We are concerned with the problem of detecting with high probability whether a wave function has collapsed or not, in the following framework: A quantum system with a d-dimensional Hilbert space is initially in state ψ; with probability 0 < p < 1, the state collapses relative to the orthonormal basis b1, . . . , b d . That is, the final state ψ is random; it is ψ with probability 1 − p and b k (up to a phase) with p times Born's probability | b k |ψ | 2 . Now an experiment on the system in state ψ is desired that provides information about whether or not a collapse has occurred. Elsewhere [2], we identify and discuss the optimal experiment in case that ψ is either known or random with a known probability distribution. Here we present results about the case that no a priori information about ψ is available, while we regard p and b1, . . . , b d as known.For certain values of p, we show that the set of ψs for which any experiment E is more reliable than blind guessing is at most half the unit sphere; thus, in this regime, any experiment is of questionable use, if any at all. Remarkably, however, there are other values of p and experiments E such that the set of ψs for which E is more reliable than blind guessing has measure greater than half the sphere, though with a conjectured maximum of 64% of the sphere.Key words: collapse of the wave function; limitations to knowledge; absolute uncertainty; empirically undecidable; quantum measurements; foundations of quantum mechanics; Ghirardi-Rimini-Weber (GRW) theory; random wave function.