The quality of life in patients during intravesical treatment and correlation with local symptoms

Li, Wěi; Li, Qian; He, Lina; Li, Jianbo

doi:10.1179/1973947813y.0000000126

Cited by 25 publications

(28 citation statements)

References 13 publications

(12 reference statements)

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“…Previous publications on NMIBC included 4 crosssectional studies [5,11,13,14], 2 clinical trials evaluating intravesical BCG [17,18], and 3 observational prospective studies [12,15,16]. Of the latter 3, only 2 had pretreatment and posttreatment evaluations [12,16], and none of them used bladder cancer-specific HRQL instruments. These studies showed a relevant HRQL decline after bladder cancer diagnosis [12] and after intravesical treatment [16].…”

Section: Discussionmentioning

confidence: 99%

“…Of the latter 3, only 2 had pretreatment and posttreatment evaluations [12,16], and none of them used bladder cancer-specific HRQL instruments. These studies showed a relevant HRQL decline after bladder cancer diagnosis [12] and after intravesical treatment [16].…”

Section: Discussionmentioning

confidence: 99%

“…Currently, there are only a few published studies regarding HRQL in patients with nonmuscle-invasive bladder cancer (NMIBC) [5,[11][12][13][14][15][16][17][18] although patients are mostly diagnosed at this stage of the disease. Taking into account the current evidence gaps regarding HRQL of patients with bladder cancer and its high incidence rates in Spain, we aimed to describe the evolution over time of HRQL (measured by generic and bladder cancer-specific instruments) of Spanish patients with NMIBC and to examine the clinical and treatmentrelated factors associated with HRQL changes during the first year of disease management.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Quality of life in patients with non–muscle-invasive bladder cancer: One-year results of a multicentre prospective cohort study

Schmidt

Francés

Garín

et al. 2015

Urologic Oncology: Seminars and Original Investigations

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Quality of life in patients with non–muscle-invasive bladder cancer: One-year results of a multicentre prospective cohort study

Schmidt

Francés

Garín

et al. 2015

Urologic Oncology: Seminars and Original Investigations

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“…The core lower urinary tract symptom score (CLSS) questionnaire was recently developed by Dr Homma's group, and had been used as a reliable instrument for lower urinary tract symptoms (LUTS) assessment in several studies . However, the psychometric properties of the CLSS still need to be further evaluated.…”

mentioning

confidence: 99%

Editorial Comment to Core lower urinary tract symptom score questionnaire: A psychometric analysis

2014

Int J of Urology

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“…9,10 Currently there are only a few published studies regarding HRQOL in NMIBC population and the authors of the present study contemplate to evaluate this specific point in their next series. [11][12][13][14][15][16][17][18] (MIBC)…”

Section: Introductionmentioning

confidence: 99%

Single center experience of urinary bladder malignancy: a 10-year retrospective analysis of hospital data

et al. 2017

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INTRODUCTIONAlbeit the EAU, NCCN and AUA guidelines provide an excellent evidence-based protocol for the management of MIBC and NMIBC, these guidelines differ with respect to critical issues such as risk level definitions and management strategies. Implication of the aforementioned treatment policy in a vast subcontinent like ours has always been a challenge. The NE part of the country has always bore the brunt of heavy Oncological catastrophe like urinary bladder carcinoma related to extensive tobacco and pesticide usage. MIBC treatment usually encompasses radical cystectomy (RC) with adjuvant chemotherapy (AC)/ neo-adjuvant ABSTRACT Background: Albeit the EAU, NCCN and AUA guidelines provide an excellent evidence-based protocol for the management of MIBC and NMIBC, these guidelines differ with respect to critical issues such as risk level definitions and management strategies. The NE part of the country has always bore the brunt of heavy oncological catastrophe like urinary bladder carcinoma related to extensive tobacco and pesticide usage. MIBC treatment usually encompasses RC with AC/NAC (Level I evidence for NAC use in MIBC exist) but the majority of patients seen at our center have already progressed to advanced stage at presentation and could not undertake full treatment. Methods: Cancer registry of the last 10 yrs at Dept. of Urology and Renal Transplant Gauhati Medical College Hospital was searched for demographic, clinical, pathological and prognostic data and results summarized using statistical parameters of univariate analysis.Results: There were a total of 168 patients in the NMIBC group with a majority in the 60-70-year age group. The most common grade was G2 and all DM type 2 and CKD were significantly associated in all the patients analyzed.Chemical exposure in the form of pesticide and smoking was a constant phenomenon in all patients of NMIBC and MIBC (n=66) population. CKD was significantly associated in the MIBC population along with positive urine cytology. Conclusions: Despite a paucity of high level evidence regarding the majority of management topics in Urinary Bladder cancer in NE part of the country, there was general agreement among the various guideline panels and management guidelines at our institution. Identification of the upfront clinical parameters suggesting severity of disease and time to progression are the two most important domains which will decide the future of UB carcinoma treatment in this part of the world. Categories of evidence synthesized and grades of recommendations will have to be constantly gazed upon to modify and enhance treatment strategies.

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The quality of life in patients during intravesical treatment and correlation with local symptoms

Abstract: Long-term intravesical treatment could decline the QoL of patients. Local symptom was an important factor found to be associated with impairment of QoL. Appropriate therapy for local symptoms might improve the patients' overall QoL.

Cited by 25 publications

References 13 publications

Quality of life in patients with non–muscle-invasive bladder cancer: One-year results of a multicentre prospective cohort study

Quality of life in patients with non–muscle-invasive bladder cancer: One-year results of a multicentre prospective cohort study

Editorial Comment to Core lower urinary tract symptom score questionnaire: A psychometric analysis

Single center experience of urinary bladder malignancy: a 10-year retrospective analysis of hospital data

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