The quantification with FDG as seen by a physician

Comparison of methods for evaluating radiolabelled Annexin A5 uptake in pre-clinical PET oncological studies

“…The physician's view of the operational difficulties and practical problems associated with different strategies for collecting and analysing PET data in the clinic has recently been vivaciously and provocatively discussed by Galli et al [40]. Admittedly, the use of optimized static imaging protocols and analyses using SUVs has had a tremendous impact on facilitating the clinical use of PET.…”

¹⁸F-ФДГ и другие меченые производные глюкозы для использования в радионуклидной диагностике онкологических заболеваний (обзор)

“…Ïîýòîìó â áîëüøèí-ñòâå ÏÝÒ öåíòðîâ ïðèìåíÿþò ðàçëè÷íûå âàðèàíòû ïîëó-êîëè÷åñòâåííîé îöåíêè, âêëþ÷àþùåé âû÷èñëåíèå èí-äåêñà íàêîïëåíèÿ ÐÔÏ â âèäå îòíîøåíèÿ ìåaeäó íàêîï-ëåííîé êîíöåíòðàöèåé 18 F-ÔÄà â îïóõîëè è â ðåôåðåíòíîì ó÷àñòêå. Ïðèìåíåíèå ýòîãî è äðóãèõ ïîëó-êîëè÷åñòâåííûõ ïîäõîäîâ ê ÏÝÒ äèàãíîñòèêå öåðåáðàëü-íûõ îïóõîëåé ïîäðîáíî ðàññìîòðåíî â ìîíîãðàôèè [3], à òàêaeå îáçîðå [29] è äðóãèõ ðàáîòàõ. Äîñòàòî÷íî ýôôåê-òèâíîé â îïðåäåëåíèè çëîêà÷åñòâåííîñòè îïóõîëè è/èëè ïðîãíîçà ÿâëÿåòñÿ ïðîñòàÿ è î÷åíü ýêîíîìè÷íàÿ ïî âðå-ìåíè âèçóàëüíàÿ îöåíêà, îñíîâàííàÿ íà âèçóàëüíîì îïðå-äåëåíèè ïàòîëîãè÷åñêîãî î÷àãà êàê ãèïîìåòàáîëè÷åñêîãî ("õîëîäíûé" î÷àã), ãèïåðìåòàáîëè÷åñêîãî ("ãîðÿ÷èé" î÷àã) èëè íåîòëè÷èìîãî îò îêðóaeàþùåé òêàíè.…”

From Homo sapiens to Homo in nexu (connected man): could functional imaging redefine the brain of a “new human species”?

“…A significant improvement in FDG PET could be achieved from a more rigorous and reliable methodological approach, including quantitative analysis [17] and a better understanding of glucose metabolic rate resulting from the activity of astrocytes/neuroglia, more than of neurons [18]. Further developments could be achieved from a deeper knowledge of mirror neurons, that fire both when an animal acts and when an animal observes the same action performed by another [19].…”