“…In particular, 9,10-dione derivatives have piqued the interest of medicinal chemists because of their remarkable pharmacological properties, including anti-tumour [ 3 , 4 ], anti-inflammatory [ 5 ], antimalarial [ 6 ], antioxidants, antibacterial [ 7 , 8 ], antiifungal [ 9 ], anti-leukemic [ 10 ], anti-HIV [ 11 ], and anti-tumour activities [ 12 ]. A range of human cancer cell lines, including A2780, HeLa, H7420, Ketr3, and SW 1990, were shown to be cytotoxic by previously described anthraquinone derivatives, such as racemic trimeric quinone and polycyclic quinones, with an IC 50 of 6.2–9.3 μM [ 13 ]. Semisynthetic anthraquinones, including E−1, AE-1, FLE, and FLAE, demonstrate strong antiproliferative effects against HT-29, PC-3, and HeLa cells, although they showed only moderate antioxidant activities [ 14 ].…”