The relationship between chronic exposure to arsenic through drinking water and hearing function in exposed population aged 10–49 years: A cross-sectional study

Shokoohi, Reza; Khazaei, Mohammad; Karami, Manoochehr; Seid‐Mohammadi, Abdolmotaleb; Berijani, Nima; Khotanlou, Hassan; Torkshavand, Zahra

doi:10.1016/j.ecoenv.2021.111939

Cited by 13 publications

(6 citation statements)

References 32 publications

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“…Neuropathy and peripheral neuropathy are common complications seen with arsenic toxicity. Neuropathy is a condition in which sensory function is impacted upon chronic exposure to toxicants or metabolic disorders [ 120 ]. A study in Mexico observed that urinary arsenic concentration was conversely correlated with oral IQ (verbal intellectual ability) and memory.…”

Section: Neuronal Effects Of Arsenicmentioning

confidence: 99%

Molecular Mechanism of Arsenic-Induced Neurotoxicity including Neuronal Dysfunctions

Thakur

Rachamalla

Niyogi

et al. 2021

IJMS

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Arsenic is a key environmental toxicant having significant impacts on human health. Millions of people in developing countries such as Bangladesh, Mexico, Taiwan, and India are affected by arsenic contamination through groundwater. Environmental contamination of arsenic leads to leads to various types of cancers, coronary and neurological ailments in human. There are several sources of arsenic exposure such as drinking water, diet, wood preservatives, smoking, air and cosmetics, while, drinking water is the most explored route. Inorganic arsenic exhibits higher levels of toxicity compared its organic forms. Exposure to inorganic arsenic is known to cause major neurological effects such as cytotoxicity, chromosomal aberration, damage to cellular DNA and genotoxicity. On the other hand, long-term exposure to arsenic may cause neurobehavioral effects in the juvenile stage, which may have detrimental effects in the later stages of life. Thus, it is important to understand the toxicology and underlying molecular mechanism of arsenic which will help to mitigate its detrimental effects. The present review focuses on the epidemiology, and the toxic mechanisms responsible for arsenic induced neurobehavioral diseases, including strategies for its management from water, community and household premises. The review also provides a critical analysis of epigenetic and transgenerational modifications, mitochondrial oxidative stress, molecular mechanisms of arsenic-induced oxidative stress, and neuronal dysfunction.

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Section: Neuronal Effects Of Arsenicmentioning

confidence: 99%

Molecular Mechanism of Arsenic-Induced Neurotoxicity including Neuronal Dysfunctions

Thakur

Rachamalla

Niyogi

et al. 2021

IJMS

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“…To achieve the precision of data, the arsenic levels in groundwater, fingernails, standard solutions (standard solution Fluka-51844, Sigma–Aldrich, Switzerland), and blank samples were examined in triplicate. In all repeated measurements, a relative standard deviation of 5–10% was achieved during the experiments 3 , 24 . Furthermore, to further verify the results, no human fingernail-certified reference material was available for comparison.…”

Section: Methodsmentioning

confidence: 95%

“…This metalloid recognized as a human carcinogen by the International Agency for Research on Cancer (IARC) and the United States Environmental Protection Agency (USEPA) is found in organic and inorganic forms and with different oxidation states (− 3, 0, + 3, + 5) in the environment 6 , 7 . Non-occupational exposure to inorganic arsenic (arsenite and arsenate) through the consumption of drinking water sources causes carcinogenic and non-carcinogenic health effects in the exposed human population 3 , 8 , 9 . Acute and chronic human health effects of arsenic exposure include skin lesions, cardiovascular disease, anemia, renal impairment, as well as respiratory disorders, and different types of cancers (lung, skin, liver, kidney, and bladder) 10 – 12 .…”

Section: Introductionmentioning

confidence: 99%

Application of fingernail samples as a biomarker for human exposure to arsenic-contaminated drinking waters

Shokoohi

Khazaei

Karami

et al. 2022

Sci Rep

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This study evaluated the relationship between arsenic uptake via drinking water ingestion and arsenic concentration in fingernails as a biomarker for human exposure. For this purpose, we collected fingernail samples from 40 healthy participants of arsenic-affected rural regions of Kaboudrahang County, the west of Iran. A total of 49 fingernail samples were also collected from individuals who lived in areas where contamination of drinking water sources with arsenic had not been reported. It was found that the fingernails arsenic contents in 50 and 4.08% of the samples collected from arsenic-contaminated and reference villages were higher than the normal arsenic values of nails (0.43–1.08 µg/g), respectively. Based on the results of adjusted multiple linear regression, a significant association was found between groundwater and fingernails arsenic concentration (p < 0.001). Moreover, a statistically significant association was shown between arsenic in the fingernail samples and gender (p = 0.037). Fingernails arsenic contents were not significantly affected by other variables including age, smoking habits, and BMI (p > 0.05). In light of the results of this study, the use of biological indicators such as fingernail tissues due to easier sampling and less risk of external contamination is suitable for assessing exposure to heavy metals in contaminated areas.

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“…It was noted that prolonged consumption of arsenic-containing water could lead to severe health conditions in humans, including arsenicosis, cardiovascular disease, diabetes, and cancer. (Rahaman et al, 2021;Shokoohi et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Understanding the adsorption of iron oxide nanomaterials in magnetite and bimetallic form for the removal of arsenic from water

Boruah

Tyagi²,

Gupta³

et al. 2023

Front. Environ. Sci.

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Arsenic decontamination is a major worldwide concern as prolonged exposure to arsenic (>10 µg L-1) through drinking water causes serious health hazards in human beings. The selection of significant, cost-effective, and affordable processes for arsenic removal is the need of the hour. For the last decades, iron-oxide nanomaterials (either in the magnetite or bimetallic form) based adsorptive process gained attention owing to their high arsenic removal efficiency and high regenerative capacity as well as low yield of harmful by-products. In the current state-of-the-art, a comprehensive literature review was conducted focused on the applicability of iron-based nanomaterials for arsenic removal by considering three main factors: (a) compilation of arsenic removal efficiency, (b) identifying factors that are majorly affecting the process of arsenic adsorption and needs further investigation, and (c) regeneration capacity of adsorbents without affecting the removal process. The results revealed that magnetite and bimetallic nanomaterials are more effective for removing Arsenic (III) and Arsenic (V). Further, magnetite-based nanomaterials could be used up to five to six reuse cycles, whereas this value varied from three to six reuse cycles for bimetallic ones. However, most of the literature was based on laboratory findings using decided protocols and sophisticated instruments. It cannot be replicated under natural aquatic settings in the occurrence of organic contents, fluctuating pH and temperature, and interfering compounds. The primary rationale behind this study is to provide a comparative picture of arsenic removal through different iron-oxide nanomaterials (last twelve yearsof published literature) and insights into future research directions.

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The relationship between chronic exposure to arsenic through drinking water and hearing function in exposed population aged 10–49 years: A cross-sectional study

Cited by 13 publications

References 32 publications

Molecular Mechanism of Arsenic-Induced Neurotoxicity including Neuronal Dysfunctions

Molecular Mechanism of Arsenic-Induced Neurotoxicity including Neuronal Dysfunctions

Application of fingernail samples as a biomarker for human exposure to arsenic-contaminated drinking waters

Understanding the adsorption of iron oxide nanomaterials in magnetite and bimetallic form for the removal of arsenic from water

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