The regulatory role of miRNA and lncRNA on autophagy in diabetic nephropathy

Yu, Siming; Li, Yue; Lu, Xinxin; Han, Zehui; Li, Chunsheng; Yuan, Xingxing; Guo, Dandan

doi:10.1016/j.cellsig.2024.111144

Cited by 3 publications

(1 citation statement)

References 99 publications

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“…Conversely, inhibiting autophagy or knocking down ATF6 reversed the decrease in anaphylactic reaction caused by ORMDL3 overexpression ( Li et al, 2021 ). Autophagy has also been linked to epithelial mesenchymal transition (EMT) and epigenetic changes in the fields of oncology, lung diseases, and diabetes ( Ranieri et al, 2021 ; Zeng et al, 2021 ; Gundamaraju et al, 2022 ; Yu et al, 2024 ). Both EMT and epigenetic changes play roles in the pathogenesis of CRS ( Li et al, 2022 ; Wang et al, 2023 ).…”

Section: Concluding Remarks and Future Perspectivesmentioning

confidence: 99%

Autophagy in chronic rhinosinusitis with or without nasal polyps

Pei,

Ding,

Jiao

et al. 2024

Front. Cell Dev. Biol.

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Basic research on chronic rhinosinusitis (CRS) has advanced significantly in the past two decades, yet a comprehensive understanding of its pathogenic mechanisms remains elusive. Concurrently, there is a growing interest among scientists in exploring the involvement of autophagy in various human diseases, including tumors and inflammatory conditions. While the role of autophagy in asthma has been extensively studied in airway inflammatory diseases, its significance in CRS with or without nasal polyps (NPs), a condition closely linked to asthma pathophysiology, has also garnered attention, albeit with conflicting findings across studies. This review delves into the role of autophagy in CRS, suggesting that modulating autophagy to regulate inflammatory responses could potentially serve as a novel therapeutic target.

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Section: Concluding Remarks and Future Perspectivesmentioning

confidence: 99%

Autophagy in chronic rhinosinusitis with or without nasal polyps

Pei,

Ding,

Jiao

et al. 2024

Front. Cell Dev. Biol.

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A systematic review of epigenetic interplay in kidney diseases: Crosstalk between long noncoding RNAs and methylation, acetylation of chromatin and histone

Tan,

Jia,

et al. 2024

Biomedicine & Pharmacotherapy

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Exploring Mitochondrial Interactions with Pulsed Electromagnetic Fields: An Insightful Inquiry into Strategies for Addressing Neuroinflammation and Oxidative Stress in Diabetic Neuropathy

Chianese,

Bonora,

Sambataro

et al. 2024

IJMS

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Pulsed electromagnetic fields (PEMFs) are recognized for their potential in regenerative medicine, offering a non-invasive avenue for tissue rejuvenation. While prior research has mainly focused on their effects on bone and dermo-epidermal tissues, the impact of PEMFs on nervous tissue, particularly in the context of neuropathy associated with the diabetic foot, remains relatively unexplored. Addressing this gap, our preliminary in vitro study investigates the effects of complex magnetic fields (CMFs) on glial-like cells derived from mesenchymal cell differentiation, serving as a model for neuropathy of the diabetic foot. Through assessments of cellular proliferation, hemocompatibility, mutagenicity, and mitochondrial membrane potential, we have established the safety profile of the system. Furthermore, the analysis of microRNAs (miRNAs) suggests that CMFs may exert beneficial effects on cell cycle regulation, as evidenced by the upregulation of the miRNAs within the 121, 127, and 142 families, which are known to be associated with mitochondrial function and cell cycle control. This exploration holds promise for potential applications in mitigating neuropathic complications in diabetic foot conditions.

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The regulatory role of miRNA and lncRNA on autophagy in diabetic nephropathy

Cited by 3 publications

References 99 publications

Autophagy in chronic rhinosinusitis with or without nasal polyps

Autophagy in chronic rhinosinusitis with or without nasal polyps

A systematic review of epigenetic interplay in kidney diseases: Crosstalk between long noncoding RNAs and methylation, acetylation of chromatin and histone

Exploring Mitochondrial Interactions with Pulsed Electromagnetic Fields: An Insightful Inquiry into Strategies for Addressing Neuroinflammation and Oxidative Stress in Diabetic Neuropathy

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