The reappearance of Victoria lineage influenza B virus in Brazil, antigenic and molecular analysis

Motta, Fernando Couto; Siqueira, Marilda Mendonça; Lugon, Ana Kelly; Straliotto, Selir Maria; Fernandes, Sandra Bianchini; Krawczuk, M.M.

doi:10.1016/j.jcv.2006.03.008

Cited by 13 publications

(12 citation statements)

References 16 publications

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“…Our literature review confirms the re-emergence of B/Victoria lineage in Brazil during the years 2000-2002. These data are in line with that of Motta et al 48 which shows the re-emergence of the Victoria-lineage viruses in the Northern hemisphere and in the South and South East regions of Brazil where previously the B/Yamagata lineage was the predominating circulating lineage and the vaccine recommended lineage. Other studies confirm that the B/Yamagata was the major circulating lineage until the 1980s, when B/Victoria lineage viruses appeared; since then, drift variants of both influenza B lineages have been co-circulating worldwide.…”

Section: Discussionsupporting

confidence: 92%

“…Other studies confirm that the B/Yamagata was the major circulating lineage until the 1980s, when B/Victoria lineage viruses appeared; since then, drift variants of both influenza B lineages have been co-circulating worldwide. 49,50 As influenza B viruses can co-circulate during an epidemic allowing the re-emergence of old lineages due to re-assortment between the different strains, 4,48 there is a need to improve influenza laboratory-based surveillance in Brazil. Importantly these data also highlight the unpredictability of influenza B circulation, making it difficult to consistently predict which B lineage will predominate during a given influenza season.…”

Section: Discussionmentioning

confidence: 99%

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Patterns of influenza B circulation in Brazil and its relevance to seasonal vaccine composition

Barros

Cintra

Rossetto³

et al. 2016

The Brazilian Journal of Infectious Diseases

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Data on the burden of disease and circulation patterns of influenza B lineages for Brazil are limited. This review aims to describe the pattern of influenza B occurrence in Brazil to have a better understanding of its epidemiology and its relevance when considering seasonal influenza vaccine composition. A review of the data including analysis of international and local surveillance data as well as information from online search of databases using Medical Subject Headings terms in conjunction with screening of abstracts from scientific events was performed. Based on international epidemiologic surveillance data, moderate levels of influenza B disease (19%; 2006-2014) were observed. Of these nine years, it was possible to compare data from three years (2007, 2008 and 2013) which have information on the circulating influenza B lineage. Co-circulation of influenza B lineages was observed in all these three influenza seasons, of which, during one season, a high degree of mismatch between the vaccine lineage and the predominant circulating lineage (91.4% [2013]) was observed. Local surveillance data reveal a distinct and dynamic distribution of respiratory viruses over the years. Data from published literature and abstracts show that influenza B is a significant cause of disease with an unpredictable circulation pattern and showing trends indicating reemergence of the B/Victoria lineage. The abstracts report notable levels of co-circulation of both influenza B lineages (2000-2013). Mismatch between the Southern hemisphere vaccine and the most prevalent circulating viruses in Brazil were observed in five influenza seasons. The evidence on co-circulation of two influenza B lineages and mismatched seasons in Brazil indicates the benefit of quadrivalent influenza vaccines in conferring broader seasonal influenza protection. Additionally, improving influenza surveillance platforms in Brazil is important for monitoring disease trends and the impact of introducing seasonal influenza vaccination.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 99%

Patterns of influenza B circulation in Brazil and its relevance to seasonal vaccine composition

Barros

Cintra

Rossetto³

et al. 2016

The Brazilian Journal of Infectious Diseases

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“…Influenza viruses were also common in Sao Paulo, with a circulation pattern of viruses types A and B, which is consistent with what was reported by the National Surveillance for this region of the country in the study period [Motta et al, 2006]. Overall influenza activity was considered low according to the WHO Influenza Network Surveillance [WHO, 2001[WHO, , 2002[WHO, , 2003.…”

Section: Discussionsupporting

confidence: 84%

Acute respiratory infection and influenza‐like illness viral etiologies in Brazilian adults

Bellei

Carraro

Perosa

et al. 2008

Journal of Medical Virology

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Influenza-like illness (ILI) definitions have been used worldwide for influenza surveillance. These different case definitions can vary with regard to sensitivity and predictive values for laboratory confirmed influenza. The literature has indicated the inclusion of other viruses may be the cause of these variable results. The objective of the study was to evaluate ILI national sentinel criteria and viral etiologies in adults diagnosed with acute respiratory infection (ARI) and/or ILI from 2001 to 2003 in Sao Paulo, Brazil. Clinical and laboratory evaluations were observed from 420 adults and collected on a daily basis from outpatient care units at University Hospital. The ILI definition included: fever plus at least one respiratory symptom (cough and/or sore throat) and one constitutional symptom (headache, malaise, myalgia, sweat or chills, or fatigue). DFA and RT-PCR for influenza, parainfluenza, respiratory syncytial virus, adenovirus, enterovirus, coronavirus, rhinovirus, and metapneumovirus were performed on nasal washes and 61.8% resulted positive. The respiratory viruses detected most often were influenza and rhinovirus. ILI was reported for 240/420 patients (57.1%), with influenza and rhinovirus etiologies accounting for 30.9% and 19.6%, respectively. Rhinovirus peak activity was concurrent with the influenza season. These findings highlight the implications of other viruses in ILI etiology and suggest that during the influenza season, this clinical overlap must be considered in the diagnosis and clinical management of patients.

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“…Influenza-virus types found during the study period correlated well with those of the influenza isolates from official surveillance in this region of the country, with a prevalence of influenza A in 2001 and 2003, and influenza B in 2002 [7]. Reappearance of Influenza B Victoria-lineage was replaced by the Yamagata-lineage during 2002, which diverged from the recommended seasonal vaccine, and was more prevalent than influenza type A [9].…”

Section: Discussionmentioning

confidence: 68%

Patterns of influenza infections among different risk groups in Brazil

et al. 2007

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Influenza virus infections are associated with high morbidity and mortality. Influenza activity varies worldwide, and regional detection is influenced by geographic conditions, demographic and patient-risk factors. We assessed influenza activity and patterns of seasonality during three consecutive years (2001-2003) in three risk groups in São Paulo city. Four-hundred-twelve outpatients with acute respiratory infection were subjected to epidemiological, clinical and laboratory investigations; these included community population (N=140), health-care workers (N=203), and renal-transplanted patients (N=69). Nasal wash samples were tested by direct fluorescent assay for influenza, parainfluenza, adenovirus, and respiratory syncytial virus. Overall Influenza positivity was 21%, and a progressive decline was observed in all groups over time. Influenza A and B co-circulated at the same time in 2001 and 2002, but not in 2003. Low influenza-vaccination rates (19%) were reported by health-care workers. Unexpected low levels of etiological agents were detected in renal-transplanted patients, and infected cases were less symptomatic than immunocompetent patients. Based on this study, we conclude that health-care worker-immunization programs should be implemented and the clinical patterns of infected influenza patients should be used as a guide for better case-definition criteria for adequate influenza surveillance, particularly for renal-transplant patients.

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The reappearance of Victoria lineage influenza B virus in Brazil, antigenic and molecular analysis

Cited by 13 publications

References 16 publications

Patterns of influenza B circulation in Brazil and its relevance to seasonal vaccine composition

Patterns of influenza B circulation in Brazil and its relevance to seasonal vaccine composition

Acute respiratory infection and influenza‐like illness viral etiologies in Brazilian adults

Patterns of influenza infections among different risk groups in Brazil

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