The rational treatment of fractures: Use the evidence with caution

Effect of mechanical strain on the pluripotency of murine embryonic stem cells seeded in a collagen‐I scaffold

“…Bone is a dynamic organ which has the unique ability to truly regenerate; completely restoring bone to its initial biomechanical and biological functions. However, in elderly individuals, patients with fragile bone structure, or following a severe injury, bone regeneration can be delayed or inhibited . Tissue engineering (TE) seeks to develop functional tissue substitutes using a combination of biomaterials, cells, and/or growth factors to promote regeneration/repair .…”

“…However, in elderly individuals, patients with fragile bone structure, or following a severe injury, bone regeneration can be delayed or inhibited. 1,2 Tissue engineering (TE) seeks to develop functional tissue substitutes using a combination of biomaterials, cells, and/or growth factors to promote regeneration/repair. 3,4 Cells are a critical component which provide signals to the surrounding environment to directly or indirectly drive bone regeneration.…”

Indian Journal of Orthopaedics: Journey continues

“…The best evidence can be generated when methodically conducted studies are published in peer-reviewed journals, and are available to orthopedic surgeons far and wide and are a part of metaanalysis to produce validated evidence 1. The journals also have the responsibility to spread knowledge and evidence, generate curiosity among readers to upgrade the knowledge, as well as inculcate the art of critical analysis of the published data and use the evidence rationally 2. The editorial team is the backbone of any journal and association.…”

Art and science of Orthopedics

“…(e) Response of biology (patient's body tissue) to the treatment affected. All these variables will determine whether outcome is going to be predictable or not 1. Summarily, orthopedics (medicine) is science of knowledge and artistic application of knowledge to achieve healing.…”