The relation between motivational concordance and response expectancy

Kelley, John M.

doi:10.1016/j.jpsychores.2008.05.001

Cited by 2 publications

(2 citation statements)

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“…While the neurobiological processes of placebo and nocebo responses have begun to be identified [7], quantifiable neurobiological measures are impractical in large clinical trials. However, treatment expectancies (which are more easily measured) may be a primary driver of placebo and nocebo responses [55][56][57]. Response expectancy theory posits that what people experience is strongly shaped by what they expect to experience [2,58].…”

Section: Does the Instrument Predict Placebo And Nocebo Responses?mentioning

confidence: 99%

Development of the Stanford Expectations of Treatment Scale (SETS): A tool for measuring patient outcome expectancy in clinical trials

et al. 2012

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Section: Does the Instrument Predict Placebo And Nocebo Responses?mentioning

confidence: 99%

Development of the Stanford Expectations of Treatment Scale (SETS): A tool for measuring patient outcome expectancy in clinical trials

et al. 2012

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“…hope). In addition, cognitive appraisals have behavioural consequences [45] and it is these behavioural consequences that have an effect on long-term placebo outcome. The effect of motivationalaffective mechanisms on physiology is the same as those identified in psychoneuroimmunology: the satisfaction of higher level goals in particular has affective and immunological consequences.…”

Section: The Theory That Placebo Mechanisms Are Context-specificmentioning

confidence: 99%

Motivation and placebos: do different mechanisms occur in different contexts?

Hyland

2011

Phil. Trans. R. Soc. B

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This paper challenges the common assumption that the mechanisms underlying short-term placebo paradigms (where there is no motivation for health improvement) and long-term placebo paradigms (where patients value improvement in their health) are the same. Three types of motivational theory are reviewed: (i) classical placebo motivation theory that the placebo response results from the desire for therapeutic improvement; (ii) goal activation model that expectancy-driven placebo responses are enhanced when the placebo response satisfies an activated goal; and (iii) motivational concordance model that the placebo response is the consequence of concordance between the placebo ritual and significant intrinsic motives. It is suggested that current data are consistent with the following theory: response expectancy, conditioning and goal activation are responsible for short-term placebo effects but long-term therapeutic change is achieved through the effects of goal satisfaction and affect on the inflammatory response system and hypothalamic -pituitaryadrenal axis. Empirical predictions of this new theory are outlined, including ways in which placebo effects can be combined with other psychologically mediated effects on short-term and long-term psychological and physiological state.

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The relation between motivational concordance and response expectancy

Cited by 2 publications

References 6 publications

Development of the Stanford Expectations of Treatment Scale (SETS): A tool for measuring patient outcome expectancy in clinical trials

Development of the Stanford Expectations of Treatment Scale (SETS): A tool for measuring patient outcome expectancy in clinical trials

Motivation and placebos: do different mechanisms occur in different contexts?

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