The rationale behind collecting umbilical cord blood

Abstract

Umbilical cord blood (UCB) is an increasingly important and rich source of stem cells. These cells can be used for the treatment of many diseases, including cancers and immune and genetic disorders. For patients for whom no suitable related donor is available, this source of hematopoietic stem cells offers substantial advantages, notably the relative ease of procurement, the absence of risk to the donor, the small likelihood of transmitting clinically important infections, the low risk of severe graft-versus-host disease (GVHD) and the rapid availability of placental blood for transplantation centers. Even though almost 80 diseases are treatable with cord blood stem cells, 97 percent of cord blood is still disposed of after birth and lost for patients in need! To improve availability of stem cells to a broader community, efforts should be undertaken to collect cord blood and expectant parents should be properly informed of their options with regard to cord blood banking. (J Turkish-German Gynecol Assoc 2010; 11: 99-101) Key words: Stem cell, umbilical Abstract ÖzetReview 99

Hematological reference intervals among full-term newborns in Ethiopia: a cross-sectional study

“…The UCB is composed of white blood cells (WBC), red blood cells (RBC), plasma, platelets and is also rich in hematopoietic stem cells, which have immense potential to cure the malignant and genetic disorder. Therefore, establishing of hematological RI among newborns from UCB is very important for neonatologist for the diagnosis RBC disorders (like anemia and polycythemia), hematological malignancy, platelet disorders (like thrombosis and thrombocytopenia), autoimmune disease, certain genetic disorders problems, monitoring of the patients during in a therapeutic regimen and diagnosis of various bacterial infections [5][6][7]. It is widely known that newborn hematological parameters are different from those of infants or adults.…”

Hematological reference intervals among full-term newborns in Ethiopia: a cross-sectional study

“…The minimum vs maximum value of cord WBC, cord RBC, and cord platelet among study participants were (3.6 vs 27) x10 6…”

“…Therefore, establishing of hematological RI among newborns from UCB is very important for neonatologist for the diagnosis RBC disorders (like anemia and polycythemia), hematological malignancy, platelet disorders (like thrombosis and thrombocytopenia), autoimmune disease, certain genetic disorders problems, monitoring of the patients during in a therapeutic regimen and diagnosis of various bacterial infections (5)(6)(7). It is widely known that newborn hematological parameters are different from those of infants or adults.…”

To Established Hematological Reference Intervals Among Full-Term Newborn Babies at University of Gondar Comprehensive Specialized Hospital, Northwest Ethiopia: A Cross-Sectional Study

“…The UCB is composed of white blood cells (WBC), red blood cells (RBC), plasma, platelets and is also rich in hematopoietic stem cells, which have immense potential to cure the malignant and genetic disorder. Therefore, establishing of hematological RI among newborn babies from UCB is very important for neonatologist for the diagnosis RBC disorders (like anemia and polycythemia), hematological malignancy, platelet disorders (like thrombosis and thrombocytopenia), autoimmune disease, certain genetic disorders problems, monitoring of the patients during in a therapeutic regimen and diagnosis of various bacterial infections (5)(6)(7). It is widely known that newborn hematological parameters are different from those of infants or adults.…”