The RB gene locates on chromosome 15 at band 15q13 in the Syrian hamster

Satoh, Hitoshi; Ebert, Robert H.; Wiseman, Roger W.; Barrett, J. Carl

doi:10.1159/000133617

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Cited by 3 publications

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“…Tp53 is the third gene and the second tumoi suppressor gene localized in Syrian hamster chromosomes; a human cDNA probe for N-rz/.v (NRAS) and a Syrian hamster cDNA probe homologous to the hitman retinoblastoma gene (RBI) have been mapped to chromosome arms 12q and 15q, respectively (Issa ct al.. 1992: Satoh et al. 1994).…”

Section: Resultsmentioning

confidence: 99%

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Localization of the <i>Tp53</i> gene on Syrian hamster chromosome 9 by fluorescence in situ hybridization

Popescu

Zimonjic²,

Albor³

et al. 1995

Cytogenet Genome Res

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Mutations of the Tp53 tumor suppressor gene have been detected in 50% of all human cancers. The normal Tp53 gene product acts as a negative regulator of cell division or is associated with abnormal growth in certain differentiated cell types. The Tp53 gene was mapped by FISH to Syrian hamster chromosome 9 bands qb2.2→2.3 using a genomic DNA probe with a high degree of sequence identity to the human Tp53 gene.

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Section: Resultsmentioning

confidence: 99%

“…However, only recently have cancer-related genes been localized in Syrian hamster chromosomes (Issa et al. 1992;Satoh et al, 1994 H ybridization, washing, detection, an d digital image acquisition and processing were perform ed as previously described (Zim onjic et al, 1994) …”

mentioning

confidence: 99%