The recognition of scurvy with especial reference to the early x-ray changes

Park, Edwards A.; Guild, Harriet G.; Jackson, Dudley P.; Bond, Marian

doi:10.1136/adc.10.58.265

Cited by 61 publications

(10 citation statements)

References 1 publication

(1 reference statement)

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“…Park, Guild, Jackson, & Bond, 1935), although Barlow noted clustered porosity under a subdural hematoma in a scorbutic child (Barlow, 1883, p. 182). This is probably because this abnormal porosity is not radiographically visible and is not observable in living individuals.…”

Section: The “Ortner Criteria”: Paleopathological Inference Using Knomentioning

confidence: 99%

Macroscopic features of scurvy in human skeletal remains: A literature synthesis and diagnostic guide

Snoddy

Buckley

Elliott

et al. 2018

American J Phys Anthropol

101

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The past two decades have seen a proliferation in bioarchaeological literature on the identification of scurvy, a disease caused by chronic vitamin C deficiency, in ancient human remains. This condition is one of the few nutritional deficiencies that can result in diagnostic osseous lesions. Scurvy is associated with low dietary diversity and its identification in human skeletal remains can provide important contextual information on subsistence strategy, resource allocation, and human‐environmental interactions in past populations. A large and robust methodological body of work on the paleopathology of scurvy exists. However, the diagnostic criteria for this disease employed by bioarchaeologists have not always been uniform. Here we draw from previous research on the skeletal manifestations of scurvy in adult and juvenile human skeletal remains and propose a weighted diagnostic system for its identification that takes into account the pathophysiology of the disease, soft tissue anatomy, and clinical research. Using a sample of individuals from the prehistoric Atacama Desert in Northern Chile, we also provide a practical example of how diagnostic value might be assigned to skeletal lesions of the disease that have not been previously described in the literature.

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Section: The “Ortner Criteria”: Paleopathological Inference Using Knomentioning

confidence: 99%

Macroscopic features of scurvy in human skeletal remains: A literature synthesis and diagnostic guide

Snoddy

Buckley

Elliott

et al. 2018

American J Phys Anthropol

101

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“…Possibly the complete ring indicates a fracture not through the metaphysis but through the growth plate, with continuing chondroMetabolic Diseases. In the case of scurvy the increased incidence of the disease in summer [38] is difficult to explain on any other basis than as a direct effect of growth rate on metaphyseal fragility.…”

Section: Failure In Shearmentioning

confidence: 96%

“…The classical example of failure in this zone is scurvy, where the lag in osteogenesis perpetuates an otherwise transient weakness [32,38,40].…”

Section: Evidence From Other Clinical States Involving Junctional Zonmentioning

confidence: 99%

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Effect of growth rate on the strength of the growth plate-shaft junction

Alexander

1976

Skeletal Radiol.

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Abstract. This paper investigates the relation between metaphyseal zone fragility and growth rate. It is concluded that there are two sites of weakness, the hypertrophic zone of the plate and the metaphysis. From a study of the age incidence of traumatic plate fractures compared with that of shaft fractures, it is deduced that fragility of both zones is a non-linear function of growth rate. It is concluded that this correlation explains the occurrence and age incidence of a range of diseases in which plate fractures occur in shear, and of central Schmorl's node which is a metaphyseal fracture in compression. The mechanism of plate fragility appears to be an increase in thickness of the hypertrophic zone from any cause, including rickets as well as increased growth. No evidence is found to implicate endocrine imbalance as a necessary factor in the normal transient fragility of the growth spurt.Key words: Growth plate --Bone growth --Plate fracture -Metaphysis Battered child --Epiphysidysis --Scheuermann's disease. rate, and to determine if possible which of the three mechanisms is the most likely.

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“…6 Indefinite history. 4 Reduced by vomiting..7. Proprietary preparations not containing ascorbic acid.…”

Section: Diagnosismentioning

confidence: 99%