The rapid effect of pulsed dye laser on demodex density of facial skin

Ertaş, Ragıp; Yaman, Ozan; Akkuş, Muhammed Reşat; Özlü, Emin; Avcı, Atıl; Ulaş, Yılmaz; Özyurt, Kemal; Atasoy, Mustafa

doi:10.1080/14764172.2018.1481509

Cited by 16 publications

(20 citation statements)

References 19 publications

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“…Nd:YAG laser also acts on papulopustules but is more effective in ETR than in PPR [177]. These actions on the papulopustules may result from a potential acaricidal effect as a result of increasing skin temperature [178] and, for the Nd:YAG laser, by destruction of the follicular unit [177]. One study suggested that these therapies may therefore be used not only in ETR but also in demodicosis [178], although these findings need to be confirmed.…”

Section: Current Treatments For Vascular Symptoms Of Rosacea: Acaricimentioning

confidence: 99%

“…These actions on the papulopustules may result from a potential acaricidal effect as a result of increasing skin temperature [178] and, for the Nd:YAG laser, by destruction of the follicular unit [177]. One study suggested that these therapies may therefore be used not only in ETR but also in demodicosis [178], although these findings need to be confirmed. Coagulation necrosis of the Demodex mites has been observed after IPL treatment; nevertheless, the mites recolonized the skin 1 month after the second treatment [179].…”

Section: Current Treatments For Vascular Symptoms Of Rosacea: Acaricimentioning

confidence: 99%

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The Pathogenic Role of Demodex Mites in Rosacea: A Potential Therapeutic Target Already in Erythematotelangiectatic Rosacea?

Forton¹

2020

Dermatol Ther (Heidelb)

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Rosacea is an inflammatory continuum, with all characteristics being already present from the onset of the disease, even if not clinically visible. Demodex proliferation also appears to be a continuum process in rosacea, and high Demodex density is beginning to be accepted as an important trigger of the inflammatory cascade and as a marker of rosacea: moreover, papulopustules of rosacea can be treated using acaricides. Immunological studies are providing new hypotheses according to which Demodex may induce tolerogenic dendritic cells and collaborate with VEGF to induce T cell exhaustion favoring its own proliferation. This proliferation may not be clinically visible initially. The interactions among VEGF, Demodex, and immunity need to be explored, and the nosology of rosacea definitions adapted accordingly. The effectiveness of treating any patient who only has visible vascular symptoms with an acaricidal cream needs to be confirmed in prospective controlled clinical trials with long-term follow-up, but it is already important to detect patients with pityriasis folliculorum among those with only vascular symptoms of rosacea in order to treat at least these patients with an acaricidal cream. DIGITAL FEATURES This article is published with digital features to facilitate understanding of the article. You can access the digital features on the article's associated Figshare page. To view digital features for this article go to

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Section: Current Treatments For Vascular Symptoms Of Rosacea: Acaricimentioning

confidence: 99%

Section: Current Treatments For Vascular Symptoms Of Rosacea: Acaricimentioning

confidence: 99%

The Pathogenic Role of Demodex Mites in Rosacea: A Potential Therapeutic Target Already in Erythematotelangiectatic Rosacea?

Forton¹

2020

Dermatol Ther (Heidelb)

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“…6 There are only a few reports about the effect of PDL or IPL therapy on Demodex mites. 7,8 To our knowledge, no report exists to date, which evaluates the effect of neodymium: yttrium aluminum garnet (Nd:YAG) laser irradiation on Dd. Herein, we present a patient who had a simultaneous decrease in Dd after one session of 1064 nm Nd:YAG laser application for facial telangiectasias of ETR.…”

mentioning

confidence: 99%

“…The authors speculated two possible mechanisms of IPL application to induce coagulation necrosis of Demodex mites that the mite may contain some chromophores which make it more sensitive than the hair follicule to the energy delivered by IPL device or the spherical structures of the mite may not be able to transfer the energy to the open-ended cylindrical hair follicles. More recently, pulsed dye laser (PDL) application wasreported to significantly reduce Dd in facial skin after one session 7.…”

mentioning

confidence: 99%

The decrease of demodex density after Nd: YAG laser application for facial telengiactasias: A case report

Yalıcı-Armağan

Elçin

2020

Dermatologic Therapy

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“…Nowadays, a wide range of treatments for rosacea is available: topical metronidazole, oral metronidazole, topical ivermectin, oral tetracyclines, oral azithromycin (1), oral isotretinoin, systemic steroids, photodynamic therapy, or pulsed dye laser (2). However, in pregnant patients, as several medications can cause significant fetal harm, the treatment alternatives are limited.…”

Section: Discussionmentioning

confidence: 99%

Use of permethrin in the treatment of rosacea fulminans during pregnancy: One case report

Garayar-Cantero

Solovera

García

et al. 2020

Dermatologic Therapy

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Rosacea fulminans (RF) is a rare dermatological condition which occurs exclusively in women and it is characterized by a sudden onset of painful papules, pustules, cysts, and nodules on the face. A 28‐year‐old woman was referred to our clinic due to a painful facial eruption within the 13th week of her second pregnancy. After physical examination, the diagnosis of RF during pregnancy was established. Several treatments were used: mupirocin ointment, topical zinc oxide, topical erythromycin, oral erythromycin, metronidazole gel, oral metronidazole, oral amoxiciline, and oral prednisone. Finally, the patient was started on 5% permethrin cream with complete clearing of the lesions. Nowadays, a wide range of treatments for rosacea is available: topical metronidazole, oral metronidazole, topical ivermectin, oral tetracyclines, oral isotretinoin, systemic steroids, photodynamic therapy, or pulsed dye laser. However, in pregnant patients, the treatment alternatives are limited. We consider that 5% permethrin cream could be an effective, cheap, and safe treatment not only in regular patients with rosacea but also in pregnant women, representing an important alternative in the context of pregnancy when therapeutic options are limited. To our knowledge, this is the first case of rosacea treated with 5% permethrin cream in monotherapy during pregnancy.

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The rapid effect of pulsed dye laser on demodex density of facial skin

Cited by 16 publications

References 19 publications

The Pathogenic Role of Demodex Mites in Rosacea: A Potential Therapeutic Target Already in Erythematotelangiectatic Rosacea?

The Pathogenic Role of Demodex Mites in Rosacea: A Potential Therapeutic Target Already in Erythematotelangiectatic Rosacea?

The decrease of demodex density after Nd: YAG laser application for facial telengiactasias: A case report

Use of permethrin in the treatment of rosacea fulminans during pregnancy: One case report

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