The Rectal Gland of the Shark: The Road to Understanding the Mechanism and Regulation of Transepithelial Chloride Transport
Patricio Silva,
David H. Evans
Abstract:Pictured, described, speculated upon, for close to 400 years, the function of the rectal gland of elasmobranchs remained unknown. In the late 1950s Burger discovered that the rectal gland of Squalus acanthias secreted an almost pure solution of sodium chloride, isosmotic with blood, that could be stimulated by volume expansion of the fish. Twenty five years later, Stoff discovered that the secretion of the gland was mediated by adenyl cyclase. Studies since then have shown that Vasoactive intestinal peptide (V… Show more
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