The relation between selenium, zinc and copper concentration and the trace element dependent antioxidative status

Rükgauer, M.; Neugebauer, Rainer J.; Plecko, Thomas

doi:10.1016/s0946-672x(01)80046-8

Cited by 53 publications

(24 citation statements)

References 13 publications

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“…Rijkgauger et al analyzed trace elements and MDA concentrations in healthy persons. and compared Cu levels and MDA concentrations, and found no correlations between them [15]. There are, moreover, no corresponding data in HD patients in relation to correlation between Cu and MDA.…”

Section: Discussionmentioning

confidence: 87%

Effects of hemodialysis period on levels of blood trace elements and oxidative stress

et al. 2010

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Section: Discussionmentioning

confidence: 87%

Effects of hemodialysis period on levels of blood trace elements and oxidative stress

et al. 2010

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“…Although there may be health risks from tea consumption, this study indicated that teas still contain many trace elements, such as Zn, Se, and Co, that are essential for maintaining and improving human health. The zinc and selenium contained in superoxide dismutase (SOD) act as antioxidants, reducing oxidative damage to cellular DNAs, while enhancing the function of the immune system (Rükaguer et al 2001). According to Azin et al (1998), Zn and Se are effective in preventing breast cancer and esophageal cancer.…”

Section: Resultsmentioning

confidence: 99%

Element Composition of Tea Leaves and Tea Infusions and Its Impact on Health

Shen

Chen

2008

Bull Environ Contam Toxicol

121

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Tea infusion is the most frequently consumed beverage worldwide next to water, with about 20 billion cups consumed daily. In Taiwan, daily consumption averages 2.5 cups of tea infusion per person. Many studies have concluded that tea has numerous beneficial effects on health. However, some undesirable trace elements, such as arsenic, chromium, cadmium, lead, etc., are a concern. This study has three aims: (1) to measure the concentrations of arsenic and heavy metal elements, such as chromium, cadmium, and lead, as well as the essential trace elements contained in dried tea leaves of the common brands in Taiwan; (2) to determine the percentage released and concentration of each of these elements after infusion of these tea leaves with boiling water; (3) to assess the carcinogenic risk from daily tea consumption, to provide reference values for the general public. This study showed the total content of arsenic and heavy metals in green tea, oolong tea, and black tea produced in Taiwan was 0.11, 5.61, and 10.11 microg/g, respectively, indicating that the level of arsenic and heavy metal contamination of tea leaves was lower in Taiwan than other regions of the world. The hazard index (HI) of daily tea drinking of green tea, oolong tea, and black tea was low and within the bounds of safety (<1). Tea is an indispensable part of everyday life for many people in Taiwan, studies should continue to ensure that public health is maintained.

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“…Selenium, which is an essential trace metal and inactivates sulfhydryl groups in certain enzymes and is also a component of glutathione peroxidase (Rukgauer et al 2001). This ubiquitous enzyme located in both cytosol and mitochondrial matrix uses glutathione to reduce organic hydroperoxides, thereby, prevents oxidative damage to various cell organelles.…”

Section: Discussionmentioning

confidence: 99%

Time dependent study to evaluate the efficacy of zinc on hepatic marker enzymes and elemental profile in serum and liver of protein deficient rats

2005

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This study was designed to determine the time dependent protective effects of zinc sulfate on the serum and liver marker enzymes along with elemental profile in protein deficient Sprague Dawley (S.D.) female rats. Zinc sulfate in the dose of 227 mg/l in drinking water was administered to normal control as well as protein deficient rats for a total duration of 8 weeks. The effects of different treatments were studied on enzymes like alkaline phosphatase (ALP), aspartate aminotransferases (AST) and alanine aminotransferases (ALT) in rat serum at different time intervals of 1, 2, 4 and 8 weeks and in the rat liver at the end of study. The status of different essential elements in liver was also studied. The serum ALP activity got significantly depressed when estimated at the intervals of 4 and 8 weeks. Activity of serum ALT was significantly increased after 4 weeks interval in protein deficient rats and the increasing trend continued upto 8 weeks of protein deficiency. On the other hand, activity of AST showed a significant increase just after 2 weeks and activity continued to be increased up to 8 weeks. Moreover activities of all the hepato marker enzymes showed a significant increase in liver of protein deficient rats. Interestingly, supplementation of Zn to protein deficient rats helped in regulating the altered activities of ALP, AST and ALT both in serum and liver. However, zinc treatment alone to normal rats did not indicate any significant change in the activities of all the enzymes in liver as well serum except at the interval of 2 weeks where a marginal increase in the activity of AST was seen. It has also been observed that concentrations of zinc, copper, iron and selenium were found to be decreased significantly in protein deficient animals. However, the levels of these elements came back to within normal limits when zinc was administered to protein deficient rats.

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The relation between selenium, zinc and copper concentration and the trace element dependent antioxidative status

Cited by 53 publications

References 13 publications

Effects of hemodialysis period on levels of blood trace elements and oxidative stress

Effects of hemodialysis period on levels of blood trace elements and oxidative stress

Element Composition of Tea Leaves and Tea Infusions and Its Impact on Health

Time dependent study to evaluate the efficacy of zinc on hepatic marker enzymes and elemental profile in serum and liver of protein deficient rats

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