The Relation of Body Mass Index to Asthma, Chronic Bronchitis, and Emphysema

Guerra, Stefano; Sherrill, Duane L.; Bobadilla, Arnel; Martínez, Fernando D.; Barbee, Robert A.

doi:10.1378/chest.122.4.1256

Cited by 301 publications

(240 citation statements)

References 25 publications

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“…It is interesting that patients with the CB phenotype showed a lower BMI in our study, which was inconsistent with previous studies in which CB phenotype was associated with higher BMI and emphysematous phenotype was associated with lower BMI (31,32). The reason was not clear.…”

Section: Discussioncontrasting

confidence: 99%

Chronic bronchitis is associated with severe exacerbation and prolonged recovery period in Chinese patients with COPD: a multicenter cross-sectional study

Liang

Chen

et al. 2017

J. Thorac. Dis.

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Section: Discussioncontrasting

confidence: 99%

Chronic bronchitis is associated with severe exacerbation and prolonged recovery period in Chinese patients with COPD: a multicenter cross-sectional study

Liang

Chen

et al. 2017

J. Thorac. Dis.

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“…They can be considered natural candidates for specialized physical guidance, especially when selected for operation, for several reasons including to enhance recovery and prevent perioperative complications, such as pneumonia and atelectasis, 5,6 and also to promote fitness and improved quality of life coincident with postoperative weight loss.…”

Section: Discussionmentioning

confidence: 99%

“…5 Both daytime and especially nocturnal neurophysiology may be impaired in association with obstructive sleep apnea. The tendency toward gastroesophageal reflux because of high intra-abdominal pressure along with hypoventilation may trigger various derangements; chronic bronchitis 6 and asthma 7,8 are not unusual; and after surgical operations, atelectasis is relatively common. 9 Although asthma may be prominent in this setting and notably improves after bariatric treatment, 7 respiratory insufficiency in the obese is mostly classified as restrictive.…”

mentioning

confidence: 99%

Pulmonary function and aerobic capacity in asymptomatic bariatric candidates with very severe morbid obesity

et al. 2004

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PURPOSE:Aerobic capacity and respiratory function may be compromised in obesity, but few studies have been done in highly obese bariatric candidates. In a prospective study, these variables were documented in the preoperative period, aiming to define possible physiologic limitations in a apparently healthy and asymptomatic population.METHOD: Forty-six consecutively enrolled adults (age 39.6 ± 8.4 years, 87.0% females, body mass index /BMI 49.6 ± 6.3 kg/m 2 ) were analyzed. Ventilatory variables were investigated by automated spirometry, aerobic capacity was estimated by a modified Bruce test in an ergometric treadmill, and body composition was determined by bioimpedance analysis.RESULTS: Total fat was greatly increased (46.4 ± 4.6% of body weight) and body water reduced (47.3 ± 4.6 % body weight), as expected for such obese group. Spirometric findings including forced vital capacity of 3.3 ± 0.8 L and forced expiratory volume-1 second of 2.6 ± 0.6 L were usually acceptable for age and gender, but mild restrictive pulmonary insufficiency was diagnosed in 20.9%. Aerobic capacity was more markedly diminished, as reflected by very modest maximal time (4.5 ± 1.1 min) and distance (322 ±142 m) along with proportionally elevated maximal oxygen consumption (23.4 ± 9.5 mL/kg/min) achieved by these subjects during test exercise.CONCLUSIONS: 1) Cardiopulmonary evaluation was feasible and well-tolerated in this severely obese population; 2) Mean spirometric variables were not diminished in this study, but part of the population displayed mild restrictive changes; 3) Exercise tolerance was very negatively influenced by obesity, resulting in reduced endurance and excessive metabolic cost for the treadmill run; 4) More attention to fitness and aerobic capacity is recommended for seriously obese bariatric candidates;

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“…[11][12][13][14][15][16] However, most longitudinal studies linking obesity and the development of asthma or asthma-like symptoms have been in adults. [17][18][19][20] One longitudinal study in children, by CastroRodriguez et al, analyzing results of the Tucson Children's Respiratory Study, is limited by smaller numbers and the non-national data sample. 18 Another study found an effect in boys, but not in girls.…”

Section: Introductionmentioning

confidence: 99%

Boys with high body masses have an increased risk of developing asthma: findings from the National Longitudinal Survey of Youth (NLSY)

et al. 2005

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Objective: To determine the relation between body mass index and the development of asthma in children. Design: Prospective study of 4393 asthma-free children followed for up to 14 years. Setting: Children of participants in the National Longitudinal Survey of Youth. Methods: Analysis was limited to children who were followed from birth and were asthma-free during the first 24 months of life. The outcome was the development of asthma during follow-up (incident asthma). Body mass index (BMI) was our main predictor of interest. Survival analyses, using time to development of asthma as the main endpoint, were stratified by sex and controlled for race/ethnicity, poverty status, and prenatal maternal smoking. Results: Asthma developed in 218 (5.0 %) children during the follow-up period. The relation between BMI and incident asthma varied by sex. A BMI X85th percentile at age 2-3 years was a risk factor for subsequent asthma development in boys (hazard ratio (HR) 1.6 95% confidence interval (CI) 1.1, 2.4) but not girls (HR 0.8, 95% CI 0.5, 1.4). Similarly, boys with BMIs always X85th percentile were at increased risk for subsequent asthma development (HR 2.4, 95% CI 1.4, 4.4) but not girls (HR 1.5, 95% CI 0.7, 2.9). Conclusion: Boys with high body masses may be at an increased risk for developing asthma.

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The Relation of Body Mass Index to Asthma, Chronic Bronchitis, and Emphysema

Cited by 301 publications

References 25 publications

Chronic bronchitis is associated with severe exacerbation and prolonged recovery period in Chinese patients with COPD: a multicenter cross-sectional study

Chronic bronchitis is associated with severe exacerbation and prolonged recovery period in Chinese patients with COPD: a multicenter cross-sectional study

Pulmonary function and aerobic capacity in asymptomatic bariatric candidates with very severe morbid obesity

Boys with high body masses have an increased risk of developing asthma: findings from the National Longitudinal Survey of Youth (NLSY)

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