The radiological and histological investigation of the dental follicle of asymptomatic impacted mandibular third molars

Abstract

Objectives The indication for removal of asymptomatic fully impacted third molars is still controversial. In this study, radiological and histological investigation of the dental follicle of asymptomatic impacted mandibular third molars was performed, aiming to provide a reference for clinical prophylactic extraction of these teeth. Methods Patients with impacted mandibular third molars were included and the maximum width of the dental follicle around the crown was measured in horizontal, sagittal and coronal sections by cone beam computed tomography. The dental follicles were stained with haematoxylin-eosin, analysed by a pathologist and classified as normal, inflammatory or cystic. A Chi-squared test was used to analyse the association of the incidence of inflammation and cysts with the clinical variables of the impacted mandibular third molars. Results Thirty-seven samples were normal dental follicles; 52 samples showed inflammatory infiltration with an incidence of 57.14%; 2 samples with a maximum dental follicle width of 2–3 mm were diagnosed as odontogenic cysts, and the incidence was 2.20%. There was no significant difference in the incidence of inflammatory and cystic dental follicles between males and females, or between different age groups (P > 0.05). With an increase of the maximum width of the dental follicle, there was a rise in the incidence and degree of infiltration of chronic nonspecific inflammation. Conclusion Asymptomatic impacted mandibular third molars tend to be extracted, especially for teeth with a 2–3 mm maximum width of the dental follicle on radiological examination.

Estudio histopatológicdel tejido pericoronario en terceros molares, incluidos aparentemente sanos

“…Se evidenció que la mayor parte de la muestra analizada, es decir, un 84,2% (32) no presentaba infiltrado inflamatorio, restando un total de 15,8% (6) que refleja en el examen histopatológico la presencia de infiltrado inflamatorio en el tejido pericoronario caracterizado (FIGURA 6).…”

“…Calderón-Peña JA et al 14 refieren que el QD de tipo inflamatorio constituyo el 60% de los casos examinados, encontrando un infiltrado inflamatorio crónico o mixto; en este sentido sugiere la extracción profiláctica de los terceros molares con el argumento que ellos son generadores de patologías, añadiendo que esta situación persiste como un tema controversial. Li K et al 32 , examinaron folículos dentales normales de terceros molares incluidos, reportaron infiltración inflamatoria con una incidencia del 57,14%; con un aumento del ancho máximo del folículo dental, hubo un aumento en la incidencia y el grado de infiltración de la inflamación crónica inespecífica; señalando que los terceros molares mandibulares impactados asintomáticos tienden a ser extraídos, especialmente en dientes con un ancho máximo de 2-3 mm del folículo dental en el examen radiológico.…”

Role of αENaC in root resorption of adjacent teeth due to entirely impacted mandibular third molars

“…However, few have explored what happened there. Although the dental follicle of asymptomatic impacted mandibular third molars has been investigated from the radiological and histological view [ 25 ], few explored what happened in ERR of M2Ms due to EIM3Ms.…”

Inter-Rater Reliability Regarding the Radiolucencies Associated with the Second Molar Adjacent an Impacted Third Mandibular Molar

“…11,12 A relationship between the width of the peri-coronal space and the presence of an epithelial lining associated with an impacted tooth has been previously reported. 13,14,15,16 This is not a vast body of literature exploring the domain of inter-rater reliability of dental specialists regarding pathologies and radiolucencies associated with second molars adjacent to an impacted third molar. According to our study, the only radiolucency that rater 1 observed was external resorption.…”