Our investigation was to study the effect of protein levels 25% and 30% within each level protein that four levels of Digestarom ® P.E.P. (0.00, 0.01, 0.02 and 0.03%) on growth performance, feed utilization and economical evaluation of red tilapia fingerlings. Red tilapia fingerlings were fed on eight experimental diets composed of two protein levels a 25 % and 30% crude protein within each protein levels supplemented with Digestarom ® P.E.P. at four levels (0.00, 0.01, 0.02 and 0.03%).The results indicated that protein levels 30% and Digestarom ® at 0.02% had positive effect on the final weight, weight gain, specific growth rate, feed conversion ratio and feed efficiency ratio. The interactions of Digestarom® and protein levels have a significantly higher in growth performance, feed utilization, survival rate and economical evaluation.It could be concluded that the best Digestrom ® levels was 0.02% Digestrom ® in each protein levels 25 and 30 % in terms of growth performance, feed utilization, survival rate and economic evaluation.