The relationship between adherence to the Mediterranean diet and the severity and short-term prognosis of acute coronary syndromes (ACS): The Greek Study of ACS (The GREECS)

Panagiotakos, Demosthenes B.; Arapi, Sophia; Pitsavos, Christos; Antonoulas, Antonis; Mantas, Yannis; Zombolos, Spyros; Stefanadis, Christodoulos

doi:10.1016/j.nut.2006.04.005

Cited by 22 publications

(7 citation statements)

References 29 publications

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“…A modified version of this score, in which monounsaturated fats are replaced by all unsaturated fats, has been suggested to make its application more suitable to countries in which olive oil is not the main source of unsaturated fatty acids. Healthy dietary patterns, and in particular the Mediterranean diet, has been explored with regard to cardiovascular disease outcomes (Martinez-Gonzalez et al, 2002;WHO Technical Report Series, 2003;Panagiotakos et al, 2006;Willett, 2006). Less is known about how these patterns relate to risk of cancer (de Lorgeril et al, 1998;Fung et al, 2005;Cottet et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

Does the Mediterranean dietary pattern or the Healthy Diet Index influence the risk of breast cancer in a large British cohort of women?

et al. 2011

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Background/Objective: To assess the risk of developing breast cancer associated with consumption of two common dietary patterns: a Mediterranean dietary pattern and a dietary pattern, which conforms to the World Health Organization Healthy Diet Index (WHO HDI). Subjects/Methods: Dietary data from a 217-item food frequency questionnaire were used to generate two dietary patterns according to pre-defined criteria in women from the UK Women's Cohort Study. Survival analysis using Cox regression was used to estimate hazards ratios for risk of breast cancer adjusted for known confounders.Results: This analysis included 828 incident cases of breast cancer in 33 731 women with a mean follow-up of 9 years. There were no statistically significant associations between either the Mediterranean dietary pattern or the WHO HDI and risk of breast cancer. In premenopausal women, there was a nonsignificant trend suggesting that increasing compliance with the Mediterranean diet was associated with lower risk of breast cancer. Maximal adherence to the Mediterranean diet was associated with hazards ratio ¼ 0.65 (95% confidence interval: 0.42-1.02, P trend ¼ 0.09) compared with minimal adherence. In postmenopausal women, no clear trends were observed. Conclusions: In this study, no strong association between the risk of breast cancer and the consumption of either a Mediterranean-type diet or one characterized by adherence to the WHO HDI was observed. In premenopausal, but not postmenopausal women, there was a nonsignificant inverse association with increasing adherence to the Mediterranean diet pattern.

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Section: Discussionmentioning

confidence: 99%

Does the Mediterranean dietary pattern or the Healthy Diet Index influence the risk of breast cancer in a large British cohort of women?

et al. 2011

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“…Indeed, the findings were impressive demonstrating a 50% to 70% lower risk of recurrent heart disease events among subjects who followed the intervention dietary pattern. In line with the Lyon Heart Study, the GREECS observational study in the short-term and up to 1-year follow-up revealed that ACS patients who followed a dietary pattern close to the Mediterranean experienced lower risk of recurrent cardiac events (11). Within the framework of the European Perspective In Cancer (EPIC) project, the investigators, pointed out that the association between Mediterranean diet and mortality was about 5 times stronger among coronary patients as compared to healthy individuals (12).…”

Section: Mediterranean Diet and Secondary Acs Preventionmentioning

confidence: 60%

Secondary Prevention of Acute Coronary Syndrome. Socio-economic and Lifestyle Determinants: A Literature Review

Notara¹,

Panagiotakos²,

Pitsavos³

2014

Cent Eur J Public Health

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Although cardiovascular disease mortality rates seem to decline, especially among middle-aged people in developed countries, the prevalence of acute coronary syndrome (ACS) increases, representing the most common cause of morbidity in both developed and developing countries and generating large economic burden. It is estimated that one fifth of the ACS patients die suddenly and half of them belong to a fast growing popula- tion age-group, i.e., those between 70 and .80 years. A substantial number of these deaths has been attributed to various lifestyles, modifiable factors; therefore, it can be prevented. However, factors such as dietary habits and behaviours, physical activity, life stress and smoking habits, although thoroughly discussed, are not well understood and appreciated in the spectrum of secondary ACS prevention. The latter deserves further attention under the prism of socio-economic status that has changed dramatically in the last years in some populations. The aim of this review was to discuss the role of lifestyle factors on secondary ACS prevention under the prism of individual's socio-economic status. Based on the retrieved information it was revealed that there is vast evidence that secondary prevention of cardiovascular events cannot be accomplished simply through medical treatment, but it requires a multifaceted approach incorporating lifestyle modifications, too. Therefore, public health policy endeavours should be directed towards multifocal strategies, i.e., to motivate and support cardiac patients to consistently follow treatment regimens and to establish more effective and efficient community lifestyle interventions.

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“…All participants were asked to report the average intake (per week or day) of several food items that they consumed (during the last 12 months). The Med-DietScore was also applied to evaluate adherence to the Mediterranean diet (Panagiotakos et al 2006a). In brief, MedDietScore is a 11-item diet index which is based on the rationale of the Mediterranean diet pyramid; values from 0 to 5 were assigned to frequency of consumption of food groups presumed to be in accordance with the Mediterranean diet (i.e.…”

Section: Baseline Measurementsmentioning

confidence: 99%

Education status determines 10-year (2002-2012) survival from cardiovascular disease in Athens metropolitan area: the ATTICA study, Greece

Panagiotakos

Georgousopoulou

Notara

et al. 2015

Health Soc Care Community

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Cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide, and educational level seems to be an important determinant of the disease occurrence. The aim of this work was to investigate the association between education status and 10-year incidence of CVD, controlling for various socio-demographic lifestyle and clinical factors. From May 2001 to December 2002, 1514 men and 1528 women (>18 years) without any clinical evidence of CVD or any other chronic disease, at baseline, living in greater Athens area, Greece, were enrolled. In 2011-2012, the 10-year follow-up was performed in 2583 participants (15% of the participants were lost to follow-up). Incidence of fatal or non-fatal CVD was defined according to WHO-ICD-10 criteria. Education status was measured in years of schooling. The 10-year incidence of CVD was 15.7% [95% confidence intervals (CI) 14.1%-17.4%], 19.7% in men and 11.7% in women (Pgender < 0.001). Age-and gender-adjusted analyses revealed that those with low education (<9 years of schooling) were 1.52 times more likely (95% CI 1.03-2.23%) to have CVD compared with those with high education (>12 years of schooling). People in the low education group had higher prevalence of hypertension, diabetes and dyslipidaemias, were more likely to be smokers and sedentary, had less healthy dietary habits, as compared with those in the high education group. When controlling for participants' medical history, smoking, dietary and lifestyle habits, low education was no longer significantly associated with CVD, illustrating the mediating effect of clinical and behavioural factors in the link between education and disease. It was of interest that low education status interacted with alcohol drinking, enhancing the adverse effect of low education on CVD risk (relative risk 1.44, 95% CI 0.94%-2.20%), after various adjustments made. In this study, it was concluded that low educational level was associated with increased CVD risk. This was mainly explained by the intermediate association of low education with unhealthy choices that consequently worsen clinical status.

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The relationship between adherence to the Mediterranean diet and the severity and short-term prognosis of acute coronary syndromes (ACS): The Greek Study of ACS (The GREECS)

Cited by 22 publications

References 29 publications

Does the Mediterranean dietary pattern or the Healthy Diet Index influence the risk of breast cancer in a large British cohort of women?

Does the Mediterranean dietary pattern or the Healthy Diet Index influence the risk of breast cancer in a large British cohort of women?

Secondary Prevention of Acute Coronary Syndrome. Socio-economic and Lifestyle Determinants: A Literature Review

Education status determines 10-year (2002-2012) survival from cardiovascular disease in Athens metropolitan area: the ATTICA study, Greece

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