed in numerous studies [9–12] but the delay of symptoms after the exposure, the impact of earlier exposure (priming and lag effects) and possible changes in reaction patterns during the course of the season have been less often described, just as differences in reaction patterns between different organs.…”

Section: Introductionmentioning

confidence: 99%

Grass pollen allergy in children and adolescents‐symptoms, health related quality of life and the value of pollen prognosis

Kiotseridis

Cilio

Bjermer

et al. 2013

Clinical & Translational All

View full text Add to dashboard Cite

IntroductionAn association between pollen count (Poaceae) and symptoms is well known, but to a lesser degree the importance of priming and lag effects. Also, threshold levels for changes in symptom severity need to be validated. The present study aims to investigate the relationship between pollen counts, symptoms and health related quality of life (HRQL), and to validate thresholds levels, useful in public pollen warnings.Material and methodsChildren aged 7–18 with grass pollen allergy filled out a symptom diary during the pollen season for nose, eyes and lung symptoms, as well as a HRQL questionnaire every week. Pollen counts were monitored using a volumetric spore trap.Results89 (91%) of the included 98 children completed the study. There was a clear association between pollen count, symptom severity and HRQL during the whole pollen season, but no difference in this respect between early and late pollen season. There was a lag effect of 1–3 days after pollen exposure except for lung symptoms. We found only two threshold levels, at 30 and 80 pollen grains/m3 for the total symptom score, not three as is used today. The nose and eyes reacted to low doses, but for the lung symptoms, symptom strength did hardly change until 50 pollen grains/m3.ConclusionGrass pollen has an effect on symptoms and HRQL, lasting up to 5 days after exposure. Symptoms from the lungs appear to have higher threshold levels than the eyes and the nose. Overall symptom severity does not appear to change during the course of season. Threshold levels need to be revised. We suggest a traffic light model for public pollen warnings directed to children, where green signifies “no problem”, yellow signifies “can be problems, especially if you are highly sensitive” and red signifies “alert – take action”.

show abstract

“…Se ha derscrito que algunos pacientes pueden presentar síntomas después de unos días de lluvia, como consecuencia de una reacción tardia (Frenz DA. 2001) (Sack S, 1942) La exposición humana a los pólenes también es variable, puede aumentar dependiendo de la actividad, como cortar el césped, ir en el automóvil con las ventanillas bajadas o realizar ejercicio al aire libre (Muilenberg ML, 1991), y del lugar donde se reside (Solomon WR 1984).…”

Section: Factores Que Pueden Interferir En La Correlación Recuentos-sunclassified

Aplicación y utilidad del diagnóstico basado en componentes moleculares en pacientes alérgicos al polen de cupresaceas

Anibarro¹,

Jaime²

View full text Add to dashboard Cite

CUALES SON………………………………………………….………165 6.7.1Identificación delas sensibilizaciones según los resultados de SPT………………………….…………………………………….165 6.7.2 Monosensibilización y cosensibilización según nCup a 1/ Phl p1-5…………………………..…………….……………………..165 6.7.3 Caracterización de los pacientes. ………………...………166 6.8 EVALUACIÓN LA SENSIBILIZACIÓN A ALÉRGENOS DE REACTIVIDAD CRUZADA. ………………..…….………………..166 6.8.1 Comparativa en las pruebas diagnósticas según los dos fenotipos. ………………………………….…….

show abstract

The relationship between clinical symptoms and pollen count in pollinosis

Cited by 7 publications

References 3 publications

The seasonal symptoms of hyposensitized and untreated hay fever patients in relation to birch pollen counts: correlations with nasal sensitivity, prick tests and RAST

The seasonal symptoms of hyposensitized and untreated hay fever patients in relation to birch pollen counts: correlations with nasal sensitivity, prick tests and RAST

Grass pollen allergy in children and adolescents‐symptoms, health related quality of life and the value of pollen prognosis

Aplicación y utilidad del diagnóstico basado en componentes moleculares en pacientes alérgicos al polen de cupresaceas

Contact Info

Product

Resources

About