The R2R3-MYB transcription factor MtMYB134 orchestrates flavonol biosynthesis in Medicago truncatula

Naik, Jogindra; Rajput, Ruchika; Pucker, Boas; Stracke, Ralf; Pandey, Ashutosh

doi:10.1007/s11103-021-01135-x

Cited by 42 publications

(48 citation statements)

References 75 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These characteristics may allow alfalfa to adapt to diverse environments. In different geographic alfalfa groups (corresponding to the top 1% tail of Tajima's D values), we found several phenology-related genes (Figure 3C), including Msa0206730 (MsKNOX1, MsG0280008879 in Zhongmu No.1 genome), Msa0876740 (MsMADS20-1, MsG0680030394), Msa0876740 (MsMADS20-2, MsG0680030395) and Msa0868930 (MsMYB, MsG0680030409) which have been shown to be associated with plant growth, development, and flowering (Nishii et al, 2017;Hu et al, 2021;Naik et al, 2021;Pelayo et al, 2021).…”

Section: Selection Footprints Of Alfalfa Breedingmentioning

confidence: 99%

A global alfalfa diversity panel reveals genomic selection signatures in Chinese varieties and genomic associations with root development

Chen

Long

et al. 2021

JIPB

View full text Add to dashboard Cite

Alfalfa (Medicago sativa L.) is an important forage crop worldwide. However, little is known about the effects of breeding status and different geographical populations on alfalfa improvement. Here, we sequenced 220 alfalfa core germplasms and determined that Chinese alfalfa cultivars form an independent group, as evidenced by comparisons of F ST values between different subgroups, suggesting that geographical origin plays an important role in group differentiation.

show abstract

Section: Selection Footprints Of Alfalfa Breedingmentioning

confidence: 99%

A global alfalfa diversity panel reveals genomic selection signatures in Chinese varieties and genomic associations with root development

Chen

Long

et al. 2021

JIPB

View full text Add to dashboard Cite

show abstract

“…In M. truncatula, R2R3-MYB134 positive regulator flavanol biosynthesis [117]. Ectopic overexpression of LjaMYB12 from Lonicera japonica enhances the flavonol accumulation in the model plant Arabidopsis [7].…”

Section: The Flavonol Biosynthetic Pathway Is Regulated By Myb Transcription Factormentioning

confidence: 99%

“…2021, 22, x 10 of 23 assay indicated that VvMYBF1 controls the expression of FLS1 and many other promoters of Arabidopsis and grapevine. In M. truncatula, R2R3-MYB134 positive regulator flavanol biosynthesis [117]. Ectopic overexpression of LjaMYB12 from Lonicera japonica enhances the flavonol accumulation in the model plant Arabidopsis [7].…”

Section: The Flavonol Biosynthetic Pathway Is Regulated By Myb Transcription Factormentioning

confidence: 99%

Recent Advanced Metabolic and Genetic Engineering of Phenylpropanoid Biosynthetic Pathways

Anwar

Chen

Xiao

et al. 2021

IJMS

View full text Add to dashboard Cite

The MYB transcription factors (TFs) are evolving as critical role in the regulation of the phenylpropanoid and tanshinones biosynthetic pathway. MYB TFs relate to a very important gene family, which are involved in the regulation of primary and secondary metabolisms, terpenoids, bioactive compounds, plant defense against various stresses and cell morphology. R2R3 MYB TFs contained a conserved N-terminal domain, but the domain at C-terminal sorts them different regarding their structures and functions. MYB TFs suppressors generally possess particular repressive motifs, such as pdLNLD/ELxiG/S and TLLLFR, which contribute to their suppression role through a diversity of complex regulatory mechanisms. A novel flower specific “NF/YWSV/MEDF/LW” conserved motif has a great potential to understand the mechanisms of flower development. In the current review, we summarize recent advanced progress of MYB TFs on transcription regulation, posttranscriptional, microRNA, conserved motif and propose directions to future prospective research. We further suggest there should be more focus on the investigation for the role of MYB TFs in microalgae, which has great potential for heterologous protein expression system for future perspectives.

show abstract

“…The loss model proposes that R2R3-MYBs diverged from 3R-MYBs through loss of the R1 repeat [ 13 – 15 ], while the gain model proposes that the 3R-MYBs evolved from the R2R3-MYB through duplication of a repeat [ 10 , 16 ]. R2R3-MYBs are involved in the regulation of numerous processes including the regulation of developmental processes, response to environmental stresses, and specialized metabolism [ 17 – 19 ]. WEREWOLF/MYB66 is a negative regulator of the root hair formation that determines the pattern of root hairs on the root epidermis of Arabidopsis thaliana [ 17 ].…”

Section: Introductionmentioning

confidence: 99%

Automatic identification and annotation of MYB gene family members in plants

Pucker¹

2022

BMC Genomics

Self Cite

View full text Add to dashboard Cite

Background MYBs are among the largest transcription factor families in plants. Consequently, members of this family are involved in a plethora of processes including development and specialized metabolism. The MYB families of many plant species were investigated in the last two decades since the first investigation looked at Arabidopsis thaliana. This body of knowledge and characterized sequences provide the basis for the identification, classification, and functional annotation of candidate sequences in new genome and transcriptome assemblies. Results A pipeline for the automatic identification and functional annotation of MYBs in a given sequence data set was implemented in Python. MYB candidates are identified, screened for the presence of a MYB domain and other motifs, and finally placed in a phylogenetic context with well characterized sequences. In addition to technical benchmarking based on existing annotation, the transcriptome assembly of Croton tiglium and the annotated genome sequence of Castanea crenata were screened for MYBs. Results of both analyses are presented in this study to illustrate the potential of this application. The analysis of one species takes only a few minutes depending on the number of predicted sequences and the size of the MYB gene family. This pipeline, the required bait sequences, and reference sequences for a classification are freely available on github: https://github.com/bpucker/MYB_annotator. Conclusions This automatic annotation of the MYB gene family in novel assemblies makes genome-wide investigations consistent and paves the way for comparative studies in the future. Candidate genes for in-depth analyses are presented based on their orthology to previously characterized sequences which allows the functional annotation of the newly identified MYBs with high confidence. The identification of orthologs can also be harnessed to detect duplication and deletion events.

show abstract

The R2R3-MYB transcription factor MtMYB134 orchestrates flavonol biosynthesis in Medicago truncatula

Cited by 42 publications

References 75 publications

A global alfalfa diversity panel reveals genomic selection signatures in Chinese varieties and genomic associations with root development

A global alfalfa diversity panel reveals genomic selection signatures in Chinese varieties and genomic associations with root development

Recent Advanced Metabolic and Genetic Engineering of Phenylpropanoid Biosynthetic Pathways

Automatic identification and annotation of MYB gene family members in plants

Contact Info

Product

Resources

About