The Rationale for Treating Iron Deficiency Anemia

Crosby, William H.

doi:10.1001/archinte.1984.00350150055016

Cited by 45 publications

(25 citation statements)

References 9 publications

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“…Although more evidence is clearly needed, we recommend that in patients who show symptoms attributable to moderate or severe anemia of inflammation, and do not suffer from overwhelming or difficult to control infection, iron-restricted erythropoiesis can and should be treated, an argument that is not new. 78 In iron-restricted anemias other than absolute iron deficiency, the optimal treatment is still evolving and may be improved by the ongoing development of hepcidin-targeted therapies.…”

Section: Resultsmentioning

confidence: 99%

Detection, evaluation, and management of iron-restricted erythropoiesis

Goodnough

Nemeth

Ganz

2010

Blood

371

349

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Section: Resultsmentioning

confidence: 99%

Detection, evaluation, and management of iron-restricted erythropoiesis

Goodnough

Nemeth

Ganz

2010

Blood

371

349

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“…Th e degree of constipation is directly proportional to the amount of elemental iron ingested, with some formulations reporting an estimated 50% rate of treatment-related constipation. Th is eff ect can be mitigated by switching to a formulation containing a lower amount of elemental iron (22)(23)(24)(25). Finally, the use of magnesium sulfate as a tocolytic to prevent preterm labor or to treat preeclampsia is also associated with signifi cant constipation.…”

Section: Risk Factorsmentioning

confidence: 99%

Pregnancy and Postpartum Bowel Changes: Constipation and Fecal Incontinence

Shin

Toto

Schey

2015

American Journal of Gastroenterology

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Pregnancy and the postpartum period are often associated with many gastrointestinal complaints, including nausea, vomiting, and heartburn; however, the most troublesome complaints in some women are defecatory disorders such as constipation and fecal incontinence, especially postpartum. These disorders are often multifactorial in etiology, and many studies have looked to see what risk factors lead to these complications. This review discusses the current knowledge of pelvic floor and anorectal physiology, especially during pregnancy, and reviews the current literature on causes and treatments of postpartum bowel symptoms of constipation and fecal incontinence.

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“…Both these interventions are heavily dependent on utilising ferrous iron based products. The iron salt ferrous sulphate (FeSO 4 ), first used as an iron supplement in the 19th century, is the most commonly used iron source in current use (Andrews, 1999;Crosby, 1984). Despite the development of several novel iron forms over the past decades ferrous sulphate remains the first choice, mainly due to its low cost (Martnez-Navarrete et al 2002).…”

Section: Introductionmentioning

confidence: 99%