The relation between platelet-to-lymphocyte ratio and Pulmonary Embolism Severity Index in acute pulmonary embolism

Kundi, Harun; Balun, Ahmet; Çiçekçioğlu, Hülya; Çetın, Mustafa; Kızıltunç, Emrullah; Çetin, Mustafa; Mansuroglu, Candan; Örnek, Ender

doi:10.1016/j.hrtlng.2015.04.007

Cited by 43 publications

(34 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Ulutas Med J 2017;3(1): [13][14][15][16][17][18][19] and specificity values of CTPA increased, making it the first-line imaging method (17)(18)(19)(20). CTPA allows not only detection of presence of thrombus but also calculation of the pulmonary arterial computed tomographic obstruction index ratio (PACTOIR), which indicates the degree of thrombus and yields objective results (1).…”

Section: Discussionmentioning

confidence: 99%

“…Platelet activation and chemokine secretion also plays an important role in APE. There are studies which provide information as to PLR and aggregation and inflammatory process in thromboembolic events (13,25). Kundi et al (13) demonstrated that PLR and a simplified version of pulmonary embolism severity index (sPESI) and mortality were correlated in APE.…”

Section: Discussionmentioning

confidence: 99%

“…A significant difference was found between the NLR values of both groups. In the study on PLR levels, Kundi et al (13) reported that a cut-off value of 149 for PLR was significant for high sPESI scores and that mortality rates were statistically higher beyond this value. In our study, average PLR was found to be 271±157 in the high PACTOIR group versus 171±86 in low PACTOIR group.…”

Section: Discussionmentioning

confidence: 99%

“…Ulutas Med J 2017;3(1): [13][14][15][16][17][18][19] then calculated as: (n×d)/40×100 [n=score of embolus multiplied by the number of dependent segments; d=degree of obstruction].…”

Section: Methodsmentioning

confidence: 99%

“…There are studies which demonstrate that NLR, and APE-related mortality development are correlated and that Platelet-Lymphocyte Ratio (PLR), another inflammatory marker, and the clinical severity classification of APE are also correlated (12,13).…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Correlation Between Clot Load Burden with Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios in Patients with Acute Pulmonary Embolism

Çildağ¹,

Çildağ²

2017

Ulutas Med J

View full text Add to dashboard Cite

Background: The correlation between neutrophil-lymphocyte ratio (NLR) and acute pulmonary embolism (APE) related mortality, platelet-lymphocyte ratio (PLR) and clinical severity classification of APE were demostrated. Also clot load burden one of the prognostic criteria of pulmonary embolism.Method: The pulmonary arterial computed tomographic obstruction index ratio (PACTOIR) was calculated in 62 patients diagnosed with APE, retrospectively. Patients were divided into two groups according to their PACTOIR values. NLR and PLR were calculated from the blood samples collected on the day of diagnosis.Results: Mean PACTOIR, NLR and PLR of all patients with APE were calculated as 23.58%, 4.4 and 186.5, respectively. A positive correlation was observed between PACTOIR and NLR and PLR (p<0.001). A statistically significant difference was found between the NLR and PLR levels of low and high PACTOIR groups (p<0.05).Conclusion: A statistically significant correlation was found between PACTOIR and NLR and PLR in patients with APE. According to the findings of our study, NLR and PLR ratios may give an idea about the thrombus load in patients with clinically suspected APE.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Ulutas Med J 2017;3(1): [13][14][15][16][17][18][19] then calculated as: (n×d)/40×100 [n=score of embolus multiplied by the number of dependent segments; d=degree of obstruction].…”

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Correlation Between Clot Load Burden with Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios in Patients with Acute Pulmonary Embolism

Çildağ¹,

Çildağ²

2017

Ulutas Med J

View full text Add to dashboard Cite

show abstract

Clinical characteristics, risk factor analysis and peripheral blood cell changes for early warning of multidrug‐resistant bacteria (MDR) infection in elderly patients

Nie,

Zeng

2024

Immunity Inflam & Disease

View full text Add to dashboard Cite

ObjectiveTo explore peripheral blood indicators that may serve as early indicators for multidrug‐resistant bacteria (MDR) infections in this demographic, with the goal of providing reference suggestions for the clinical prevention of MDR infections in elderly inpatients.MethodsClinical data of patients were divided into the MDR‐infected group (n = 488) and the MDR‐uninfected group (n = 233) according to the results of drug sensitivity experiments, risk factors for MDR infection, and peripheral blood indicators related to MDR infections were analyzed using univariate and multivariate logistic regression in conjunction with the construction of a Chi‐squared automatic interaction detector (CHAID) decision tree model, considering statistical significance at p < .05.ResultsOf 721 patients, 488 multidrug‐resistant strains were identified. Among them, with Staphylococcus spp. the most prevalent in 148 strains. The most frequent detection of MDR occurred in puncture fluid samples (167 cases). Univariate and multivariate regression analyses revealed that prolonged hospitalization, use of antibiotics preadmission, duration of antibiotics, invasive procedures or recent surgery, and coexisting lung disease were independent risk factors for contracting MDR. Subsequent analysis comparing the aforementioned influences with peripheral blood cells revealed associations between the number of antibiotic treatment days and increased neutrophil‐to‐lymphocyte ratio (NLR), platelet count‐to‐lymphocyte ratio (PLR), neutrophils, decreased lymphocytes, and increased eosinophils; preadmission antibiotic use correlated with increased PLR, NLR, neutrophils, and decreased lymphocytes; and invasive manipulation or surgery correlated with increased PLR and NLR.ConclusionsElevated NLR, PLR, neutrophils, lowered lymphocytes, and eosinophils may serve as early indicators of MDR infections in elderly hospitalized patients.

show abstract

Diagnostic validity of hematologic parameters in evaluation of massive pulmonary embolism

Ateş

Kundi

et al. 2016

J Clin Lab Anal

Self Cite

View full text Add to dashboard Cite

show abstract

The relation between platelet-to-lymphocyte ratio and Pulmonary Embolism Severity Index in acute pulmonary embolism

Cited by 43 publications

References 22 publications

Correlation Between Clot Load Burden with Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios in Patients with Acute Pulmonary Embolism

Correlation Between Clot Load Burden with Neutrophil-Lymphocyte and Platelet-Lymphocyte Ratios in Patients with Acute Pulmonary Embolism

Clinical characteristics, risk factor analysis and peripheral blood cell changes for early warning of multidrug‐resistant bacteria (MDR) infection in elderly patients

Diagnostic validity of hematologic parameters in evaluation of massive pulmonary embolism

Contact Info

Product

Resources

About