The ratio between metastatic and examined lymph nodes is an independent prognostic factor for patients with resectable middle and distal bile duct carcinoma

Pancreaticoduodenectomy for distal cholangiocarcinoma: surgical results, prognostic factors, and long-term follow-up

“…Data on patterns of disease recurrence were available only for 12 patients who underwent radical R0 resection: 11 patients recurred with distant metastasis; only one of them developed local recurrence. It has been reported that the frequency of lymph node metastases in distal cholangiocarcinoma ranges from 22 to 58 %, and the absence of lymph node metastases represents a useful predictor of favorable outcome in DBDC [15]. We reported a 54.3 % rate of nodal involvement, and patients with N1 disease showed a markedly worse prognosis if compared with node-negative cases (p=0.02).…”

“…Only few previously published papers analyzed the features of surgically resected DBDC [12][13][14][15][16]. Here, the 13-year experience with 46 DBDC resected at a single institution is reported.…”

Lymph Nodal Involvement as Prognostic Factor in Gallbladder Cancer: Location, Count or Ratio?

“…LNR has been shown to be an important predictor of survival after surgery for pancreatic and bile duct cancer. 5,18 To the best of our knowledge, no study has assessed the association between LNR and survival in patients with gallbladder cancer. Our study suggests that, along with tumor stage and differentiation, LNR is an independent prognostic factor and the single most important lymph nodal variable in patients undergoing curative resection for gallbladder cancer.…”

Number of involved lymph nodes is important in the prediction of prognosis for primary duodenal adenocarcinoma

“…The cutoff value for each group was determined by previous studies. 3,17,18 The seventh edition of AJCC classification for malignant neoplasms of the small intestine was used for staging.…”