The Relationship between ABO Blood Group and Glioblastoma Multiforme

Akca, Zeki; Mutlu, Hasan; Erden, Abdülsamet; Büyükçelik, Abdullah; Sezer, Emel; İnal, Ali̇

doi:10.5455/medscience.2014.03.8160

Cited by 5 publications

(6 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“… 7 Previously, many different results have been reported in other cancer types. 8 The association of ABO blood groups with diabetes mellitus has been observed earlier in several epidemiological and genetic studies and resulted with inconsistent findings. 7 No association has been observed between essential HT and ABO blood groups in a study, while another study showed that the blood group B was seen more in the HT and obesity.…”

Section: Introductionmentioning

confidence: 99%

Are the blood groups of women with preeclampsia a risk factor for the development of hypertension postpartum?

Avcı¹,

Karagöz²,

Ozer³

et al. 2016

TCRM

Self Cite

View full text Add to dashboard Cite

IntroductionPreeclampsia (PE) is a pregnancy-related disorder characterized by hypertension (HT) and proteinuria noticeable after 20 weeks of gestation. PE is now considered as a cardiovascular disease risk factor and a number of studies have shown that experiencing PE increases the prevalence of various cardiovascular risk factors, such as metabolic syndrome and HT. In this study, we aimed to investigate any possible relationship between the ABO/Rh blood group system and PE in Turkey. In the second part of the study, we examined the relationship between the ABO blood group system and development of HT after PE.Patients and methodsA total of 250 patients with PE from Kayseri Training and Research Hospital between 2002 and 2012 were included in the study. Patients were classified according to blood groups (A, B, AB, and O) and Rh status (+/−).ResultsThere was a significant difference between the patients with PE and the control group in terms of distribution of ABO blood groups and the percentage of group AB was found to be higher in patients with PE compared to the control group (P=0.029). The risk of developing PE was significantly higher in group AB than other blood groups (P=0.006). The risk of developing HT after PE was significantly higher in group O than other blood groups (P=0.004).DiscussionIn this study, we found that the patients with blood group AB have a higher risk for PE. The patients with PE of blood group O are at high risk of developing HT, and Rh factor was identified as another risk at this point and these patients should be closely followed postpartum.

show abstract

Section: Introductionmentioning

confidence: 99%

Are the blood groups of women with preeclampsia a risk factor for the development of hypertension postpartum?

Avcı¹,

Karagöz²,

Ozer³

et al. 2016

TCRM

Self Cite

View full text Add to dashboard Cite

show abstract

“…On the contrary, in a case-control study, Akca et al, aimed to compare the patients with glioblastoma multiforme with control groups regarding ABO blood groups. On the basis of the study results, no significant differences among O, A, B and AB blood groups were shown [24]. In a study conducted by Turowski and Czochra, the analysis was based on the distribution of ABO blood groups in 271 patients treated for glioblastoma multiforme (GBM), whereas the control group included 500 patents with craniocerebral trauma.…”

Section: The Influence Of Abo Blood Group On the Development Of Gliomamentioning

confidence: 98%

“…Furthermore, several studies have shown conflicting results concerning the relationship between ABO blood groups and glioma risk [16][17][18][19][20][21][22][23][24][25][26][27][28][29]. Finally, differences are observed not only in the distribution of ABO blood group antigens among patients with primary brain tumors in various countries worldwide, but also among different ethnic groups within the country.…”

Section: Introductionmentioning

confidence: 99%

ABO Blood Groups and Risk of Glioma

Arsic¹

2022

Blood Groups - More Than Inheritance of Antigenic Substances

View full text Add to dashboard Cite

Gliomas are one of the most common primary brain tumors and the etiology of gliomas remains unknown in most cases. The aim of this case–control study was to investigate possible association between incidence in relation to glioma and certain blood groups. This study included 100 histopathologically verified cases of glioma and 200 age and sex-matched controls without malignant diseases that were admitted to the same hospital. The results revealed that the patients with group AB were at 3.5-fold increased risk of developing glioma compared to the patients with other ABO blood groups. In this particular study, there was more male patients with glioma with the blood group AB. However, mechanisms that explain the relationship between the blood groups ABO and a cancer risk are unclear. Several hypotheses have been proposed, including the one with a modulatory role of blood group ABO antigens. In addition, the blood group ABO system regulates the level of circulating proinflammatory and adhesion molecules which play a significant role in the tumorigenesis process. Additionally, the recent discovery that includes the von Willebrand factor (vWF) as an important modulator of angiogenesis and apoptosis provides one plausible explanation as regards the role of the blood group ABO in the tumorigenesis process. To our knowledge, this is the first study that examined the relationship of blood group in patients diagnosed with glioma among the Serbian population. Moreover, for the first time our study results suggested that blood group AB increased the risk of glioma. The results of this study suggested that the blood group AB could be one of hereditary factors which had an influence on the occurrence of glioma. The further research is needed on a larger sample, to confirm these findings and the possible mechanisms by which the ABO system contributes to the pathology of glioma.

show abstract

“…In glioblastoma multiforme, one study found no association, whereas another revealed an independent poor prognostic value for non-O blood groups. 26,27 Due to inconsistency and lack of any study over ABO blood groups effect over pediatric brain tumors, our current study aims to investigate the relationship between ABO blood groups and brain tumor incidence in the Jordanian pediatric population in a casecontrolled manner.…”

Section: Introductionmentioning

confidence: 99%

AB Blood Group Confers Higher Risk for Primary Brain Tumors in Pediatrics

Shudifat¹,

Suqi²,

Soub³

et al. 2021

RMHP

View full text Add to dashboard Cite

Purpose Our current study investigates the relationship between ABO blood groups and brain tumor incidence in the Jordanian pediatric population in a case-controlled manner. Patients and Methods This case-control study targeted pediatric primary brain tumor patients and tumor-free controls. Cases included patients younger than 18 when given a histologically confirmed diagnosis with a primary brain tumor, ascertained from two tertiary hospitals in Jordan. Controls were age- and gender-matched to cases and acquired from JUH pediatric clinics, with an exclusion for all patients with a personal history of tumors. Through using available records and calling guardians, our team obtained patients’ and controls’ blood groups. Results Our case control included 81 (35.4%) pediatric primary brain tumor patients and age- and gender-matched tumor-free controls 148 (64.6%). When compared to O blood group, patients with A and B blood groups were not at higher risk of developing pediatric primary brain tumors (P=0.742, P=1.000, respectively). However, Chi-square analysis revealed a 2.79-fold higher risk for pediatric primary brain tumors in AB blood group patients (P=0.024). Gender-specific analysis revealed a 3.42-fold higher risk for pediatric brain tumors in AB blood group males when compared to O blood group males. Conclusion This work represents the first published study on the association between blood groups and pediatric brain tumors. With future research with larger samples and control of confounding factors, AB blood group may become a more established risk factor for pediatric brain tumors, aiding in screening.

show abstract

The Relationship between ABO Blood Group and Glioblastoma Multiforme

Abstract: Glioblastoma Multiforme (GBM) is the most common type of primary brain tumor and its prognosis is poor. Some studies have investigated the relationship between ABO Blood

Cited by 5 publications

References 19 publications

Are the blood groups of women with preeclampsia a risk factor for the development of hypertension postpartum?

Are the blood groups of women with preeclampsia a risk factor for the development of hypertension postpartum?

ABO Blood Groups and Risk of Glioma

AB Blood Group Confers Higher Risk for Primary Brain Tumors in Pediatrics

Contact Info

Product

Resources

About