Abstract:The observation that both acids and alkalies cause swelling in excised muscles, and that this swelling is suppressed by the addition of neutral salts, is no new one. The pernicious influence of acids on muscle is referred to as a commonplace by Ringer in 1883 (20, 21) and quantitative data of both acid and alkaline swelling are given by Loeb in 1897 (11). Nevertheless, the subject has never yet received systematic investigation at the hands of any one worker. The following record of experiments showing the beh… Show more
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