The Relation Between Loss of a Family Member and Oral Lichen Planus in Iraqi Population

Abstract

background Oral lichen planus is common oral mucosal lesions with several predisposing factors, but with poorly identified etiology. Stressor factors could be one of etiological causes for eruption of the lesion and/or a predisposing factor for its appearance, aggravating the excited lesion. The aim of this study to evaluate certain circumstances that were passed on Iraqi population that may be related to elevated OLP incidence in Iraq. Material and method One hundred twenty-nine clinical charts for oral lichen planus patients were taken from oral pathology department college of dentistry university of Baghdad from a period 2009 to 2017. Results Fifty-eight patients only involved in the inclusion criteria of this study, the patients classified according to history associated eruption of the lesion into loss of one family member, trouble associated and both loss and trouble group .The mean age 48.37±12.2 ,the lesion most common in female than male 1.7:1,bilateral involvement of the lesion and mostly on buccal mucosa with slight higher of the red lesions over the reticular making elevated symptoms associated with the lesion mostly the burning sensation .About 65%of the patients presented within one to six months of eruption of the lesion. Conclusion The stressor events affect the age and the symptoms associated with eruption of oral lichen planus lesion.

Salivary Interleukin-6 Level in Iraqi Patients with Oral Lichen Planus receiving Platelet-Rich Plasma Injections

“…Before and after treatment, the salivary levels of interleukin-6 were assessed in each patient and the levels found to be higher after PRP treatment; Table (2). in relation to the location of the lesion, its size, the phenotype of the lesion, colour change, and signs or symptoms that the patient was experiencing the levels of IL-6 were compared.…”

“…Oral lichen planus (OLP) is a chronic inflammatory lesion of the oral mucosae, its related to aberrant cellular immunity (1), Genetics, psychological state and infectious agents may act as causes and /or triggers (2). It's found that all the possible causes of OLP lesion production have the capacity to modulate the oxidative status (3), and this is approved by the decreased salivary anti-oxidant capacity in OLP patients (4).…”

Comparasion between Salivary biomarkers (macrophage inflammatory protein-1α and 1β ) in patients with oral lichen planus and patients with oral lichen planus and skin lesions

“…''An oral mucosal illness with an unknown cause called oral lichen planus (OLP) is a chronic inflammatory T-cell-mediated condition'' [3]''. ''Infectious agents, psychological conditions, and genetic factors can all operate as causes or triggers'' [4]''. ''It has been discovered that all potential causes of OLP lesion generation have the ability to alter the oxidative status'' [5],''and this is supported by the fact that OLP patients have lower salivary anti-oxidant capability'' [6]''.…”