The pups’ endometrium morphology is affected by maternal malnutrition during suckling

Brasil, Flávia Bittencourt; Faria, T.; Costa, Waldemar S.; Sampaio, Francisco J.B.; Ramos, Cristiane F.

doi:10.1016/j.maturitas.2004.10.004

Cited by 12 publications

(16 citation statements)

References 39 publications

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“…Recently, we have shown that maternal protein and energy malnutrition during lactation leads to growth retardation and delay in the onset of puberty in female pups (Faria et al 2004). Also, protein and energy restriction during lactation leads to an atrophy of the uterine endometrial glands of the offspring at puberty (Brasil et al 2005).…”

Section: Introductionmentioning

confidence: 99%

Maternal malnutrition during lactation alters the folliculogenesis and gonadotropins and estrogen isoforms ovarian receptors in the offspring at puberty

Faria¹,

Brasil²,

Sampaio³

et al. 2008

Journal of Endocrinology

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In this study, we aimed to evaluate whether maternal malnutrition during lactation alters the folliculogenesis and the expression of the gonadotropins and estrogen isoforms ovarian receptors in the offspring at puberty. At parturition, dams were randomly assigned to the following groups: control (C) group, with free access to a standard laboratory diet containing 23% protein and protein-energy-restricted (PER) group, with free access to an isoenergy and protein-restricted diet containing 8% protein. After weaning, the female pups had free access to standard laboratory diet. The maternal malnutrition caused a significant increase in the number of

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Section: Introductionmentioning

confidence: 99%

Maternal malnutrition during lactation alters the folliculogenesis and gonadotropins and estrogen isoforms ovarian receptors in the offspring at puberty

Faria¹,

Brasil²,

Sampaio³

et al. 2008

Journal of Endocrinology

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“…On the other hand, exclusion criteria were as follows: (1) studies which evaluate the effect of folic acid consumption during gestation associated to any disease; (2) studies that evaluate maternal folic acid consumption during gestation and lactation or only during lactation and (3) articles that assess the folic acid consumption by their own offspring.…”

Section: Methodsmentioning

confidence: 99%

“…1 Suitable diet consumption during gestation is worthwhile for normal developing of offsprings and may determine their metabolic and hormonal status at adulthood. 2,3 It was stated that nutritional imbalance during critical periods, such as gestation, may predispose to diseases at adulthood.…”

Section: Introductionmentioning

confidence: 99%

Maternal folic acid consumption during gestation and its long-term effects on offspring's liver: a systematic review

Brasil

Amarante

Oliveira

2017

Rev. Bras. Saude Mater. Infant.

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“…Morphometric tools are also valuable in basic scientific research because they allow the evaluation of tissue remodeling in organs such as the heart and aorta (Silva-Junior et al, 2011), adipose tissue (Bringhenti et al, 2010), pancreas (Marques et al, 2010;Frantz et al, 2011), kidney (Cunha et al, 2008), and uterus (Brasil et al, 2005). In pathological diagnosis, the role for morphometry in kidney tumor evaluation has been criticized by some as unnecessary and impractical.…”

Section: Morphometrymentioning

confidence: 99%

Quantitative Morphology Update: Image Analysis

et al. 2013

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FERNANDES-SANTOS SUMMARY:Quantitative morphology is a reliable tool in developmental, clinical and aging biology. Quantitative data of histological improvement and/or impairment due to dietary manipulations or pharmacological interventions draws the attention of countless researchers worldwide. Morphometry allows a wide range of two-dimension analysis to be performed, whereas image segmentation allows the measurement of a single structure or the determination of the intensity of its color after adequate immunostaining or even the area occupied by a specific sort of cell. When it comes to unbiased analysis, consideration should be given to suitable tissue perfusion, fixation and embedding, avoiding artifacts. Furthermore, tissue shrinkage should be taken into account. In order to ensure reproducibility, one of the most important principles in scientific research, and to allow different groups to be compared, image acquisition and image segmentation emerge as crucial steps and should be standardized. This paper aims to approach some important care for appropriate tissue processing and evaluation, and shows some practical examples of how morphometry and image segmentation can be applied to your experiment.

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The pups’ endometrium morphology is affected by maternal malnutrition during suckling

Cited by 12 publications

References 39 publications

Maternal malnutrition during lactation alters the folliculogenesis and gonadotropins and estrogen isoforms ovarian receptors in the offspring at puberty

Maternal malnutrition during lactation alters the folliculogenesis and gonadotropins and estrogen isoforms ovarian receptors in the offspring at puberty

Maternal folic acid consumption during gestation and its long-term effects on offspring's liver: a systematic review

Quantitative Morphology Update: Image Analysis

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