The radical cation of trimethylphosphine oxide

Gas‐phase reactivity of the OP(OCH3)2+ phosphonium ion with aliphatic esters in a quadrupole ion trap. Spontaneous elimination of ketenes

“…Formation of protonated phosphonates has been observed in the quadrupole ion trap (QIT) spectrometer under electron ionization (EI) 3. The study of the gas‐phase reactivity of long‐lived radical cation of trimethylphosphine oxide has demonstrated that this ion is a Brønsted acid and likely to have a distonic structure with a carbon radical center 4. The kinetic method has been applied to order the relative affinities of a group of substituted pyridines towards PCl 2 + and to seek relationships with the affinities towards other chlorinated cations 5.…”

Ketalization of phosphonium ions by 1,4-dioxane: Selective detection of the chemical warfare agent simulant DMMP in mixtures using ion/molecule reactions

“…Kenttämaa found that phosphonium ions CH 3 P(O)OCH 3 ϩ (93 Th) react exclusively with cis-1,2-cyclohexanediol to form CH 3 P(OH) 2 OCH 3 ϩ (111 Th) by water abstraction [14]. Related studies [15][16][17] demonstrated that the long-lived radical cations of small organophosphates and trimethylphosphine oxide isomerize spontaneously to distonic ions which were characterized using collision-induced dissociation (CID). The reactions of dimethyl methylphosphonate (DMMP) with a variety of anions such as amide, hydrogen sulfide, methoxide, and fluoride have been examined by Lum and Grabowski [18].…”

Replacement of C−O by P−O in Cyclic Acetals and Ketals

“…As an alternative, tethered lipid membranes [3±6] offer attractive possibilities in this context as indicated by the detection and modulation of the channel activity of the small antibiotic peptide gramicidin. [7] Here we probe the function of a well-characterized poreforming, transmembrane receptor protein by the measurement in situ of both the binding of ligands by surface plasmon resonance (SPR) and subsequent changes of the channel activity by impedance spectroscopy (IS). [8,9] The receptor protein OmpF was reconstituted into a fluid lipid bilayer coupled to a gold surface through the sulfur groups of so-called thiolipids [4] present in the bilayer at a defined molar ratio (Figure 1).…”