The relation between exercise- induced myocardial ischemia and high-sensitive C-reactive protein and neopterin levels

Başar, Nurcan; Yaşar, Ayşe Saatçı; Erden, Gönül; Cagli, Kumral; Şen, Nihat; Metin, Fatma; Yeşilay, Asuman Biçer; Gürel, Ozgür Malçok; Özcan, Fırat; Yildirimkaya, Metin; Gölbaşı, Zehra; Erbay, Ali Rıza

doi:10.5152/akd.2010.158

Cited by 3 publications

(2 citation statements)

References 27 publications

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“…A study in Turkey reported that after exercise stress test there was a significant increase of 0.5 mg/L of post-exercise stress test hs-CRP level over the baseline in subjects with obstructive coronary lesions, while there was no increase in subjects without obstructive coronary lesions. (31) The study in Turtu concluded exercise induced a significant increment in inflammatory markers i.e., white blood count, hs-CRP, IL-6, IL-10 and MCP-1 concentrations. The long-distance sculling intensity variables such as the average rating of perceived exertion, HR and blood lactate were correlated with changes in IL-8, IL-1α and IL-1β levels.…”

Section: Discussionmentioning

confidence: 99%

Baseline and Post-exercise High-Sensitivity C-Reactive Protein Levels in Endurance Cyclists: The Indonesian North Coast and Tour de Borobudur 2017 Study

et al. 2019

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BACKGROUND: Inflammation plays an important role in the atherosclerotic process. High-sensitivity C-reactive-protein (hs-CRP) is commonly used as inflammatory biomarker. It is well known that regular physical activity lowers hs-CRP levels, while prolonged exercise induces hs-CRP elevations. However, the relationship of training and exercise characteristics with hs-CRP levels remains not well elucidated. We evaluated baseline and post-exercise hs-CRP levels and its association with training and exercise characteristics.METHODS: Eighty-eight male endurance cyclists were involved. Demographic data, health condition and training characteristics were collected. Baseline and postexercise blood-samples were collected to determine hsCRP concentrations. A hs-CRP cut-off point of 3 mg/L was used. Blood-cell count and biochemical parameters were measured at baseline. Heart rate (HR) was measured during exercise.RESULTS: Cyclists performed 7.3 hours (interquartilerange (IQR) = 5.4-7.5) of endurance exercise at intensity of 81.8 % (IQR = 74.9-85.8). Cyclists with baseline hsCRP ≥ 3 mg/L reported higher body mass, body mass index (BMI), waist-circumference and total-cholesterol. An increase in hs-CRP was following endurance exercise. Cyclists with any elevation of hs-CRP reported a higher BMI, HR during exercise and exercise intensity. Binary logistic regression analysis showed BMI (OR = 1.24, 95% CI = 1.04-1.48) and cycling distance (OR = 0.22, 95% CI = 0.06-0.76) were associated with post-exercise hs-CRP elevations.CONCLUSION: Body mass, BMI, waist-circumference, total- and HDL-cholesterol are associated with baseline hsCRP, whereas BMI and cycling distance were associated with hs-CRP elevations. These findings suggest that anthropometry parameters and lipid levels attributed to baseline hs-CRP, while anthropometry parameters and cycling intensity attributed to post-exercise hs-CRP elevations.KEYWORDS: C-reactive-protein, exercise, endurancecycling, inflammation, acute-phase-response

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Section: Discussionmentioning

confidence: 99%

Baseline and Post-exercise High-Sensitivity C-Reactive Protein Levels in Endurance Cyclists: The Indonesian North Coast and Tour de Borobudur 2017 Study

et al. 2019

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“…The conventional criterion for the detection of myocardial ischemia is the development of ST‐segment depression or elevation during the test; however, the diagnostic value of this criterion is limited because of its relatively low sensitivity. To improve the identification of myocardial ischemia with this modality, various parameters, such as P‐wave duration, hs‐CRP elevation, ST elevation in aVR derivation, abnormal heart rate recovery, troponin, and NT‐pro‐BNP‐levels with ST‐segment depression or copeptin level have recently been suggested …”

Section: Introductionmentioning

confidence: 99%

Combination of change in hematological parameters with exercise stress test to predict coronary artery disease

Korkmaz

Yıldız

Duyuler

et al. 2017

Clinical Laboratory Analysis

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Objective: Treadmill exercise stress testing for identifying patients with a higher likelihood of coronary artery disease (CAD) before elective coronary angiography is recommended in the current guidelines. In this study, we aimed to evaluate the changes in the hematological parameters before and after exercise stress test in relation with the presence of CAD. Methods:A total of 113 patients with chest pain who underwent treadmill exercise testing and coronary angiography were included in this study. Conclusions: Neutrophil to lymphocyte ratio is an important inflammatory marker that can contribute to treadmill ECG testing in predicting CAD.

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Evaluation of Subclinical Atherosclerosis in Chronic Sinusitis patients

Cakici

Sarıkaya

Çetın

et al. 2015

Arch Turk Soc Cardiol

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The relation between exercise- induced myocardial ischemia and high-sensitive C-reactive protein and neopterin levels

Cited by 3 publications

References 27 publications

Baseline and Post-exercise High-Sensitivity C-Reactive Protein Levels in Endurance Cyclists: The Indonesian North Coast and Tour de Borobudur 2017 Study

Baseline and Post-exercise High-Sensitivity C-Reactive Protein Levels in Endurance Cyclists: The Indonesian North Coast and Tour de Borobudur 2017 Study

Combination of change in hematological parameters with exercise stress test to predict coronary artery disease

Evaluation of Subclinical Atherosclerosis in Chronic Sinusitis patients

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