The Relation of Impaired Fasting Glucose and HDL-Cholesterol by Gender and Body Mass Index

Abstract

Objectives: We investigated relation between HDL-cholesterol and the incidence of impaired fasting glucose in obese and normal body weight by gender in Korean adults. Methods: 6,438 subjects aged 40-59 years (2,197 impaired fasting glucose, 4,241 normoglycemia) were selected except the patients with cardiovascular disease and pregnant women using 2016 KNHANES data. We analyzed the relation of impaired fasting glucose and HDLcholesterol by BMI. Results: In both men and women regardless of BMI, who with low HDL-cholesterol significantly higher risk of impaired fasting glucose than who with normal HDL-cholesterol in unadjusted model. In except men with obesity, who with low HDL-cholesterol significantly higher risk of impaired fasting glucose than who with normal HDL-cholesterol when age, smoke, drink, exercise adjusted. In addition, women with normal BMI (OR, 1.82; 95% CI, 1.42-2.33) higher risk of impaired fasting glucose than women with obesity (OR, 1.57; 95% CI, 1.14-2.17). Conclusions: It is necessary to management of HDL-cholesterol to control impaired fasting glucose, except for obese men.

Relating Factors for Impaired Fasting Glucose in Korean Adult: A Population Based Study

“…The results of this study indicate that IFG prevalence was high in male subjects who were employed. This result is similar to the general characteristics of individuals with IFG as found in a previous study [5], and is also similar to the results of a study that showed Korean o ce workers as having various health problems such as diabetes mellitus due to a lack of exercise, poor eating habits, and drinking and smoking [34]. Although the legal working hours per week in South Korea were shortened with the introduction of the 5-day workweek system in 2004, South Korea continues to have the longest work hours in the world [35].…”

“…Fasting blood glucose levels and obesity are affected by balanced caloric intake rather than daily caloric intake [26]. In addition, the outcome of body mass index (BMI) control through dietary intake and physical activity affects IFG [5]; thus, it is important to choose a balanced diet. Western countries are using strategies to improve individuals' health literacy for managing their blood glucose and utilizing nutritional information on various foods [27,28].…”

“…In this study, 76.1% of subjects with IFG were found to be obese (BMI > 23 kg/m 2 ). Since there was a very high correlation between an increase in BMI and the prevalence of diabetes mellitus and IFG [5], exercise and healthy eating habits for BMI control are considered important. However, our study found that "walking for 150 minutes or more per week" did not have a signi cant effect on IFG prevalence.…”

“…Of concern for individuals with IFG is not only a higher likelihood of developing diabetes, but also a greater risk of developing cardiovascular disease [4]. Persons with IFG have a higher body mass index (BMI), higher blood pressure, higher obesity rate, lower HDL cholesterol, and a higher level of triglycerides compared to normoglycemic individuals [5]. Although healthcare providers emphasize the importance of changing one's lifestyle to prevent diabetes [6], individuals with IFG are nevertheless at risk of engaging in unhealthy eating habits, smoking, and the consumption of alcohol [5].…”

“…A previous study showed that in addition to health literacy, age, gender, obesity, and health behaviors were signi cant factors associated with IFG [5,17]. However, there is a lack of clarity regarding the relationship between health literacy and the factors affecting IFG.…”