The Raf‐like kinase Raf36 negatively regulates plant resistance against the oomycete pathogen <i>Phytophthora parasitica</i> by targeting MKK2

Li, Jinfang; Deng, Fengyan; Wang, Hongmei; Qiang, Xiaoyu; Meng, Yuling; Shan, Weixing

doi:10.1111/mpp.13176

Cited by 7 publications

(6 citation statements)

References 56 publications

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“…For instance, MPK3a and MPK3b genes had the clear functions in response to UV-B, cold, and freezing [56] , [57] , [58] . M2K2a and M2K2b genes were with oomycete pathogen resistance [59] and cold acclimation [60] , M2K9 could give cellular response to hypoxia [61] . M3K3A and M3K5G could resist to both bacterial and fungal pathogens [62] , and adapt to the QTP wild environment.…”

Section: Discussionmentioning

confidence: 99%

Insights into the plateau adaptation of Salvia castanea by comparative genomic and WGCNA analyses

Cao

Wang

et al. 2022

Journal of Advanced Research

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Section: Discussionmentioning

confidence: 99%

Insights into the plateau adaptation of Salvia castanea by comparative genomic and WGCNA analyses

Cao

Wang

et al. 2022

Journal of Advanced Research

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“…AtRaf36, a Raf-like protein kinase in Arabidopsis, was found to negatively regulate plant resistance to pathogen Phytophthora parasitica by targeting the downstream MKK2 kinase. Loss of Raf36 enhances the resistance to P. parasitica and the resistance mediated by Raf36 might be counteracted by mkk2 mutation [ 87 ]. Tobacco NPK1 not only plays a role in the cytokinesis process, but also participates in the response to tobacco mosaic virus (TMV) resistance.…”

Section: Role Of Map3k In Plant Responses To Biotic Stressesmentioning

confidence: 99%

MAPKKKs in Plants: Multidimensional Regulators of Plant Growth and Stress Responses

Xie

Liu

Gai

2023

IJMS

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Mitogen-activated protein kinase kinase kinase (MAPKKK, MAP3K) is located upstream of the mitogen-activated protein kinase (MAPK) cascade pathway and is responsible for receiving and transmitting external signals to the downstream MAPKKs. Although a large number of MAP3K genes play important roles in plant growth and development, and response to abiotic and biotic stresses, only a few members’ functions and cascade signaling pathways have been clarified, and the downstream MAPKKs and MAPKs of most MAP3Ks are still unknown. As more and more signaling pathways are discovered, the function and regulatory mechanism of MAP3K genes will become clearer. In this paper, the MAP3K genes in plants were classified and the members and basic characteristics of each subfamily of MAP3K were briefly described. Moreover, the roles of plant MAP3Ks in regulating plant growth and development and stress (abiotic and biotic) responses are described in detail. In addition, the roles of MAP3Ks involved in plant hormones signal transduction pathway were briefly introduced, and the future research focus was prospected.

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Section: Uncanonical Regulation Of Mapk Cascades By Mapkkksmentioning

confidence: 99%

“…In addition, Arabidopsis Raf36 (a Raf-like MAPKKK), which possesses kinase activity and belongs to the Raf-like kinase group [ 79 ], was recently found to negatively regulate plant disease resistance by targeting MKK2 (a MAPKK) [ 58 ]. Raf36 interacts with MKK2 in plants, and phosphorylates MKK2 in vitro [ 58 , 59 ] ( Table 2 ). The genetic data indicating that MKK2 positively regulates plant disease resistance and that MKK2 knockout compromises raf36 -mediated disease resistance supports the Raf36-MKK2 signaling cascade.…”

Section: Uncanonical Regulation Of Mapk Cascades By Mapkkksmentioning

confidence: 99%

Regulatory Mechanisms of Mitogen-Activated Protein Kinase Cascades in Plants: More than Sequential Phosphorylation

Gao

Wang

et al. 2022

IJMS

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Mitogen-activated protein kinase (MAPK) cascades play crucial roles in almost all biological processes in plants. They transduce extracellular cues into cells, typically through linear and sequential phosphorylation and activation of members of the signaling cascades. However, accumulating data suggest various regulatory mechanisms of plant MAPK cascades in addition to the traditional phosphorylation pathway, in concert with their large numbers and coordinated roles in plant responses to complex ectocytic signals. Here, we highlight recent studies that describe the uncanonical mechanism of regulation of MAPK cascades, regarding the activation of each tier of the signaling cascades. More particularly, we discuss the unusual role for MAPK kinase kinases (MAPKKKs) in the regulation of MAPK cascades, as accumulating data suggest the non-MAPKKK function of many MAPKKKs. In addition, future work on the biochemical activation of MAPK members that needs attention will be discussed.

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The Raf‐like kinase Raf36 negatively regulates plant resistance against the oomycete pathogen Phytophthora parasitica by targeting MKK2

Abstract: This is an open access article under the terms of the Creat ive Commo ns Attri butio n-NonCo mmerc ial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

Cited by 7 publications

References 56 publications

Insights into the plateau adaptation of Salvia castanea by comparative genomic and WGCNA analyses

Insights into the plateau adaptation of Salvia castanea by comparative genomic and WGCNA analyses

MAPKKKs in Plants: Multidimensional Regulators of Plant Growth and Stress Responses

Regulatory Mechanisms of Mitogen-Activated Protein Kinase Cascades in Plants: More than Sequential Phosphorylation

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