In this paper, we study a new flexible three-parameter exponential distribution called the extended odd Weibull exponential distribution, which can have constant, decreasing, increasing, bathtub, upside-down bathtub and reversed-J shaped hazard rates, and right-skewed, left-skewed, symmetrical, and reversed-J shaped densities. Some mathematical properties of the proposed distribution are derived. The model parameters are estimated via eight frequentist estimation methods called, the maximum likelihood estimators, least squares and weighted least-squares estimators, maximum product of spacing estimators, Cramér-von Mises estimators, percentiles estimators, and Anderson-Darling and right-tail Anderson-Darling estimators. Extensive simulations are conducted to compare the performance of these estimation methods for small and large samples. Four practical data sets from the fields of medicine, engineering, and reliability are analyzed, proving the usefulness and flexibility of the proposed distribution.