The realization of a project aimed at reducing the plasmatic lipid level in a large Italian population improves the mean calcium daily intake: the Brisighella Study

Derosa

Bove

et al. 2009

Mediterr J Nutr Metab

nificant improvement on plasma triglyceride concentration (-13.3%) and systolic (-3.9%) and diastolic blood pressure (-2.6%). No significant difference was observed regarding the standard diet group in comparison to the baseline. On the basis of our data, psyllium could be more strongly indicated for patients that have to reduce a large number of cardiovascular risk factors, while guar gum could be more rapidly efficacious in strengthening the effect of diets aimed at reducing body weight.

Section: Methodsmentioning

confidence: 99%

Psyllium improves dyslipidaemia, hyperglycaemia and hypertension, while guar gum reduces body weight more rapidly in patients affected by metabolic syndrome following an AHA Step 2 diet

Derosa

Bove

et al. 2009

Mediterr J Nutr Metab

“…The study was promoted in 1972 by Professor G. Descovich [21]. Subjects were clinically evaluated at baseline and every 4 years following enrolment when extensive clinical and laboratory data were obtained in addition to the assessment of morbidity and mortality.…”

Section: Methodsmentioning

confidence: 99%

Adipokines and Sexual Hormones Associated with the Components of the Metabolic Syndrome in Pharmacologically Untreated Subjects: Data from the Brisighella Heart Study

International Journal of Endocrinology

Magni

Morè

et al. 2011

We evaluated the association of the sex hormone pattern and the serum level of the main adipokines to metabolic syndrome (MS) and its components in 199 pharmacologically untreated subjects. Men and women included in the age-class subgroups were matched for body mass index, waist circumference, blood pressure, heart rate, fasting plasma glucose, and plasma lipids. Men without MS had significantly lower leptin/adiponectin ratio than men with MS. Women without MS had lower leptin and leptin/adiponectin ratio than women with MS but had significantly higher adiponectin, estrone, and dehydroepiandrosterone levels. In men, the leptin/adiponectin ratio is the main factor associated to MS diagnosis (OR: 3.36, 95% CI 1.40–8.08), while in women adiponectin alone appears to be a protective factor (OR: 0.87, 95% CI 0.79–0.95). In conclusion, in a sample of pharmacologically untreated subjects, leptin/adiponectin ratio seems to be the factor more strongly associated to MS and its components.

“…Dietary compliance was monitored during the study by a dietician who recorded information on the 7-day nutritional diary for each subject individually at each study stage. The seven-day questionnaire used in this study has been previously described [19]. Blood samples were drawn from an antecubital vein after a 12-h overnight fast; serum was separated by centrifugation at 4000 rpm for 20 min and stored at -80°C.…”

Section: Methodsmentioning

confidence: 99%

Plasma lipid effects of corn oil and extra-virgin olive oil in hypercholesterolaemic subjects: a randomised, controlled trial

D’Addato

Fiorito

et al. 2009

Mediterr J Nutr Metab

The aim of our study was to directly compare the metabolic effect of monounsaturated fatty acid rich oils and polyunsaturated fatty acid rich oils on the plasma lipid pattern of moderately hypercholesterolaemic subjects under controlled isocaloric condition. After a 30-day run-in diet, 44 healthy Caucasian subjects with moderate hypercholesterolaemia were randomly assigned to one of four different isocaloric diets, differing only regarding the oil used (corn oil, corn oil supplemented with vitamin E, extra-virgin olive oil or different self-selected oils), for 45 days. At the end of the study, when compared to the baseline value, low-density lipoprotein (LDL)-cholesterolaemia was significantly lower only in patients taking corn oil (-13.9%; 95%CI -5.9 to -20.1; p = 0.02) or corn oil with added vitamin E (-19.1%; 95%CI -6.9 to -24.1; p = 0.03). Differences in plasma high-density lipoprotein (HDL)-cholesterol and triglyceride levels from baseline levels and between the four diets did not reach statistical significance.