The Public Health Impact of Pediatric Caustic Ingestion Injuries

Johnson, Christopher M.; Brigger, Matthew T.

doi:10.1001/jamaoto.2013.672

Cited by 44 publications

(49 citation statements)

References 12 publications

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“…Patients initially seek home-based therapy by traditional healers7 and only present at the hospital after complications had set in. Furthermore, some patients also default at the follow up clinic [11–13]. …”

Section: Introductionmentioning

confidence: 99%

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Corrosive oesophageal injuries: a preventable menace

Adedeji¹,

Tobih²,

Olaosun³

et al. 2013

Pan Afr Med J

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IntroductionPotentially catastrophic presentations and lifelong complications resulting from corrosive ingestions in humans is one of the most challenging situations encountered in clinical medical practice. This study reviewed pattern, mechanisms and associated socio-medical challenges with ingestion of corrosive agents as seen in a tertiary health institution in South-western Nigeria.MethodsA retrospective review of all patients that were managed for corrosive ingestion at Ladoke Akintola University of Technology Teaching Hospital, Osogbo, Osun State, Nigeria, over a seven year period.ResultsA total of 28 patients M:F: 1.6:1. There were 7 children and 21 adults. Majority (78.6%) of the patients ingested alkaline substances. Accidental ingestion occurred in 28.6% while 71.4% resulted from deliberate self harm especially among adults (66.7%). Almost two thirds (64.3%) of the patients presented after 48hrs of ingestion. Patients who presented early were managed conservatively. Most patients (64.3%) who presented late had nutritional and fluid rehabilitation. Two patients died from oesophageal perforation and resulting septicaemia. Psychiatric evaluation revealed that seven adults (25%) had psychotic illness while (42.9%) of the patients developed oesophageal strictures. Short segment strictures were managed with oesophageal dilatation with good outcome while long and multiple segment strictures were referred to cardiothoracic surgeons for management.ConclusionCorrosive oesophageal injuries remain a prevalent and preventable condition in the developing countries. Preventive strategies should include regulation and packaging of corrosive substances, organization of psychiatric services, and education of the population on corrosive ingestion.

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Section: Introductionmentioning

confidence: 99%

“…In the western world, the incidence of corrosive esophageal injuries has declined due to legislative effort and stricter packaging standards [3, 13]. Unfortunately this may not be the situation in the developing countries [6].…”

Section: Introductionmentioning

confidence: 99%

Corrosive oesophageal injuries: a preventable menace

Adedeji¹,

Tobih²,

Olaosun³

et al. 2013

Pan Afr Med J

View full text Add to dashboard Cite

show abstract

“…continues to impose a significant burden on psychological illness, family and health social care [24].…”

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 99%

Pirfenidone prevents rat esophageal stricture formation

Orozco-Pérez

Aguirre-Jáuregui

Salazar-Montes

et al. 2015

Journal of Surgical Research

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“…1 Over 200,000 of such cases were reported in the United States in 2009 alone, 2 of which 807 required hospitalization. 3 Accurate figures on the incidence of this type of injury in developing countries are not available however the large number of children requiring esophageal replacement for caustic injury indicates that this is a serious public health problem. 4 The extent of the esophageal injury after ingestion of caustic substances has been determined using different methods, such as traditional radiology, CT-scan, ultrasound and endoscopy.…”

Section: Introductionmentioning

confidence: 99%