The relation between zoledronic acid infusion and interbody fusion in patients undergoing transforaminal lumbar interbody fusion surgery

Li, Chao; Wang, Hui-Ren; Li, Xilei; Zhao, Xiaogang; Dong, Jian

doi:10.1007/s00701-012-1283-7

Cited by 40 publications

(48 citation statements)

References 23 publications

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“…Figure 1 illustrates the process of study selection. Ten trials [25][26][27][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46] were finally designed to evaluate the effect of the timing of BP initiation after surgery for fracture healing and fulfilled the inclusion criteria for published studies (including safety reports), including a large-scale multicultural RCT with a large number of reports written about it [26,27,[38][39][40][41][42][43][44][45][46].…”

Section: Resultsmentioning

confidence: 99%

“…Regarding sex, 22.4 % (n=646) [29,31,37], five trials were hip fracture [27,30,34,35,37,47], and one trial included spinal fractures [25]. The overall mean age was 74.2 years.…”

Section: Patient Characteristicsmentioning

confidence: 99%

“…Some case reports suggest that a potential complication of long-term BP therapy may be a delay in fracture healing in humans [22][23][24]. A case control study reported that BP use in the post-fracture period was associated with an increased probability of nonunion (odds ratio [OR] 2.37, 95 % confidence interval [CI] 1.13 to 4.96) [25].…”

Section: Introductionmentioning

confidence: 99%

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Timing of the initiation of bisphosphonates after surgery for fracture healing: a systematic review and meta-analysis of randomized controlled trials

Cai

Zhang

2014

Osteoporos Int

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Section: Resultsmentioning

confidence: 99%

“…Regarding sex, 22.4 % (n=646) [29,31,37], five trials were hip fracture [27,30,34,35,37,47], and one trial included spinal fractures [25]. The overall mean age was 74.2 years.…”

Section: Patient Characteristicsmentioning

confidence: 99%

See 1 more Smart Citation

Timing of the initiation of bisphosphonates after surgery for fracture healing: a systematic review and meta-analysis of randomized controlled trials

Cai

Zhang

2014

Osteoporos Int

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“…This observation can partially be explained by normal ageing (Maldonado et al, 2011) but can also be directly linked to the surgical intervention and the mechanical stresses that are subsequently generated (Matsumoto et al, 2010). Moreover, spinal fusion does not always succeed and an incomplete fusion might result in the reappearance of back pain (Korovessis et al, 2005;Lee et al, 2011;Li et al, 2012;Watkins et al, 2014). The reason for this is not yet fully understood, but residual IVD tissue seems to alter and/or block the ossification of the spine Tekari et al, 2017), a fact that could explain why BMP-2-coated implants have a rather neutral effect in meta-analyses (Carragee et al, 2011;Simmonds et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

A review of the application of reinforced hydrogels and silk as biomaterials for intervertebral disc repair

Frauchiger¹,

Tekari²,

Wöltje³

et al. 2017

eCM

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The degeneration of the intervertebral disc (IVD) within the spinal column represents a major pain source for many patients. Biological restoration or repair of the IVD using "compressive-force-resistant" and at the same time "cytocompatible" materials would be desirable over current purely mechanical solutions, such as spinal fusion or IVD implants. This review provides an overview of recent research on the repair of the inner (nucleus pulposus = NP) and the outer (annulus fibrous = AF) parts of the IVD tissue. Many studies have addressed NP repair using hydrogel-like materials. However, only a few studies have so far focused on AF repair. As the AF possesses an extremely low self-healing capacity and special attention to shear-force resistance is essential, special repair designs are required. In our review, we stated the challenges in IVD repair and highlighted the use of composite materials such as silk biomaterials and fibrin cross-linked reinforced hydrogels. We elaborated on the origin of silk and its many in tissue engineering. Furthermore, techniques such as electrospinning and 3D printing technologies allow the fabrication of versatile and functionalised 3D scaffolds. We summarised the research that has been conducted in the field of regenerative medicine over the recent years, with a special focus on the potential application and the potential of combining silk and reinforced -and thus mechanically tailored -hydrogels for IVD repair.

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“…10,11 However, the specific capacitance of MC is still relatively low for practical EDLCs. 12,13 Although sophisticated carbon aerogels, 14 carbon nanotubes, 15 and porous carbon prepared by the template method 16 or catalytic activation 17 to penetrate mesoporous carbon have been developed, their capacitance is still not satisfactory due to their low specific surface area. Ideally, the carbon electrode for high performance EDLCs should have both a high surface area and a suitable pore size for electrolyte ions.…”

Section: Introductionmentioning

confidence: 99%

Preparation and Capacitive Performance of Mesoporous Carbon with Short Time CO2 Activation

et al. 2014

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The porous carbon material was prepared from sawdust impregnated with a 0.1 M FeCl 3 aqueous solution with CO 2 activation at 800°C. Pores were found to develop with increasing activation time. The BET surface area, average pore diameter and volume of the mesopores also became greater with increasing activation time. The ratio of the mesopore to total pore volume in the activated carbon was more than 90% after 5 min of activation. Precise control of the pore size distribution is possible by finely tuning the activation time. The porous carbonized material was examined for use in electric double layer capacitor (EDLC) electrodes. The charge and discharge characteristics of EDLC electrodes using these carbonized materials were studied. Cyclic voltammetry and rate performance indicated good correlation between the pore structure of the carbonaceous materials and the magnitude of the electrolyte. These relationships were in good agreement with the Nyquist plot obtained by measuring the impedance. These results were also in accordance with pore structure analysis obtained using the nitrogen adsorption method. It is suggested that the Nyquist diagram characterizes the pore structure of porous carbon from the viewpoint of ion transfer.

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The relation between zoledronic acid infusion and interbody fusion in patients undergoing transforaminal lumbar interbody fusion surgery

Abstract: There was no association between ZOL treatment and nonunion of the lumbar spinal bone. Thus, undergoing lumbar interbody fusion surgery is not a valid reason to suspend or avoid treatment with ZOL.

Cited by 40 publications

References 23 publications

Timing of the initiation of bisphosphonates after surgery for fracture healing: a systematic review and meta-analysis of randomized controlled trials

Timing of the initiation of bisphosphonates after surgery for fracture healing: a systematic review and meta-analysis of randomized controlled trials

A review of the application of reinforced hydrogels and silk as biomaterials for intervertebral disc repair

Preparation and Capacitive Performance of Mesoporous Carbon with Short Time CO2 Activation

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