The Relationship Between Bispectral Index and Electroencephalographic Parameters During Isoflurane Anesthesia

Morimoto, Yasuhiro; Hagihira, Satoshi; Koizumi, Yumika; Ishida, Kazuyoshi; Matsumoto, Mishiya; Sakabe, Takefumi

doi:10.1213/01.ane.0000105867.17108.b6

Cited by 96 publications

(79 citation statements)

References 11 publications

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“…Poorer correlations between BIS and relative beta ratio in our study would result from the narrower range of these parameters in comparison to those that occur during anesthesia with other agents, such as isoflurane [14]. In contrast to the unchanged BIS, relative beta ratio, and SEF95 within 60 min after the induction of anesthesia, the spectral power density in the beta-band was highest at 5 min, decreasing thereafter but remaining higher than the baseline levels at 60 min.…”

Section: Discussioncontrasting

confidence: 69%

“…The spectral power analysis was performed on the EEG waves obtained for a period of 1 min commencing with each time point of blood sampling. The relative beta ratio at the same time point was calculated following the equation [14]: log 10 [spectral power (30-47 Hz)/spectral power (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)]. The EEG analysis was performed by one of the authors (W.M.)…”

Section: Analysis Of Eegmentioning

confidence: 99%

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Electroencephalographic response following midazolam-induced general anesthesia: relationship to plasma and effect-site midazolam concentrations

et al. 2010

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Section: Discussioncontrasting

confidence: 69%

Section: Analysis Of Eegmentioning

confidence: 99%

Electroencephalographic response following midazolam-induced general anesthesia: relationship to plasma and effect-site midazolam concentrations

et al. 2010

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“…Hypothermia may be the principal reason for the lower values of RE and SE, but it is well known that low temperatures reduce consciousness and EEG activity, which may be expressed in the observed lower RE and SE values. The BSR is stated to be a reliable parameter to estimate the intensity of suppression of electrical brain activity [21] and it is one electroencephalographic component of the algorithm of the BIS [22].…”

Section: Discussionmentioning

confidence: 99%

Comparison of Spectral Entropy and Bispectral Index Electroencephalography in Coronary Artery Bypass Graft Surgery

Baulig

Seifert

Schmid

et al. 2010

Journal of Cardiothoracic and Vascular Anesthesia

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Objective: The study's aim was to compare Response (RE) and State Entropy (SE) with Bispectral Index (BIS) electroencephalography (EEG) as an alternative cerebral monitoring tool in patients scheduled for coronary artery bypass graft surgery.Design: Prospective, observational single-center study Setting: University HospitalParticipants: Thirty patients undergoing coronary artery bypass graft surgery receiving remifentanil-propofol anaesthesia.Interventions Surgery was performed with cardiopulmonary bypass (CPB) and cardiac arrest in fifteen patients, with CPB without cardiac arrest in nine patients and without CPB in six patients. Measurements and Main results RE, SE, BIS, burst suppression ratio (BSR) and frontalelectromyography (f-EMG) were detected simultaneously. RE and SE compared favorably to BIS and their correlations were strong (r 2 = 0.6, r 2 = 0.55, respectively). Mean bias of RE and BIS was -1.8, but limits of agreement were high (+20.5/-24.1). RE and SE tended to be lower than the BIS values in the CPB subgroups. Detection of BSR was similar with RE and SE, and the BIS. A strong correlation existed between BIS and f-EMG (r 2 = 0.62), in contrast to RE (r 2 = 0.45) and SE (r 2 =0.39). BIS monitoring was significantly more disturbed than RE and SE with 9.1 ±10.9% and 0.1±0.2% of the total anesthesia time, respectively. Neither implicit nor explicit memory was demonstrated.Conclusion RE and SE are comparable with the BIS but showed significantly less interference from f-EMG and superior resistance against artefacts. Thus, Spectral Entropy is more suitable than the BIS during propfol-remifentanil anesthesia in cardiac surgery patients. Words: 2482

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“…26 Blood volume losses, greater than 20% would be needed to cause sinus tachycardia and a decrease in blood pressure. 27,28 A limitation of this study is that no specific equipment was used to monitor the depth of anesthesia (BIS), and also the possible correlation with the control of hemodynamic disorders caused by nociceptive stimuli (29)(30)(31)(32)(33).…”

Section: Discussionmentioning

confidence: 99%

Dexmedetomidine in anesthesia of children submitted to videolaparoscopic appendectomy: a double-blind, randomized and placebo-controlled study

Smania¹,

Piva²,

García³

2008

Rev. Assoc. Med. Bras.

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SUMMARY OBJECTIVES.To evaluate the hemodynamic responses to nociceptive stimuli in children submitted to videolaparoscopic appendectomy under balanced anesthesia with isoflurane and dexmedetomidine. METHODS. Randomized, double-blind and placebo-controlled study involving 26 children submitted to videolaparoscopic appendectomy carried out at Hospital São Lucas (PUCRS) between May 2004 and February 2005. Patients were assigned to two groups: (a) Dexmedetomidine group (n=13): infusion of 1μg/kg over 10 minutes and maintenance dose of 0.5μg/kg/ h) as an adjuvant to inhaled isoflurane anesthesia; (b) Control group (n=13): normal saline infusion at a similar rate and volume of the dexmedetomidine infusion. During the different surgical and anesthetic periods, groups were compared regarding heart rate, systolic and diastolic arterial blood pressures as well as need of supplemental fentanyl infusion. Student's t test, ANOVA, and Finner's procedure were used for statistical analysis. RESULTS. During the strongest nociceptive stimuli (airway access and abdominal catheter placement), the heart rate and systolic blood pressure increased significantly (p<0.001) in the control group compared to the dexmedetomidine group. Compared to baseline levels, the hemodynamic responses to nociceptive stimuli were more stable when dexmedetomidine was used in combination with inhaled isoflurane anesthesia. The need for supplemental doses of fentanyl and the hemodynamic parameters were similar for both groups. CONCLUSION. Dexmedetomidine combined with inhaled isoflurane for anesthesia of children submitted to videolaparoscopic appendectomy, efficiently blocks the hemodynamic responses to nociceptive stimuli. When compared to placebo, the use of dexmedetomidine did not change the need for supplemental doses of fentanyl for maintenance of hemodynamic parameters during the intraoperative period.

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The Relationship Between Bispectral Index and Electroencephalographic Parameters During Isoflurane Anesthesia

Cited by 96 publications

References 11 publications

Electroencephalographic response following midazolam-induced general anesthesia: relationship to plasma and effect-site midazolam concentrations

Electroencephalographic response following midazolam-induced general anesthesia: relationship to plasma and effect-site midazolam concentrations

Comparison of Spectral Entropy and Bispectral Index Electroencephalography in Coronary Artery Bypass Graft Surgery

Dexmedetomidine in anesthesia of children submitted to videolaparoscopic appendectomy: a double-blind, randomized and placebo-controlled study

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