Objective
To evaluate the association between serum vitamin D (vitD) level and SYNTAX
(synergy between percutaneous coronary intervention with taxus and cardiac
surgery) score (SS).
Methods
The medical records of consecutive patients, who underwent coronary artery
bypass graft surgery, were retrospectively reviewed. The study group
consisted of 158 patients. Biochemical, clinical, and echocardiographic
parameters and SS were evaluated in all patients. The patients were divided
into 2 groups according to SS (≥23= high, <23= low).
Results
The high SYNTAX score (HSS) group was older and had higher body mass index,
C-reactive protein (CRP), low-density lipoprotein, and fasting plasma
glucose level than the low SYNTAX score (LSS) group. The HSS group had lower
high-density lipoprotein and vitD level than the LSS group. The HSS group
had a higher prevalence of diabetes mellitus (DM), hypertension (HT),
hyperlipidemia (HL), and current smoking patients than the LSS group. On
univariate analysis, age, HT, DM, HL, smoking, CRP, and serum vitD level
were associated with HSS. On multivariate analysis, HT, DM, and HL were
independent predictors of HSS (odds ratio [OR]: 2.137, 95% confidence
interval [CI]: 1.468-2.935,
P
<0.001; OR: 3.559, 95% CI:
2.763-5.927,
P
<0.001; OR: 2.631, 95% CI: 1.529-3.438,
P
<0.001; respectively).
Conclusion
In our study, we have found out that HT, DM, and HL were independent
predictors of HSS. Serum vitD level was not found to be an independent
predictor of HSS.