The rate of velocity development associates with muscle echo intensity, but not muscle cross-sectional area in older men

Mota, Jacob A.; Giuliani, Hayden K.; Gerstner, Gena R.; Ryan, Eric D.

doi:10.1007/s40520-017-0829-1

Cited by 24 publications

(28 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This finding seems to agree with a variety of studies conducted in older adults who, despite showing worse muscle quality than younger cohorts, typically show EI mean values ≤ 150 A.U. [ 26 – 28 ]. It should be noted, however, that the results of the present study are exclusive to the vastus lateralis, young females, the conditions provided by the study design, and the B-mode ultrasonography device and settings utilized by our laboratory.…”

Section: Discussionsupporting

confidence: 91%

The impact of skeletal muscle disuse on distinct echo intensity bands: A retrospective analysis

et al. 2022

View full text Add to dashboard Cite

Echo intensity (EI) is a novel tool for assessing muscle quality. EI has traditionally been reported as the mean of the pixel histogram, with 0 and 255 arbitrary units (A.U.) representing excellent and poor muscle quality, respectively. Recent work conducted in youth and younger and older adults suggested that analyzing specific EI bands, rather than the mean, may provide unique insights into the effectiveness of exercise and rehabilitation interventions. As our previous work showed deterioration of muscle quality after knee joint immobilization, we sought to investigate whether the increase in EI following disuse was limited to specific EI bands. Thirteen females (age = 21 yrs) underwent two weeks of left knee immobilization and ambulated via crutches. B-mode ultrasonography was utilized to obtain images of the immobilized vastus lateralis. The percentage of the total number of pixels within bands of 0–50, 51–100, 101–150, 151–200, and 201–255 A.U. was examined before and after immobilization. We also sought to determine if further subdividing the histogram into 25 A.U. bands (i.e., 0–25, 26–50, etc.) would be a more sensitive methodological approach. Immobilization resulted in a decrease in the percentage of pixels within the 0–50 A.U. band (-3.11 ± 3.98%), but an increase in the 101–150 A.U. (2.94 ± 2.64%) and 151–200 A.U. (0.93 ± 1.42%) bands. Analyses of variance on the change scores indicated that these differences were large and significant (%EI0-50 vs. %EI101-150: p < .001, d = 1.243); %EI0-50 vs. %EI151-200: p = .043, d = 0.831). The effect size for the %EI51-100 versus %EI101-150 comparison was medium/large (d = 0.762), but not statistically significant (p = .085). Further analysis of the 25 A.U. bands indicated that the percentage of pixels within the 25–50 A.U. band decreased (-2.97 ± 3.64%), whereas the 101–125 (1.62 ± 1.47%) and 126–150 A.U. (1.18 ± 1.07%) bands increased. Comparison of the 50 A.U. and 25 A.U. band methods found that 25 A.U. bands offer little additional insight. Though studies are needed to ascertain the factors that may influence specific bands, changes in EI during muscle disuse are not homogeneous across the pixel histogram. We encourage investigators to think critically about the robustness of data obtained from EI histograms, rather than simply reporting the EImean value, in muscle quality research.

show abstract

Section: Discussionsupporting

confidence: 91%

The impact of skeletal muscle disuse on distinct echo intensity bands: A retrospective analysis

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Measures of skeletal muscle structure obtained using diagnostic ultrasonography have been found to be related to measures of force and physical function (30,33,46,48,(62)(63)(64)(65)(66)(67)(68)(69).…”

Section: Discussionmentioning

confidence: 99%

Rate of Force Development Is Related to Maximal Force and Sit-to-Stand Performance in Men With Stages 3b and 4 Chronic Kidney Disease

Gollie¹,

Harris‐Love²,

Patel³

et al. 2021

Front. Rehabilit. Sci.

View full text Add to dashboard Cite

Introduction: The primary aims of the present study were to assess the relationships of early (0–50 ms) and late (100–200 ms) knee extensor rate of force development (RFD) with maximal voluntary force (MVF) and sit-to-stand (STS) performance in participants with chronic kidney disease (CKD) not requiring dialysis.Methods: Thirteen men with CKD (eGFR = 35.17 ±.5 ml/min per 1.73 m2, age = 70.56 ±.4 years) and 12 non-CKD men (REF) (eGFR = 80.31 ± 4.8 ml/min per 1.73 m2, age = 70.22 ±.9 years) performed maximal voluntary isometric contractions to determine MVF and RFD of the knee extensors. RFD was measured at time intervals 0–50 ms (RFD0−50) and 100–200 ms (RFD100−200). STS was measured as the time to complete five repetitions. Measures of rectus femoris grayscale (RF GSL) and muscle thickness (RF MT) were obtained via ultrasonography in the CKD group only. Standardized mean differences (SMD) were used to examine differences between groups. Bivariate relationships were assessed by Pearson's product moment correlation.Results: Knee extensor MVF adjusted for body weight (CKD=17.14 ±.1 N·kg0.67, REF=21.55 ±.3 N·kg0.67, SMD = 0.79) and STS time (CKD = 15.93 ±.4 s, REF = 12.23 ±.7 s, SMD = 1.03) were lower in the CKD group than the REF group. Absolute RFD100−200 was significantly directly related to adjusted MVF in CKD (r = 0.56, p = 0.049) and REF (r = 0.70, p = 0.012), respectively. STS time was significantly inversely related to absolute (r = −0.75, p = 0.008) and relative RFD0−50 (r = −0.65, p = 0.030) in CKD but not REF (r = 0.08, p = 0.797; r = 0.004, p = 0.991). Significant inverse relationships between RF GSL adjusted for adipose tissue thickness and absolute RFD100−200 (r =−0.59, p = 0.042) in CKD were observed.Conclusion: The results of the current study highlight the declines in strength and physical function that occur in older men with CKD stages 3b and 4 not requiring dialysis. Moreover, early RFD was associated with STS time in CKD while late RFD was associated MVF in both CKD and REF.Clinical Trial Registration: ClinicalTrials.gov, identifier: NCT03160326 and NCT02277236.

show abstract

“…EI is thought to be a non-invasive surrogate measure of muscle quality, as increased EI is associated with infiltration of intramuscular fat, collagen, and fibrous and connective tissue (10,(12)(13)(14). Although numerous investigations have demonstrated that muscle EI is related to functional ability, strength, and power (3,6,(13)(14)(15)(16)(17)(18)(19), studies using EI as a proxy of muscle quality after resistance training have generated inconsistent results (4,6,13,(20)(21)(22)(23), leading researchers to question the true physiological interpretation of muscle EI (24).…”

Section: Introductionmentioning

confidence: 99%

Influence of muscle depth and thickness on ultrasound echo intensity of the vastus lateralis

et al. 2020

View full text Add to dashboard Cite

Background Ultrasonography is used to evaluate muscle quality (i.e. echo intensity [EI]), but an attenuation of ultrasound waves occurs in deeper tissues, potentially affecting these measures. Purpose To determine whether muscle thickness (MT) affects EI and if EI varies between the superficial and deep portions of the muscle. Materials and Methods MT, EI, subcutaneous adipose tissue thickness (SAT), tissue depth (DISDEEP), and EI of the overall (EIFULL) as well as deep (EIDEEP) and superficial (EISUPF) portions of the vastus lateralis (VL) were assessed in 33 resistance-trained males using ultrasonography. The difference (EIDIFF) between EISUPF and EIDEEP was calculated. Mean differences between EIFULL, EISUPF, and EIDEEP were analyzed using a repeated-measures analysis of variance (ANOVA). Relationships between measures of muscle depth/ thickness and EI were examined using Pearson’s r. Results EISUPF was greater than EIDEEP ( P < 0.001) and EIFULL ( P < 0.001). MT was negatively correlated with EIFULL ( P < 0.001) and positively correlated with EIDIFF ( P < 0.001). SAT was not correlated with any EI measure, but DISDEEP was positively correlated with EIDIFF ( P < 0.001). Conclusion EI of the VL is heterogeneous, as the deeper portion produces lower values than the superficial portion. Thicker muscles present lower EI but have greater discrepancies in EI between the superficial and deep portions. Although SAT was not correlated with EI, DISDEEP was related to EIDIFF, demonstrating that the combination of MT and SAT should be considered when evaluating muscle quality. Future research is necessary to determine if changes in EI following resistance training are driven by increases in MT.

show abstract

The rate of velocity development associates with muscle echo intensity, but not muscle cross-sectional area in older men

Cited by 24 publications

References 15 publications

The impact of skeletal muscle disuse on distinct echo intensity bands: A retrospective analysis

The impact of skeletal muscle disuse on distinct echo intensity bands: A retrospective analysis

Rate of Force Development Is Related to Maximal Force and Sit-to-Stand Performance in Men With Stages 3b and 4 Chronic Kidney Disease

Influence of muscle depth and thickness on ultrasound echo intensity of the vastus lateralis

Contact Info

Product

Resources

About